Related references
Note: Only part of the references are listed.Allostery in Its Many Disguises: From Theory to Applications
Shoshana J. Wodak et al.
STRUCTURE (2019)
Two PKA RIα holoenzyme states define ATP as an isoform-specific orthosteric inhibitor that competes with the allosteric activator, cAMP
Tsan-Wen Lu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Positive Cooperativity in Substrate Binding by Human Thymidylate Synthase
Jeffrey P. Bonin et al.
BIOPHYSICAL JOURNAL (2019)
A Conserved Allosteric Pathway in Tyrosine Kinase Regulation
William M. Marsiglia et al.
STRUCTURE (2019)
Cushing's syndrome driver mutation disrupts protein kinase A allosteric network, altering both regulation and substrate specificity
Caitlin Walker et al.
SCIENCE ADVANCES (2019)
Activation of PKA via asymmetric allosteric coupling of structurally conserved cyclic nucleotide binding domains
Yuxin Hao et al.
NATURE COMMUNICATIONS (2019)
Cooperative subunit dynamics modulate p97 function
Rui Huang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
The oligomerization state of bacterial enzyme I (EI) determines EI's allosteric stimulation or competitive inhibition by α-ketoglutarate
Trang T. Nguyen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Role of Dimers in the cAMP-Dependent Activation of Hyperpolarization-Activated Cyclic-Nucleotide-Modulated (HCN) Ion Channels
Bryan VanSchouwen et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2018)
Mechanism of Selective Enzyme Inhibition through Uncompetitive Regulation of an Allosteric Agonist
Stephen Boulton et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)
Conservation of Dynamics Associated with Biological Function in an Enzyme Superfamily
Chitra Narayanan et al.
STRUCTURE (2018)
cAMP: From Long-Range Second Messenger to Nanodomain Signalling
Nshunge Musheshe et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2018)
Prkar1a gene knockout in the pancreas leads to neuroendocrine tumorigenesis
Emmanouil Saloustros et al.
ENDOCRINE-RELATED CANCER (2017)
Atomic view of the energy landscape in the allosteric regulation of Abl kinase
Tamjeed Saleh- et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
Atomic view of the energy landscape in the allosteric regulation of Abl kinase
Tamjeed Saleh- et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
Pseudoscaffolds and anchoring proteins: the difference is in the details
Stacey Aggarwal-Howarth et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2017)
Divalent Metal Ions Mg2+ and Ca2+ Have Distinct Effects on Protein Kinase A Activity and Regulation
Matthias J. Knape et al.
ACS CHEMICAL BIOLOGY (2015)
Measurement of State-Specific Association Constants in Allosteric Sensors through Molecular Stapling and NMR
Kody J. Moleschi et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)
Mapping the Free Energy Landscape of PKA Inhibition and Activation: A Double-Conformational Selection Model for the Tandem cAMP-Binding Domains of PKA RIα
Madoka Akimoto et al.
PLOS BIOLOGY (2015)
The ensemble nature of allostery
Hesam N. Motlagh et al.
NATURE (2014)
Allosteric targeting of receptor tyrosine kinases
Frederik De Smet et al.
NATURE BIOTECHNOLOGY (2014)
Signaling through dynamic linkers as revealed by PKA
Madoka Akimoto et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Conformational Motions Regulate Phosphoryl Transfer in Related Protein Tyrosine Phosphatases
Sean K. Whittier et al.
SCIENCE (2013)
Structural and Energetic Basis of Allostery
Vincent J. Hilser et al.
ANNUAL REVIEW OF BIOPHYSICS, VOL 41 (2012)
Assembly of allosteric macromolecular switches: lessons from PKA
Susan S. Taylor et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
Agonism/antagonism switching in allosteric ensembles
Hesam N. Motlagh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Mapping allostery through the covariance analysis of NMR chemical shifts
Rajeevan Selvaratnam et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Communication between Tandem cAMP Binding Domains in the Regulatory Subunit of Protein Kinase A-Iα as Revealed by Domain-silencing Mutations
E. Tyler McNicholl et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Cyclic AMP- and (Rp)-cAMPS-induced Conformational Changes in a Complex of the Catalytic and Regulatory (RIα) Subunits of Cyclic AMP-dependent Protein Kinase
Ganesh S. Anand et al.
MOLECULAR & CELLULAR PROTEOMICS (2010)
Cyclic AMP Analog Blocks Kinase Activation by Stabilizing Inactive Conformation: Conformational Selection Highlights a New Concept in Allosteric Inhibitor Design
Suguna Badireddy et al.
MOLECULAR & CELLULAR PROTEOMICS (2010)
Toward an Accurate Determination of Free Energy Landscapes in Solution States of Proteins
Alfonso De Simone et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
Cyclic nucleotide analogs as probes of signaling pathways
Heiko Poppe et al.
NATURE METHODS (2008)
PKA-I holoenzyme structure reveals a mechanism for cAMP-dependent activation
Choel Kim et al.
CELL (2007)
Carney complex: the first 20 years
Sosipatros A. Boikos et al.
CURRENT OPINION IN ONCOLOGY (2007)
Translational regulatory mechanisms generate N-terminal glucocorticoid receptor isoforms with unique transcriptional target genes
NZ Lu et al.
MOLECULAR CELL (2005)
Comparative PRKAR1A genotype-phenotype analyses in humans with Carney complex and prkar1a haploinsufficient mice
M Veugelers et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Crystal structures of RIα subunit of cyclic adenosine 5'-monophosphate (cAMP)-dependent protein kinase complexed with (Rp)-adenosine 3',5'-cyclic monophosphothioate and (Sp)-adenosine 3',5'-cyclic monophosphothioate, the phosphothioate analogues of cAMP
J Wu et al.
BIOCHEMISTRY (2004)
Rlα subunit of PKA:: A cAMP-free structure reveals a hydrophobic capping mechanism for docking cAMP into site B
J Wu et al.
STRUCTURE (2004)
Protein kinases - the major drug targets of the twenty-first century?
P Cohen
NATURE REVIEWS DRUG DISCOVERY (2002)
Share Paper
