Related references
Note: Only part of the references are listed.Epigenetic regulation of COX-2 expression by DNA hypomethylation via NF-κB activation in ketamine-induced ulcerative cystitis
Shu-Mien Chuang et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2019)
Brain pyrimidine nucleotide synthesis and Alzheimer disease
Alba Pesini et al.
AGING-US (2019)
Cold-induced lipid dynamics and transcriptional programs in white adipose tissue
Ziye Xu et al.
BMC BIOLOGY (2019)
The Role of Leptin and Adiponectin in Obesity-Associated Cognitive Decline and Alzheimer's Disease
Leticia Forny-Germano et al.
FRONTIERS IN NEUROSCIENCE (2019)
Tau and mTOR: The Hotspots for Multifarious Diseases in Alzheimer's Development
Zeba Mueed et al.
FRONTIERS IN NEUROSCIENCE (2019)
Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts
Juho Tynkkynen et al.
ALZHEIMERS & DEMENTIA (2018)
COX-2 expression mediated by calcium-TonEBP signaling axis under hyperosmotic conditions serves osmoprotective function in nucleus pulposus cells
Hyowon Choi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Autophagy and Alzheimer's Disease: From Molecular Mechanisms to Therapeutic Implications
Md. Sahab Uddin et al.
FRONTIERS IN AGING NEUROSCIENCE (2018)
Synopsis of arachidonic acid metabolism: A review
Violette Said Hanna et al.
JOURNAL OF ADVANCED RESEARCH (2018)
Adipose mTORC1 Suppresses Prostaglandin Signaling and Beige Adipogenesis via the CRTC2-COX-2 Pathway
Xing Zhang et al.
CELL REPORTS (2018)
Insulin Resistance in Alzheimer's Disease
Lais S. S. