Related references
Note: Only part of the references are listed.Differential Effects of Rapamycin and Metformin in Combination With Rapamycin on Mechanisms of Proteostasis in Cultured Skeletal Myotubes
Christopher A. Wolff et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2020)
Brain Protein Synthesis Rates in the UM-HET3 Mouse Following Treatment With Rapamycin or Rapamycin With Metformin
Justin J. Reid et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2020)
Short-term Calorie Restriction and 17α-Estradiol Administration Elicit Divergent Effects on Proteostatic Processes and Protein Content in Metabolically Active Tissues
Benjamin F. Miller et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2020)
Metformin inhibits mitochondrial adaptations to aerobic exercise training in older adults
Adam R. Konopka et al.
AGING CELL (2019)
Inter-organ cross-talk in metabolic syndrome
Christina Priest et al.
NATURE METABOLISM (2019)
Targeting mitochondrial function and proteostasis to mitigate dynapenia
Robert V. Musci et al.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY (2018)
Metformin reduces glucose intolerance caused by rapamycin treatment in genetically heterogeneous female mice
Roxanne Weiss et al.
AGING-US (2018)
Differential effects of vitamin C or protandim on skeletal muscle adaptation to exercise
Danielle R. Bruns et al.
JOURNAL OF APPLIED PHYSIOLOGY (2018)
Metformin Is a Direct SIRT1-Activating Compound: Computational Modeling and Experimental Validation
Elisabet Cuyas et al.
FRONTIERS IN ENDOCRINOLOGY (2018)
Mechanisms of In Vivo Ribosome Maintenance Change in Response to Nutrient Signals
Andrew D. Mathis et al.
MOLECULAR & CELLULAR PROTEOMICS (2017)
Mitochondrial proteostasis as a shared characteristic of slowed aging: the importance of considering cell proliferation
Karyn L. Hamilton et al.
JOURNAL OF PHYSIOLOGY-LONDON (2017)
Regulation of hepatic glucose metabolism in health and disease
Max C. Petersen et al.
NATURE REVIEWS ENDOCRINOLOGY (2017)
NIA Interventions Testing Program: Investigating Putative Aging Intervention Agents in a Genetically Heterogeneous Mouse Model
Nancy L. Nadon et al.
EBIOMEDICINE (2017)
Sirtuins at the crossroads of stemness, aging, and cancer
Carol O'Callaghan et al.
AGING CELL (2017)
DeuteRater: a tool for quantifying peptide isotope precision and kinetic proteomics
Bradley C. Naylor et al.
BIOINFORMATICS (2017)
Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an -glucosidase inhibitor or a Nrf2-inducer
Randy Strong et al.
AGING CELL (2016)
Rapamycin transiently induces mitochondrial remodeling to reprogram energy metabolism in old hearts
Ying Ann Chiao et al.
AGING-US (2016)
Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice
Alessandro Bitto et al.
ELIFE (2016)
Subacute calorie restriction and rapamycin discordantly alter mouse liver proteome homeostasis and reverse aging effects
Pabalu P. Karunadharma et al.
AGING CELL (2015)
Long-lived Snell dwarf mice display increased proteostatic mechanisms that are not dependent on decreased mTORC1 activity
Joshua C. Drake et al.
AGING CELL (2015)
The Biology of Proteostasis in Aging and Disease
Johnathan Labbadia et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 84 (2015)
Current controlled vocabularies are insufficient to uniquely map molecular entities to mass spectrometry signal
Rob Smith et al.
BMC BIOINFORMATICS (2015)
Modeling the contribution of individual proteins to mixed skeletal muscle protein synthetic rates over increasing periods of label incorporation
Benjamin F. Miller et al.
JOURNAL OF APPLIED PHYSIOLOGY (2015)
The measurement of protein synthesis for assessing proteostasis in studies of slowed aging
Benjamin F. Miller et al.
AGEING RESEARCH REVIEWS (2014)
Altered proteome turnover and remodeling by short-term caloric restriction or rapamycin rejuvenate the aging heart
Dao-Fu Dai et al.
AGING CELL (2014)
Rapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction
Richard A. Miller et al.
AGING CELL (2014)
Long-lived crowded-litter mice have an age-dependent increase in protein synthesis to DNA synthesis ratio and mTORC1 substrate phosphorylation
Joshua C. Drake et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2014)
Geroscience: Linking Aging to Chronic Disease
Brian K. Kennedy et al.
