Related references
Note: Only part of the references are listed.Inhibiting WNT and NOTCH in renal cancer stem cells and the implications for human patients
Annika Fendler et al.
NATURE COMMUNICATIONS (2020)
Signal transducer and activator of transcription (STAT)-5: an opportunity for drug development in oncohematology
Carlota Recio et al.
ONCOGENE (2019)
Resistance to neoadjuvant chemotherapy in triple-negative breast cancer mediated by a reversible drug-tolerant state
Gloria V. Echeverria et al.
SCIENCE TRANSLATIONAL MEDICINE (2019)
Andrographolide antagonizes the cigarette smoke-induced epithelial-mesenchymal transition and pulmonary dysfunction through anti-inflammatory inhibiting HOTAIR
Haibo Xia et al.
TOXICOLOGY (2019)
Reverse signaling by semaphorin 4C elicits SMAD1/5-and ID1/3-dependent invasive reprogramming in cancer cells
Sreeharsha Gurrapu et al.
SCIENCE SIGNALING (2019)
Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling
Rachel Eyre et al.
NATURE COMMUNICATIONS (2019)
Andrographolide enhances redox status of liver cells by regulating microRNA expression
Swati Khole et al.
FREE RADICAL BIOLOGY AND MEDICINE (2019)
Andrographolide binds to ATP-binding pocket of VEGFR2 to impede VEGFA-mediated tumor-angiogenesis
Kirti Kajal et al.
SCIENTIFIC REPORTS (2019)
Andrographolide Enhances TRAIL-Induced Apoptosis via p53-Mediated Death Receptors Up-Regulation and Suppression of the NF-kappa B Pathway in Bladder Cancer Cells
Yuyou Deng et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2019)
Andrographolide sensitizes prostate cancer cells to TRAIL-induced apoptosis
Ruo-Jing Wei et al.
ASIAN JOURNAL OF ANDROLOGY (2018)
A silyl andrographolide analogue suppresses Wnt/beta-catenin signaling pathway in colon cancer
Somrudee Reabroi et al.
BIOMEDICINE & PHARMACOTHERAPY (2018)
PSPC1 mediates TGF-β1 autocrine signalling and Smad2/3 target switching to promote EMT, stemness and metastasis
Hsi-Wen Yeh et al.
NATURE CELL BIOLOGY (2018)
Targeting the NLRP3 inflammasome in inflammatory diseases
Matthew S. J. Mangan et al.
NATURE REVIEWS DRUG DISCOVERY (2018)
Patient-derived organoids model treatment response of metastatic gastrointestinal cancers
Georgios Vlachogiannis et al.
SCIENCE (2018)
MicroRNAs in the prognosis and therapy of colorectal cancer: From bench to bedside
Kenneth K. W. To et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2018)
Frizzled-8 integrates Wnt-11 and transforming growth factor-β signaling in prostate cancer
Virginia Murillo-Garzon et al.
NATURE COMMUNICATIONS (2018)
The anti-cancer activity of an andrographolide analogue functions through a GSK-3β-independent Wnt/β-catenin signaling pathway in colorectal cancer cells
Somrudee Reabroi et al.
SCIENTIFIC REPORTS (2018)
mTOR signalling and cellular metabolism are mutual determinants in cancer
Dirk Mossmann et al.
NATURE REVIEWS CANCER (2018)
MicroRNA-targeted therapeutics for lung cancer treatment
Jing Xue et al.
EXPERT OPINION ON DRUG DISCOVERY (2017)
Andrographolide impedes cancer stemness and enhances radio-sensitivity in oral carcinomas via miR-218 activation
Po-Yu Yang et al.
ONCOTARGET (2017)
Andrographolide Inhibits Angiogenesis by Inhibiting the Mir-21-5p/TIMP3 Signaling Pathway
Jianwei Dai et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2017)
Andrographolide Induces Cell Cycle Arrest and Apoptosis of Chondrosarcoma by Targeting TCF-1/SOX9 Axis
Huan-Tian Zhang et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2017)
Diterpenes and Their Derivatives as Potential Anticancer Agents
Muhammad Torequl Islam
PHYTOTHERAPY RESEARCH (2017)
In vivo inhibitory activity of andrographolide derivative ADN-9 against liver cancer and its mechanisms involved in inhibition of tumor angiogenesis
Wei Yang et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2017)
Andrographolide suppresses proliferation of human colon cancer SW620 cells through the TLR4/NF-κB/MMP-9 signaling pathway
Rui Zhang et al.
ONCOLOGY LETTERS (2017)
Increased reactive oxygen species levels cause ER stress and cytotoxicity in andrographolide treated colon cancer cells
Aditi Banerjee et al.
ONCOTARGET (2017)
Andrographolide Induces Autophagic Cell Death and Inhibits Invasion and Metastasis of Human Osteosarcoma Cells in An Autophagy-Dependent Manner
Ying Liu et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2017)
Exploring the TRAILs less travelled: TRAIL in cancer biology and therapy
Silvia von Karstedt et al.
NATURE REVIEWS CANCER (2017)
Andrographolide inhibits multiple myeloma cells by inhibiting the TLR4/NF-κB signaling pathway
Hui Gao et al.
MOLECULAR MEDICINE REPORTS (2016)
SMARCA4/Brg1 coordinates genetic and epigenetic networks underlying Shh-type medulloblastoma development
X. Shi et al.
ONCOGENE (2016)
Plant metabolism, the diverse chemistry set of the future
Eleanore T. Wurtzel et al.
