Related references
Note: Only part of the references are listed.Boron neutron capture therapy (BNCT): a unique role in radiotherapy with a view to entering the accelerator-based BNCT era
Minoru Suzuki
INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY (2020)
Variations in common diseases, hospital admissions, and deaths in middle-aged adults in 21 countries from five continents (PURE): a prospective cohort study
Gilles R. Dagenais et al.
LANCET (2020)
Selective Neuropeptide Y Conjugates with Maximized Carborane Loading as Promising Boron Delivery Agents for Boron Neutron Capture Therapy
Dennis J. Worm et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
A Selective Carborane-Functionalized Gastrin-Releasing Peptide Receptor Agonist as Boron Delivery Agent for Boron Neutron Capture Therapy
Paul Hoppenz et al.
JOURNAL OF ORGANIC CHEMISTRY (2020)
Antibody-Prodrug Conjugates with KSP Inhibitors and Legumain-Mediated Metabolite Formation
Hans-Georg Lerchen et al.
CHEMISTRY-A EUROPEAN JOURNAL (2019)
Active Targeting Strategies Using Biological Ligands for Nanoparticle Drug Delivery Systems
Jihye Yoo et al.
CANCERS (2019)
Antibody-drug conjugates for cancer
Cindy H. Chau et al.
LANCET (2019)
Identification and stabilization of a highly selective gastrin-releasing peptide receptor agonist
Paul Hoppenz et al.
JOURNAL OF PEPTIDE SCIENCE (2019)
Cancer statistics, 2019
Rebecca L. Siegel et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2019)
Development of EGFR-targeted evodiamine nanoparticles for the treatment of colorectal cancer
Chunpu Li et al.
BIOMATERIALS SCIENCE (2019)
Intracellular target delivery of cell-penetrating peptide-conjugated dodecaborate for boron neutron capture therapy (BNCT)
Ikuhiko Nakase et al.
CHEMICAL COMMUNICATIONS (2019)
Next generation antibody drugs: pursuit of the 'high-hanging fruit'
Paul J. Carter et al.
NATURE REVIEWS DRUG DISCOVERY (2018)
On the design principles of peptide-drug conjugates for targeted drug delivery to the malignant tumor site
Eirinaios I. Vrettos et al.
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY (2018)
Peptide chemistry toolbox - Transforming natural peptides into peptide therapeutics
Milos Erak et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2018)
Glutathione metabolism in cancer progression and treatment resistance
Ankita Bansal et al.
JOURNAL OF CELL BIOLOGY (2018)
GE11-Directed Functional Polymersomal Doxorubicin as an Advanced Alternative to Clinical Liposomal Formulation for Ovarian Cancer Treatment
Yan Zou et al.
MOLECULAR PHARMACEUTICS (2018)
G Protein-Coupled Receptors as Targets for Approved Drugs: How Many Targets and How Many Drugs?
Krishna Sriram et al.
MOLECULAR PHARMACOLOGY (2018)
Applications of Cancer Cell-Specific Aptamers in Targeted Delivery of Anticancer Therapeutic Agents
Minhee Kim et al.
MOLECULES (2018)
Advances in targeting the folate receptor in the treatment/imaging of cancers
Marcos Fernandez et al.
CHEMICAL SCIENCE (2018)
Aptamers in the Therapeutics and Diagnostics Pipelines
Harleen Kaur et al.
THERANOSTICS (2018)
GPCRomics: GPCR Expression in Cancer Cells and Tumors Identifies New, Potential Biomarkers and Therapeutic Targets
Paul A. Insel et al.
FRONTIERS IN PHARMACOLOGY (2018)
The Molecular Basis of G Protein-Coupled Receptor Activation
William I. Weis et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 87 (2018)
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
Freddie Bray et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2018)
A stable meta-carborane enables the generation of boron-rich peptide agonists targeting the ghrelin receptor
Dennis J. Worm et al.
JOURNAL OF PEPTIDE SCIENCE (2018)
The Role of Neuropeptide Y in Cardiovascular Health and Disease
Cheryl M. J. Tan et al.
FRONTIERS IN PHYSIOLOGY (2018)
Boron delivery agents for neutron capture therapy of cancer
Rolf F. Barth et al.
CANCER COMMUNICATIONS (2018)
A realistic appraisal of boron neutron capture therapy as a cancer treatment modality
Rolf F. Barth et al.
CANCER COMMUNICATIONS (2018)
Peptide Receptor Radionuclide Therapy and the Treatment of Gastroentero-pancreatic Neuroendocrine Tumors: Current Findings and Future Perspectives
Nader Hirmas et al.
