Related references
Note: Only part of the references are listed.Purification of mRNA Encoding Chimeric Antigen Receptor Is Critical for Generation of a Robust T-Cell Response
Jessica B. Foster et al.
HUMAN GENE THERAPY (2019)
Double-Stranded RNA Sensors and Modulators in Innate Immunity
Sun Hur
Annual Review of Immunology (2019)
Messenger RNA therapy for rare genetic metabolic diseases
Pedro Berraondo et al.
GUT (2019)
The Emerging Role of In Vitro-Transcribed mRNA in Adoptive T Cell Immunotherapy
Jessica B. Foster et al.
MOLECULAR THERAPY (2019)
Durable anticancer immunity from intratumoral administration of IL-23, IL-36γ, and OX40L mRNAs
Susannah L. Hewitt et al.
SCIENCE TRANSLATIONAL MEDICINE (2019)
Intradermal delivery of modified mRNA encoding VEGF-A in patients with type 2 diabetes
Li-Ming Gan et al.
NATURE COMMUNICATIONS (2019)
mRNA vaccines against H10N8 and H7N9 influenza viruses of pandemic potential are immunogenic and well tolerated in healthy adults in phase 1 randomized clinical trials
Robert A Feldman et al.
VACCINE (2019)
Optimizing Modified mRNA In Vitro Synthesis Protocol for Heart Gene Therapy
Yoav Hadas et al.
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2019)
Advances in mRNA Vaccines for Infectious Diseases
Cuiling Zhang et al.
FRONTIERS IN IMMUNOLOGY (2019)
mRNA vaccines - a new era in vaccinology
Norbert Pardi et al.
NATURE REVIEWS DRUG DISCOVERY (2018)
An origin of the immunogenicity of in vitro transcribed RNA
Xin Mu et al.
NUCLEIC ACIDS RESEARCH (2018)
A minimal RNA ligand for potent RIG-I activation in living mice
Melissa M. Linehan et al.
SCIENCE ADVANCES (2018)
Preclinical and Clinical Demonstration of Immunogenicity by mRNA Vaccines against H10N8 and H7N9 Influenza Viruses
Kapil Bahl et al.
MOLECULAR THERAPY (2017)
Boosting Intracellular Delivery of Lipid Nanoparticle-Encapsulated mRNA
Siddharth Patel et al.
NANO LETTERS (2017)
Recognition of Endogenous Nucleic Acids by the Innate Immune System
Axel Roers et al.
IMMUNITY (2016)
RIG-I-Mediated STING Upregulation Restricts Herpes Simplex Virus 1 Infection
Yiliu Liu et al.
JOURNAL OF VIROLOGY (2016)
RNAs Containing Modified Nucleotides Fail To Trigger RIG-I Conformational Changes for Innate Immune Signaling
Ann Fiegen Durbin et al.
MBIO (2016)
Transfected Poly(I:C) Activates Different dsRNA Receptors, Leading to Apoptosis or Immunoadjuvant Response in Androgen-independent Prostate Cancer Cells
Sara Palchetti et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Stimulation of the RIG-I/MAVS Pathway by Polyinosinic: Polycytidylic Acid Upregulates IFN-β in Airway Epithelial Cells with Minimal Costimulation of IL-8
Nurlan Dauletbaev et al.
JOURNAL OF IMMUNOLOGY (2015)
Sequence-engineered mRNA Without Chemical Nucleoside Modifications Enables an Effective Protein Therapy in Large Animals
Andreas Thess et al.
MOLECULAR THERAPY (2015)
Toll-like receptor 8 senses degradation products of single-stranded RNA
Hiromi Tanji et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
Toll-like receptor 8 senses degradation products of single-stranded RNA
Hiromi Tanji et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
Recombinant messenger RNA technology and its application in cancer immunotherapy, transcript replacement therapies, pluripotent stem cell induction, and beyond
Britta Vallazza et al.
WILEY INTERDISCIPLINARY REVIEWS-RNA (2015)
TLR Cross-talk Confers Specificity to Innate Immunity
Rebecca S. T. Tan et al.
INTERNATIONAL REVIEWS OF IMMUNOLOGY (2014)
RIG-I Forms Signaling-Competent Filaments in an ATP-Dependent, Ubiquitin-Independent Manner
Alys Peisley et al.
MOLECULAR CELL (2013)
IRF-3, IRF-5, and IRF-7 Coordinately Regulate the Type I IFN Response in Myeloid Dendritic Cells Downstream of MAVS Signaling
Helen M. Lazear et al.
PLOS PATHOGENS (2013)
CXCL10/IP-10 in infectious diseases pathogenesis and potential therapeutic implications
Mingli Liu et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2011)
Expression of therapeutic proteins after delivery of chemically modified mRNA in mice
Michael S. D. Kormann et al.
NATURE BIOTECHNOLOGY (2011)
Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA
Katalin Kariko et al.
NUCLEIC ACIDS RESEARCH (2011)
Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation
Bart R. Anderson et al.
NUCLEIC ACIDS RESEARCH (2010)
Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets
Nahum Sonenberg et al.
CELL (2009)
Activation of interferon regulatory factor-3 via toll-like receptor 3 and immunomodulatory functions detected in A549 lung epithelial cells exposed to misplaced U1-snRNA
Christian D. Sadik et al.
NUCLEIC ACIDS RESEARCH (2009)
Functions of the cytoplasmic RNA sensors RIG-I and MDA-5: Key regulators of innate immunity
Paola M. Barral et al.
PHARMACOLOGY & THERAPEUTICS (2009)
Essential role of the N-terminal domain in the regulation of RIG-I ATPase activity
Peter Gee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Incorporation of Pseudouridine Into mRNA Yields Superior Nonimmunogenic Vector With Increased Translational Capacity and Biological Stability
Katalin Kariko et al.
MOLECULAR THERAPY (2008)
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
Hiroki Ishikawa et al.
NATURE (2008)
Collaboration between the innate immune receptors dectin-1, TLRs, and Nods
David M. Underhill
IMMUNOLOGICAL REVIEWS (2007)
Innate immune recognition of viral infection
T Kawai et al.
NATURE IMMUNOLOGY (2006)
IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction
T Kawai et al.
NATURE IMMUNOLOGY (2005)
Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
SS Diebold et al.
SCIENCE (2004)
Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8
F Heil et al.
SCIENCE (2004)