SCIENCE (2016)
Inhibition of autophagy by andrographolide resensitizes cisplatin-resistant non-small cell lung carcinoma cells via activation of the Akt/mTOR pathway
Shanwei Mi et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2016)
The role of JAK/STAT signalling in the pathogenesis, prognosis and treatment of solid tumours
S. J. Thomas et al.
BRITISH JOURNAL OF CANCER (2015)
Inflammasomes: mechanism of action, role in disease, and therapeutics
Haitao Guo et al.
NATURE MEDICINE (2015)
Andrographolide Analogue Induces Apoptosis and Autophagy Mediated Cell Death in U937 Cells by Inhibition of PI3K/Akt/mTOR Pathway
Deepak Kumar et al.
PLOS ONE (2015)
A ndrographolide inhibits hypoxia-inducible factor-1 through phosphatidylinositol 3-kinase/AKT pathway and suppresses breast cancer growth
Jie Li et al.
ONCOTARGETS AND THERAPY (2015)
Small molecule-driven mitophagy-mediated NLRP3 inflammasome inhibition is responsible for the prevention of colitis-associated cancer
Wenjie Guo et al.
AUTOPHAGY (2014)
Andrographolide prevents human breast cancer-induced osteoclastic bone loss via attenuated RANKL signaling
Zanjing Zhai et al.
BREAST CANCER RESEARCH AND TREATMENT (2014)
Andrographolide inhibits tumor angiogenesis via blocking VEGFA/VEGFR2-MAPKs signaling cascade
Kaikai Shen et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2014)
Andrographolide inhibits melanoma tumor growth by inactivating the TLR4/NF-κB signaling pathway
Qian-Qian Zhang et al.
MELANOMA RESEARCH (2014)
Antitumor Activity of Monoterpenes Found in Essential Oils
Marianna Vieira Sobral et al.
TheScientificWorldJOURNAL (2014)
A Review on Anti-Inflammatory Activity of Monoterpenes
Rita de Cassia da Silveira e Sa et al.
MOLECULES (2013)
Therapeutic modulators of STAT signalling for human diseases
Gabriella Miklossy et al.
NATURE REVIEWS DRUG DISCOVERY (2013)
On the TRAIL to successful cancer therapy? Predicting and counteracting resistance against TRAIL-based therapeutics
L. Y. Dimberg et al.
ONCOGENE (2013)
Andrographolide causes apoptosis via inactivation of STAT3 and Akt and potentiates antitumor activity of gemcitabine in pancreatic cancer
Guo-Qing Bao et al.
TOXICOLOGY LETTERS (2013)
A novel semi-synthetic andrographolide analogue A5 inhibits tumor angiogenesis via blocking the VEGFR2-p38/ ERK1/2 signal pathway
Chenyuan Gong et al.
BIOSCIENCE TRENDS (2013)
WNT signalling pathways as therapeutic targets in cancer
Jamie N. Anastas et al.
NATURE REVIEWS CANCER (2013)
The complex world of WNT receptor signalling
Christof Niehrs
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
Mining the Biodiversity of Plants: A Revolution in the Making
Vincenzo De Luca et al.
SCIENCE (2012)
Randomized Phase II Study of Dulanermin in Combination With Paclitaxel, Carboplatin, and Bevacizumab in Advanced Non-Small-Cell Lung Cancer
Jean-Charles Soria et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
Genome-Wide RNAi Screen Reveals Disease-Associated Genes That Are Common to Hedgehog and Wnt Signaling
Leni S. Jacob et al.
SCIENCE SIGNALING (2011)
Inhibition of the JAK-STAT3 pathway by andrographolide enhances chemosensitivity of cancer cells to doxorubicin
Jing Zhou et al.
BIOCHEMICAL PHARMACOLOGY (2010)
Development of Immunohistochemistry Assays to Assess GALNT14 and FUT3/6 in Clinical Trials of Dulanermin and Drozitumab
Howard M. Stern et al.
CLINICAL CANCER RESEARCH (2010)
mToR signaling and drug development in cancer
Janet Dancey
NATURE REVIEWS CLINICAL ONCOLOGY (2010)
Sonic hedgehog paracrine signaling regulates metastasis and lymphangiogenesis in pancreatic cancer
J. M. Bailey et al.
ONCOGENE (2009)
Andrographolide sensitizes cancer cells to TRAIL-induced apoptosis via p53-mediated death receptor 4 up-regulation
Jing Zhou et al.
MOLECULAR CANCER THERAPEUTICS (2008)
Sonic Hedgehog promotes multiple drug resistance by regulation of drug transport
J. Sims-Mourtada et al.
ONCOGENE (2007)
The function of terpene natural products in the natural world
Jonathan Gershenzon et al.
NATURE CHEMICAL BIOLOGY (2007)
Regulation of matrix metalloproteinase gene expression
Chunhong Yan et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2007)
Mining the Wnt pathway for cancer therapeutics
Nick Barker et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Andropanolide and isoandrographolide, minor diterpenoids from Andrographis paniculata:: Structure and X-ray crystallographic analysis
S Pramanick et al.
JOURNAL OF NATURAL PRODUCTS (2006)
Phase I clinical and pharmacokinetic study of PTK/ZK, a multiple VEGF receptor inhibitor, in patients with liver metastases from solid tumours
K Mross et al.
EUROPEAN JOURNAL OF CANCER (2005)
Mechanisms of Disease: insights into the emerging role of signal transducers and activators of transcription in cancer
EB Haura et al.
NATURE CLINICAL PRACTICE ONCOLOGY (2005)
Angiogenesis inhibitors in clinical development; where are we now and where are we going?
FALM Eskens
BRITISH JOURNAL OF CANCER (2004)
Determination and variation of three active diterpenoids in Andrographis paniculata (Burm.f.) Nees
N Pholphana et al.
PHYTOCHEMICAL ANALYSIS (2004)