NUCLEAR MEDICINE AND MOLECULAR IMAGING (2018)
Radiation induced secondary malignancies: a review article
Chinna Babu Dracham et al.
RADIATION ONCOLOGY JOURNAL (2018)
A Promising Therapeutic Target for Metabolic Diseases: Neuropeptide Y Receptors in Humans
Min Yi et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018)
Towards antibody-drug conjugates and prodrug strategies with extracellular stimuli-responsive drug delivery in the tumor microenvironment for cancer therapy
Nicolas Joubert et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
Marked for death: targeting epigenetic changes in cancer
Sophia Xiao Pfister et al.
NATURE REVIEWS DRUG DISCOVERY (2017)
Phase 3 Trial of 177Lu-Dotatate for Midgut Neuroendocrine Tumors
J. Strosberg et al.
NEW ENGLAND JOURNAL OF MEDICINE (2017)
Improving radiotherapy in cancer treatment: Promises and challenges
Helen H. W. Chen et al.
ONCOTARGET (2017)
The Role of Gonadotropin-Releasing Hormone in Cancer Cell Proliferation and Metastasis
Carsten Gruendker et al.
FRONTIERS IN ENDOCRINOLOGY (2017)
GPCRs: Emerging anti-cancer drug targets
Ainhoa Nieto Gutierrez et al.
CELLULAR SIGNALLING (2017)
A Comprehensive Evaluation of the Activity and Selectivity Profile of Ligands for RGD-binding Integrins
Tobias G. Kapp et al.
SCIENTIFIC REPORTS (2017)
A Phase II Trial of AEZS-108 in Castration- and Taxane-Resistant Prostate Cancer
Steven S. Yu et al.
CLINICAL GENITOURINARY CANCER (2017)
EGFR-targeted multifunctional polymersomal doxorubicin induces selective and potent suppression of orthotopic human liver cancer in vivo
Yuan Fang et al.
ACTA BIOMATERIALIA (2017)
Targeting Legumain As a Novel Therapeutic Strategy in Cancers
Chun-Wai Mai et al.
CURRENT DRUG TARGETS (2017)
Peptide-based imaging agents for cancer detection
Xiaolian Sun et al.
ADVANCED DRUG DELIVERY REVIEWS (2017)
Smart linkers in polymer-drug conjugates for tumor-targeted delivery
Minglu Chang et al.
JOURNAL OF DRUG TARGETING (2016)
Structure and function of legumain in health and disease
Elfriede Dall et al.
BIOCHIMIE (2016)
Synthesis, biological studies and molecular dynamics of new anticancer RGD-based peptide conjugates for targeted drug delivery
Y. Gilad et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2016)
Dual-drug RGD conjugates provide enhanced cytotoxicity to melanoma and non-small lung cancer cells
Y. Gilad et al.
BIOPOLYMERS (2016)
Charge-Compensated Metallacarborane Building Blocks for Conjugation with Peptides
Rene Frank et al.
CHEMBIOCHEM (2016)
Bombesin related peptides/receptors and their promising therapeutic roles in cancer imaging, targeting and treatment
Paola Moreno et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2016)
A novel, anisamide-targeted cyclodextrin nanoformulation for siRNA delivery to prostate cancer cells expressing the sigma-1 receptor
Kathleen A. Fitzgerald et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2016)
Activatable iRGD-based peptide monolith: Targeting, internalization, and fluorescence activation for precise tumor imaging
Hong-Jun Cho et al.
JOURNAL OF CONTROLLED RELEASE (2016)
Double Methotrexate-Modified Neuropeptide Y Analogues Express Increased Toxicity and Overcome Drug Resistance in Breast Cancer Cells
David Boehme et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Dose Deposits from 90Y, 177Lu, 111In, and 161Tb in Micrometastases of Various Sizes: Implications for Radiopharmaceutical Therapy
Elif Hindie et al.
JOURNAL OF NUCLEAR MEDICINE (2016)
Innovative chemical synthesis and conformational hints on the lipopeptide liraglutide
Ivan Guryanov et al.
JOURNAL OF PEPTIDE SCIENCE (2016)
Effects of antibody, drug and linker on the preclinical and clinical toxicities of antibody-drug conjugates
Heather Donaghy
MABS (2016)
Small Molecules for Active Targeting in Cancer
Chin S. Kue et al.
MEDICINAL RESEARCH REVIEWS (2016)
Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes
Steven P. Marso et al.
