Journal
CHEMISTRYSELECT
Volume 5, Issue 21, Pages 6424-6429Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/slct.202001012
Keywords
Alkylation; Amide; Cinchona Alkaloids; Enantioselectivity; Phase-transfer catalysis
Categories
Funding
- Poland's National Science Centre [2016/21/B/ST5/03352]
Ask authors/readers for more resources
We investigated the synthesis and catalytic efficiency of four new C2 hybrid PTC catalysts and their saturated analogues with reduced double bond. These eight novel hybrid catalysts can be straightforwardly synthesized with good yields and high structural design diversity (with various linkers). The catalytic efficiency of our catalysts was systematically investigated using a glycine imine alkylation reaction, carried out under PTC conditions. It was found that saturated catalysts show both higher reaction yield (up to 98%) and enantioselectivity (up to 94%ee).
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available