Journal
PHOTONICS RESEARCH
Volume 8, Issue 7, Pages 1253-1259Publisher
OPTICAL SOC AMER
DOI: 10.1364/PRJ.396135
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Funding
- Croucher Foundation [CM/CT/CF/CIA/0688/19ay]
- Chinese University of Hong Kong Direct Research Grant
- Shun Hing Institute of Advanced Engineering [BME-p3-18]
- Innovation and Technology Commission Hong Kong [ITS/098/18FP, ITS/394/17]
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Quantitative phase microscopy (QPM) has emerged as an important tool for material metrology and biological imaging. For broader adoption in those applications, we have proposed and demonstrated a new portable off-axis QPM method, which works in both transmission and reflection modes to meet different sample measurement requirements. The temporal and spatial sensitivities of our system, as quantified by optical path-length difference values, are 0.65 nm and 1.04 nm, respectively. To demonstrate its applicability for a wide range of applications, we deployed our system for profiling transistor gold electrode samples, observing red blood cell membrane fluctuations, imaging living cells flowing in a microfluidic chip, etc. Our portable QPM system has a low-cost design and involves a simple and robust phase-retrieval algorithm that we envision will allow for broader deployment at different environmental settings, including in resource-limited sites and integration with other metrology or imaging modalities. (c) 2020 Chinese Laser Press
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