NEW ENGLAND JOURNAL OF MEDICINE (2016)
Design and characteristics of cytotoxic fibroblast growth factor 1 conjugate for fibroblast growth factor receptor-targeted cancer therapy
Anna Szlachcic et al.
DRUG DESIGN DEVELOPMENT AND THERAPY (2016)
Fundamentals of cancer metabolism
Ralph J. DeBerardinis et al.
SCIENCE ADVANCES (2016)
Present status of Accelerator-Based BNCT
Andres Juan Kreiner et al.
REPORTS OF PRACTICAL ONCOLOGY AND RADIOTHERAPY (2016)
Tumor-specific delivery of BSH-3R for boron neutron capture therapy and positron emission tomography imaging in a mouse brain tumor model
Yoshiya Iguchi et al.
BIOMATERIALS (2015)
Peptide Receptor Radionuclide Therapy: An Overview
Ashutosh Dash et al.
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS (2015)
Controlling Toxicity of Peptide-Drug Conjugates by Different Chemical Linker Structures
David Boehme et al.
CHEMMEDCHEM (2015)
Cell penetrating peptides improve tumor delivery of cargos through neuropilin-1-dependent extravasation
Tetsuya Kadonosono et al.
JOURNAL OF CONTROLLED RELEASE (2015)
Synthesis and in Vitro and in Vivo Evaluation of an 18F-Labeled Neuropeptide Y Analogue for Imaging of Breast Cancer by PET
Sven Hofmann et al.
MOLECULAR PHARMACEUTICS (2015)
Synthesis and characterization of Bombesin-superparamagnetic iron oxide nanoparticles as a targeted contrast agent for imaging of breast cancer using MRI
Atefeh Jafari et al.
NANOTECHNOLOGY (2015)
Targeting the translation machinery in cancer
Mamatha Bhat et al.
NATURE REVIEWS DRUG DISCOVERY (2015)
Silencing Gastrin-Releasing Peptide Receptor Suppresses Key Regulators of Aerobic Glycolysis in Neuroblastoma Cells
Eric J. Rellinger et al.
PEDIATRIC BLOOD & CANCER (2015)
Advancements in Tumor Targeting Strategies for Boron Neutron Capture Therapy
Micah John Luderer et al.
PHARMACEUTICAL RESEARCH (2015)
GRPR-targeted Protein Contrast Agents for Molecular Imaging of Receptor Expression in Cancers by MRI
Fan Pu et al.
SCIENTIFIC REPORTS (2015)
Paclitaxel Through the Ages of Anticancer Therapy: Exploring Its Role in Chemoresistance and Radiation Therapy
Anna Maria Barbuti et al.
CANCERS (2015)
Immunogenicity of Antibody Drug Conjugates: Bioanalytical Methods and Monitoring Strategy for a Novel Therapeutic Modality
M. Benjamin Hock et al.
AAPS JOURNAL (2015)
Receptor-Mediated Uptake of Boron-Rich Neuropeptide Y Analogues for Boron Neutron Capture Therapy
Verena M. Ahrens et al.
CHEMMEDCHEM (2015)
Neuropeptide Y receptors: a promising target for cancer imaging and therapy
Juan Li et al.
REGENERATIVE BIOMATERIALS (2015)
Automated solid-phase peptide synthesis to obtain therapeutic peptides
Veronika Maede et al.
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY (2014)
The acceleration of boron neutron capture therapy using multi-linked mercaptoundecahydrododecaborate (BSH) fused cell-penetrating peptide
Hiroyuki Michiue et al.
BIOMATERIALS (2014)
A phase 1 and dose-finding study of LY2523355 (litronesib), an Eg5 inhibitor, in Japanese patients with advanced solid tumors
Hiroshi Wakui et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2014)
Targeted Chemotherapy with Metal Complexes
Alyson G. Weidmann et al.
COMMENTS ON INORGANIC CHEMISTRY (2014)
Vasoactive intestinal peptide receptor- based imaging and treatment of tumors ( Review)
Bo Tang et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2014)
Controlled release of free doxorubicin from peptide-drug conjugates by drug loading
Zhipeng Chen et al.
JOURNAL OF CONTROLLED RELEASE (2014)
Cell-Penetrating, Guanidinium-Rich Molecular Transporters for Overcoming Efflux-Mediated Multidrug Resistance
Jessica R. Vargas et al.
MOLECULAR PHARMACEUTICS (2014)
Receptor-targeted drug delivery: current perspective and challenges
Imran Vhora et al.
