Journal
PATHOGENS
Volume 9, Issue 7, Pages -Publisher
MDPI
DOI: 10.3390/pathogens9070528
Keywords
Listeria monocytogenes; virulence; biofilm; antimicrobial resistance; environmental stress
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Funding
- South African Medical Research Council [SAMRC/UFH/P790]
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Listeria monocytogenesis a ubiquitous opportunistic pathogen responsible for the well-known listeriosis disease. This bacterium has become a common contaminant of food, threatening the food processing industry. Once consumed, the pathogen is capable of traversing epithelial barriers, cellular invasion, and intracellular replication through the modulation of virulence factors such as internalins and haemolysins. Mobile genetic elements (plasmids and transposons) and other sophisticated mechanisms are thought to contribute to the increasing antimicrobial resistance ofL. monocytogenes. The environmental persistence of the pathogen is aided by its ability to withstand environmental stresses such as acidity, cold stress, osmotic stress, and oxidative stress. This review seeks to give an insight intoL. monocytogenesbiology, with emphasis on its virulence factors, antimicrobial resistance, and adaptations to environmental stresses.
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