CELL (2014)
The role of protein clearance mechanisms in organismal ageing and age-related diseases
David Vilchez et al.
NATURE COMMUNICATIONS (2014)
Metformin directly acts on mitochondria to alter cellular bioenergetics
Sylvia Andrzejewski et al.
CANCER & METABOLISM (2014)
Rapamycin doses sufficient to extend lifespan do not compromise muscle mitochondrial content or endurance
Lan Ye et al.
AGING-US (2013)
Cross-talk between skeletal muscle and immune cells: muscle-derived mediators and metabolic implications
Nicolas J. Pillon et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2013)
The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling
Laurent Mouchiroud et al.
CELL (2013)
Duration of Rapamycin Treatment Has Differential Effects on Metabolism in Mice
Yimin Fang et al.
CELL METABOLISM (2013)
Assessment of Mitochondrial Biogenesis and mTORC1 Signaling During Chronic Rapamycin Feeding in Male and Female Mice
Joshua C. Drake et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2013)
Nutrient Signaling in Protein Homeostasis: An Increase in Quantity at the Expense of Quality
Crystal S. Conn et al.
SCIENCE SIGNALING (2013)
Less is more: improving proteostasis by translation slow down
Michael Y. Sherman et al.
TRENDS IN BIOCHEMICAL SCIENCES (2013)
Metformin improves healthspan and lifespan in mice
Alejandro Martin-Montalvo et al.
NATURE COMMUNICATIONS (2013)
Lifelong rapamycin administration ameliorates age-dependent cognitive deficits by reducing IL-1ß and enhancing NMDA signaling
Smita Majumder et al.
AGING CELL (2012)
Stable isotope-labelling analysis of the impact of inhibition of the mammalian target of rapamycin on protein synthesis
Yilin Huo et al.
BIOCHEMICAL JOURNAL (2012)
Chronic mTOR inhibition by rapamycin induces muscle insulin resistance despite weight loss in rats
N. Deblon et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
PEAKS DB: De Novo Sequencing Assisted Database Search for Sensitive and Accurate Peptide Identification
Jing Zhang et al.
MOLECULAR & CELLULAR PROTEOMICS (2012)
The Effect of Long Term Calorie Restriction on in Vivo Hepatic Proteostatis: A Novel Combination of Dynamic and Quantitative Proteomics
John C. Price et al.
MOLECULAR & CELLULAR PROTEOMICS (2012)
Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity
Dudley W. Lamming et al.
SCIENCE (2012)
Rapamycin Reverses Elevated mTORC1 Signaling in Lamin A/C-Deficient Mice, Rescues Cardiac and Skeletal Muscle Function, and Extends Survival
Fresnida J. Ramos et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
All-Cause, Liver-Related, and Non-Liver-Related Mortality Among HCV-Infected Individuals in the General US Population
Samer S. El-Kamary et al.
CLINICAL INFECTIOUS DISEASES (2011)
Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice
Richard A. Miller et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2011)
A Liver-Derived Secretory Protein, Selenoprotein P, Causes Insulin Resistance
Hirofumi Misu et al.
CELL METABOLISM (2010)
4E-BP Extends Lifespan upon Dietary Restriction by Enhancing Mitochondrial Activity in Drosophila
Brian M. Zid et al.
CELL (2009)
Skeletal Muscle Insulin Resistance Is the Primary Defect in Type 2 Diabetes
Ralph A. DeFronzo et al.
DIABETES CARE (2009)
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
David E. Harrison et al.
NATURE (2009)
Universal sample preparation method for proteome analysis
Jacek R. Wisniewski et al.
NATURE METHODS (2009)
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
Da Wei Huang et al.
NATURE PROTOCOLS (2009)
Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans
Kally Z. Pan et al.
AGING CELL (2007)
Efficient calculation of accurate masses of isotopic peaks
AL Rockwood et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2006)
The underappreciated role of muscle in health and disease
Robert R. Wolfe
AMERICAN JOURNAL OF CLINICAL NUTRITION (2006)
Strength, but not muscle mass, is associated with mortality in the health, aging and body composition study cohort
AB Newman et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2006)
Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability
I Janssen et al.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2002)