THERAPEUTIC DELIVERY (2014)
1,2,3-Triazoles as Amide Bond Mimics: Triazole Scan Yields Protease-Resistant Peptidomimetics for Tumor Targeting
Ibai E. Valverde et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2013)
Enzyme-activated nanoconjugates for tunable release of doxorubicin in hepatic cancer cells
Scott H. Medina et al.
BIOMATERIALS (2013)
Targeted delivery of doxorubicin through conjugation with EGF receptor-binding peptide overcomes drug resistance in human colon cancer cells
Shibin Ai et al.
BRITISH JOURNAL OF PHARMACOLOGY (2013)
Acidic extracellular microenvironment and cancer
Yasumasa Kato et al.
CANCER CELL INTERNATIONAL (2013)
Phase I Study of GRN1005 in Recurrent Malignant Glioma
Jan Drappatz et al.
CLINICAL CANCER RESEARCH (2013)
An Update of Radiolabeled Bombesin Analogs for Gastrin-Releasing Peptide Receptor Targeting
Zilin Yu et al.
CURRENT PHARMACEUTICAL DESIGN (2013)
Advances in the discovery of kinesin spindle protein (Eg5) inhibitors as antitumor agents
Hala Bakr El-Nassan
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2013)
Cathepsin B as a cancer target
Christopher S. Gondi et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2013)
Synergistic co-delivery of doxorubicin and paclitaxel using multi-functional micelles for cancer treatment
Hoang Hanh Phuoc Duong et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2013)
Tunable Thioesters as Reduction Responsive Functionality for Traceless Reversible Protein PEGylation
Jianwei Chen et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)
Synthesis of Peptide Radiopharmaceuticals for the Therapy and Diagnosis of Tumor Diseases
Mazen Jamous et al.
MOLECULES (2013)
Targeting GRPR in urological cancers -from basic research to clinical application
Rosalba Mansi et al.
NATURE REVIEWS UROLOGY (2013)
Immunogenicity assays for antibody-drug conjugates: case study with ado-trastuzumab emtansine
Montserrat Carrasco-Triguero et al.
BIOANALYSIS (2013)
A review of the use of somatostatin analogs in oncology
Ozge Keskin et al.
ONCOTARGETS AND THERAPY (2013)
Neurotensin and its high affinity receptor 1 as a potential pharmacological target in cancer therapy
Zherui Wu et al.
Frontiers in Endocrinology (2013)
Neuropeptide Y receptors: how to get subtype selectivity
Xavier Pedragosa-Badia et al.
Frontiers in Endocrinology (2013)
Disulfide Linkage: A Potent Strategy in Tumor-Targeting Drug Discovery
J. Wang et al.
CURRENT MEDICINAL CHEMISTRY (2012)
Converting Peptides into Drug Leads by Lipidation
L. Zhang et al.
CURRENT MEDICINAL CHEMISTRY (2012)
GnRH Receptors in Cancer: From Cell Biology to Novel Targeted Therapeutic Strategies
Patrizia Limonta et al.
ENDOCRINE REVIEWS (2012)
Targeting the EGFR signaling pathway in cancer therapy
Parthasarathy Seshacharyulu et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2012)
Peptides and peptide conjugates: therapeutics on the upward path
Verena M. Ahrens et al.
FUTURE MEDICINAL CHEMISTRY (2012)
Peptide-modified liposomes for selective targeting of bombesin receptors overexpressed by cancer cells: a potential theranostic agent
Antonella Accardo et al.
INTERNATIONAL JOURNAL OF NANOMEDICINE (2012)
Targeted drug delivery for cancer therapy: the other side of antibodies
Michael A. Firer et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2012)
Synthesis and in vitro cytotoxicity of cis,cis,trans-diamminedichloridodisuccinatoplatinum(IV)-peptide bioconjugates
Luca Gaviglio et al.
METALLOMICS (2012)
Current status of boron neutron capture therapy of high grade gliomas and recurrent head and neck cancer
Rolf F. Barth et al.
RADIATION ONCOLOGY (2012)
Applications of Cell-Penetrating Peptides for Tumor Targeting and Future Cancer Therapies
Jakob Regberg et al.
PHARMACEUTICALS (2012)
The ERBB network: at last, cancer therapy meets systems biology
Yosef Yarden et al.
NATURE REVIEWS CANCER (2012)
Smart Nanocarrier Based on PEGylated Hyaluronic Acid for Cancer Therapy
Ki Young Choi et al.
ACS NANO (2011)
Prodrug-based intracellular delivery of anticancer agents
L. Bildstein et al.
ADVANCED DRUG DELIVERY REVIEWS (2011)
Synthesis and evaluation of cyclic RGD-boron cluster conjugates to develop tumor-selective boron carriers for boron neutron capture therapy
Sadaaki Kimura et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2011)
NPY receptors as potential targets for anti-obesity drug development
Ernie Yulyaningsih et al.
BRITISH JOURNAL OF PHARMACOLOGY (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Carbaboranes as Pharmacophores: Properties, Synthesis, and Application Strategies
Matthias Scholz et al.
CHEMICAL REVIEWS (2011)
The Legumain Protease-Activated Auristatin Prodrugs Suppress Tumor Growth and Metastasis without Toxicity
Krishna Mohan Bajjuri et al.
CHEMMEDCHEM (2011)
Yttrium-90 (90Y) in the principal radionuclide therapies: An efficacy correlation between peptide receptor radionuclide therapy, radioimmunotherapy and transarterial radioembolization therapy. Ten years of experience (1999-2009)
Veronica Goffredo et al.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2011)
Metallic radionuclides in the development of diagnostic and therapeutic radiopharmaceuticals
Sibaprasad Bhattacharyya et al.
DALTON TRANSACTIONS (2011)
Incorporation of ortho-Carbaboranyl-Nε-Modified L-Lysine into Neuropeptide Y Receptor Y1- and Y2-Selective Analogues
Verena M. Ahrens et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
Effective targeted chemotherapy using AEZS-108 (AN-152) for LHRH receptor-positive pancreatic cancers
Carsten Gruendker et al.
ONCOLOGY REPORTS (2011)
Pharmacology and selectivity of various natural and synthetic bombesin related peptide agonists for human and rat bombesin receptors differs
Hirotsugu Uehara et al.
PEPTIDES (2011)
The neuropeptide Y system: Pathophysiological and therapeutic implications in obesity and cancer
Lei Zhang et al.
PHARMACOLOGY & THERAPEUTICS (2011)
Integrin Targeted Delivery of Chemotherapeutics
Kai Chen et al.
THERANOSTICS (2011)
Bombesin Receptor-Mediated Imaging and Cytotoxicity: Review and Current Status
Veronica Sancho et al.
CURRENT DRUG DELIVERY (2011)
Somatostatin Receptor-Targeted Anti-Cancer Therapy
Li-Chun Sun et al.
CURRENT DRUG DELIVERY (2011)
Breast-Cancer Diagnosis by Neuropeptide Y Analogues: From Synthesis to Clinical Application
Irfan U. Khan et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)
Antibody-Drug Conjugates: Linking Cytotoxic Payloads to Monoclonal Antibodies
Laurent Ducry et al.
BIOCONJUGATE CHEMISTRY (2010)
Boron neutron capture therapy for newly diagnosed glioblastoma multiforme: an assessment of clinical potential
K. Skold et al.
BRITISH JOURNAL OF RADIOLOGY (2010)
Insertion of a Lysosomal Enzyme Cleavage Site into the Sequence of a Radiolabeled Neuropeptide Influences Cell Trafficking In Vitro and In Vivo
Syed Ali Raza Naqvi et al.
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS (2010)
Modular Branched Neurotensin Peptides for Tumor Target Tracing and Receptor-Mediated Therapy: A Proof-of-Concept
C. Falciani et al.
CURRENT CANCER DRUG TARGETS (2010)
Synthetic therapeutic peptides: science and market
Patrick Vlieghe et al.
DRUG DISCOVERY TODAY (2010)
Therapeutic potential of neuropeptide Y (NPY) receptor ligands
Shaun P. Brothers et al.
EMBO MOLECULAR MEDICINE (2010)
Somatostatin receptor-based imaging and therapy of gastroenteropancreatic neuroendocrine tumors
Dik J. Kwekkeboom et al.
ENDOCRINE-RELATED CANCER (2010)
A novel method for the detection of antibodies to adalimumab in the presence of drug reveals hidden immunogenicity in rheumatoid arthritis patients
Pauline A. van Schouwenburg et al.
JOURNAL OF IMMUNOLOGICAL METHODS (2010)
Delivering nanomedicine to solid tumors
Rakesh K. Jain et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2010)
Integrins as therapeutic targets: lessons and opportunities
Dermot Cox et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
The safety and side effects of monoclonal antibodies
Trevor T. Hansel et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
Integrins in cancer: biological implications and therapeutic opportunities
Jay S. Desgrosellier et al.
NATURE REVIEWS CANCER (2010)
Preclinical evaluation of properties of a new targeted cytotoxic somatostatin analog, AN-162 (AEZS-124), and its effects on tumor growth inhibition
Stephan Seitz et al.
ANTI-CANCER DRUGS (2009)
Boron neutron capture therapy of EGFR or EGFRvIII positive gliomas using either boronated monoclonal antibodies or epidermal growth factor as molecular targeting agents
W. Yang et al.
APPLIED RADIATION AND ISOTOPES (2009)
A Novel Antitumor Prodrug Platform Designed to Be Cleaved by the Endoprotease Legumain
Liron Stern et al.
BIOCONJUGATE CHEMISTRY (2009)
Tissue-Penetrating Delivery of Compounds and Nanoparticles into Tumors
Kazuki N. Sugahara et al.
CANCER CELL (2009)
Convection enhanced delivery of boronated EGF as a molecular targeting agent for neutron capture therapy of brain tumors
Weilian Yang et al.
JOURNAL OF NEURO-ONCOLOGY (2009)
First selective agonist of the neuropeptide Y-1-receptor with reduced size
Denise Zwanziger et al.
JOURNAL OF PEPTIDE SCIENCE (2009)
The structure and function of G-protein-coupled receptors
Daniel M. Rosenbaum et al.
NATURE (2009)
Peptide-receptor radionuclide therapy for endocrine tumors
Martijn van Essen et al.
NATURE REVIEWS ENDOCRINOLOGY (2009)
Molecular imaging targeting peptide receptors
Margret Schottelius et al.
METHODS (2009)
Peptide receptor imaging of prostate cancer with radiolabelled bombesin analogues
R. P. J. Schroeder et al.
METHODS (2009)
Bifunctional coupling agents for radiolabeling of biornolecules and target-specific delivery of metallic radionuclides
Shuang Liu
ADVANCED DRUG DELIVERY REVIEWS (2008)
The synthesis and chelation chemistry of DOTA-peptide conjugates
Luis M. De Leon-Rodriguez et al.
BIOCONJUGATE CHEMISTRY (2008)
closo-borane conjugated regulatory peptides retain high biological affinity:: Synthesis of closo-borane conjugated Tyr3-octreotate derivatives for BNCT
Thomas Betzel et al.
BIOCONJUGATE CHEMISTRY (2008)
In vitro and in vivo evaluation of doxorubicin conjugates with the divalent peptide E-[c(RGDfK)2] that targets integrin αvβ3
Claudia Ryppa et al.
BIOCONJUGATE CHEMISTRY (2008)
Antitumour activity of ANG1005, a conjugate between paclitaxel and the new brain delivery vector Angiopep-2
A. Regina et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
The epidermal growth factor receptor family: Biology driving targeted therapeutics
M. J. Wieduwilt et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2008)
Prodrug strategies in anticancer chemotherapy
Felix Kratz et al.
CHEMMEDCHEM (2008)
Molecular targeting and treatment of composite EGFR and EGFRvIII-positive gliomas using boronated monoclonal antibodies
Weilian Yang et al.
CLINICAL CANCER RESEARCH (2008)
High expression of neuropeptide Y1 receptors in Ewing sarcoma tumors
Meike Koerner et al.
CLINICAL CANCER RESEARCH (2008)
Peptide-targeted radionuclide therapy for melanoma
Yubin Miao et al.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2008)
Recent progress in the identification and clinical evaluation of inhibitors of the mitotic kinesin KSP
Steven D. Knight et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2008)
Paclitaxel-octreotide conjugates in tumor growth inhibition of A549 human non-small cell lung cancer xenografted into nude mice
Hongchang Shen et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2008)
Epidermal growth factor receptor and cancer: control of oncogenic signalling by endocytosis
Michael Vibo Grandal et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2008)
Bombesin receptor antagonists may be preferable to agonists for tumor targeting
Renzo Cescato et al.
JOURNAL OF NUCLEAR MEDICINE (2008)
Somatostatin, cortistatin and their receptors in tumours
M. Volante et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2008)
International Union of Pharmacology. LXVIII. Mammalian Bombesin Receptors: Nomenclature, Distribution, Pharmacology, Signaling, and Functions in Normal and Disease States
R. T. Jensen et al.
PHARMACOLOGICAL REVIEWS (2008)
Bombesin-related peptides and their receptors: recent advances in their role in physiology and disease states
Nieves Gonzalez et al.
CURRENT OPINION IN ENDOCRINOLOGY DIABETES AND OBESITY (2008)
Paul Ehrlich's magic bullet concept: 100 years of progress
Klaus Strebhardt et al.
NATURE REVIEWS CANCER (2008)
Vasoactive intestinal peptide-camptothecin conjugates inhibit the proliferation of breast cancer cells
Terry W. Moody et al.
PEPTIDES (2007)
Structure-activity study on the LH- and FSH-releasing and anticancer effects of gonadotropin-releasing hormone (GnRH)-III analogs
Magdolna Kovacs et al.
PEPTIDES (2007)
Molecular targeting and treatment of an epidermal growth factor receptor-positive glioma using boronated cetuximab
Gong Wu et al.
CLINICAL CANCER RESEARCH (2007)
NPY receptors in human cancer:: A review of current knowledge
Meike Koerner et al.
PEPTIDES (2007)
Solid-phase peptide synthesis: from standard procedures to the synthesis of difficult sequences
Irene Coin et al.
NATURE PROTOCOLS (2007)
Radiolabeled somatostatin receptor antagonists are preferable to agonists for in vivo peptide receptor targeting of tumors
Mihaela Ginj et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Insights into the mechanism of microtubule stabilization by Taxol
Hui Xiao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Role of radiotherapy in cancer control in low-income and middle-income countries
Michael B. Barton et al.
LANCET ONCOLOGY (2006)
Molecular targeting and treatment of EGFRvIII-positive gliomas using boronated monoclonal antibody L8A4
Weilian Yang et al.
CLINICAL CANCER RESEARCH (2006)
Tumor vascular permeability, accumulation, and penetration of macromolecular drug carriers
MR Dreher et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2006)
In vitro and in vivo antitumor effects of cytotoxic camptothecin-bombesin conjugates are mediated by specific interaction with cellular bombesin receptors
Terry W. Moody et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
Targeted chemotherapy with cytotoxic bombesin analogue AN-215 inhibits growth of experimental human prostate cancers
A Stangelberger et al.
INTERNATIONAL JOURNAL OF CANCER (2006)
Identification and characterization of a novel peptide ligand of epidermal growth factor receptor for targeted delivery of therapeutics
ZH Li et al.
FASEB JOURNAL (2005)
Targeted therapy with a cytotoxic somatostatin analog, AN-238, inhibits growth of human experimental endometrial carcinomas expressing multidrug resistance protein MDR-1
JB Engel et al.
CANCER (2005)
Receptors for luteinizing hormone releasing hormone (LHRH) expressed in human non-Hodgkin's lymphomas can be targeted for therapy with the cytotoxic LHRH analogue AN-207
G Keller et al.
EUROPEAN JOURNAL OF CANCER (2005)
Boron neutron capture therapy of cancer: Current status and future prospects
RF Barth et al.
CLINICAL CANCER RESEARCH (2005)
Membrane destabilizing properties of cell-penetrating peptides
PEG Thorén et al.
BIOPHYSICAL CHEMISTRY (2005)
177Lu-antibody conjugates for single-cell kill of B-lymphoma cells in vitro and for therapy of micrometastases in vivo
RB Michel et al.
NUCLEAR MEDICINE AND BIOLOGY (2005)
Protein drug stability: A formulation challenge
S Frokjaer et al.
NATURE REVIEWS DRUG DISCOVERY (2005)
Intracellular protein degradation: From a vague idea, through the lysosome and the ubiquitin-proteasome system, and onto human diseases and drug targeting - (Nobel lecture)
A Ciechanover
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2005)
Improving the tumor uptake of 99mTc-labeled neuropeptides using stabilized peptide analogues
P Bläuenstein et al.
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS (2004)
Detection of colon cancer with 99mTc-labeled bombesin derivative (99mTc-leu13-BN1)
F Scopinaro et al.
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS (2004)
Conjugate for efficient delivery of short interfering RNA (siRNA) into mammalian cells
A Muratovska et al.
FEBS LETTERS (2004)
Gonadotropin-releasing hormone and its receptor in normal and malignant cells
GS Harrison et al.
ENDOCRINE-RELATED CANCER (2004)
Conjugation of the closo-borane mereaptoundecahydrododecaborate (BSH) to a tumour selective peptide
W Mier et al.
ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE (2004)
Regulation and function of somatostatin receptors
G Olias et al.
JOURNAL OF NEUROCHEMISTRY (2004)
Anthracyclines: Molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity
G Minotti et al.
PHARMACOLOGICAL REVIEWS (2004)
Development of high affinity camptothecin-bombesin conjugates that have targeted cytotoxicity for bombesin receptor-containing tumor cells
TW Moody et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Biodistribution data from 100 patients i.v. injected with In-111-DTPA-D-Phe(1)-octreotide
E Forssell-Aronsson et al.
ACTA ONCOLOGICA (2004)
Site-specific conjugation of boron-containing dendrimers to anti-EGF receptor monoclonal antibody cetuximab (IMC-C225) and its evaluation as a potential delivery agent for neutron capture therapy
G Wu et al.
BIOCONJUGATE CHEMISTRY (2004)
Synthesis of a Tyr3-octreotate conjugated closo-carborane [HC2B10H10]:: a potential compound for boron neutron capture therapy
E Schirrmacher et al.
TETRAHEDRON LETTERS (2003)
In vitro analysis of stable, receptor-selective neurotensin[8-13] analogues
KP Kokko et al.
JOURNAL OF MEDICINAL CHEMISTRY (2003)
Peptide receptors as molecular targets for cancer diagnosis and therapy
JC Reubi
ENDOCRINE REVIEWS (2003)
Drug delivery strategy utilizing conjugation via reversible disulfide linkages: role and site of cellular reducing activities
G Saito et al.
ADVANCED DRUG DELIVERY REVIEWS (2003)
Selective targeting of tumoral vasculature: Comparison of different formats of an antibody (L19) to the ED-B domain of fibronectin
L Borsi et al.
INTERNATIONAL JOURNAL OF CANCER (2002)
The medicinal chemistry of carboranes
JF Valliant et al.
COORDINATION CHEMISTRY REVIEWS (2002)
Co-expressed peptide receptors in breast cancer as a molecular basis for in vivo multireceptor tumour targeting
JC Reubi et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2002)
In vitro and in vivo evaluation of a 99mTc(I)-labeled bombesin analogue for imaging of gastrin releasing peptide receptor-positive tumors
R La Bella et al.
NUCLEAR MEDICINE AND BIOLOGY (2002)
Nucleoside analogues and nucleobases in cancer treatment
CM Galmarini et al.
LANCET ONCOLOGY (2002)
Cathepsin B-labile dipeptide linkers for lysosomal release of doxorubicin from internalizing immunoconjugates: Model studies of enzymatic drug release and antigen-specific in vitro anticancer activity
GM Dubowchik et al.
BIOCONJUGATE CHEMISTRY (2002)
Technetium labeled bombesin-like peptide: Preliminary report on breast cancer uptake in patients
F Scopinaro et al.
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS (2002)
Indium-111-pentetreotide prolongs survival in gastroenteropancreatic malignancies
LB Anthony et al.
SEMINARS IN NUCLEAR MEDICINE (2002)
Rapid internalization and recycling of the human neuropeptide YY1 receptor
H Gicquiaux et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Homologous regulation of melanocortin-1 receptor (MC1R) expression in melanoma tumor cells in vivo
S Froidevaux et al.
JOURNAL OF RECEPTOR AND SIGNAL TRANSDUCTION RESEARCH (2002)
A peptide carrier for the delivery of biologically active proteins into mammalian cells
MC Morris et al.
NATURE BIOTECHNOLOGY (2001)
Discovery of potent and selective peptide agonists at the GRP-preferring bombesin receptor (BB2)
JG Darker et al.
JOURNAL OF PEPTIDE SCIENCE (2001)
Drug-resistance in human melanoma
H Helmbach et al.
INTERNATIONAL JOURNAL OF CANCER (2001)
Novel analogues of neuropeptide Y with a preference for the Y1-receptor
RM Söll et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2001)
Novel peptide conjugates for tumor-specific chemotherapy
M Langer et al.
JOURNAL OF MEDICINAL CHEMISTRY (2001)
Ligand binding to integrins
EF Plow et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Targeting delivery of paclitaxel into tumor cells via somatostatin receptor endocytosis
CM Huang et al.
CHEMISTRY & BIOLOGY (2000)
Immunotoxicity of ethyl carbamate in female BALB/c mice: role of esterase and cytochrome P450
SW Cha et al.
TOXICOLOGY LETTERS (2000)
High incidence of receptors for luteinizing hormone-releasing hormone (LHRH) and LHRH receptor gene expression in human prostate cancers
G Halmos et al.
JOURNAL OF UROLOGY (2000)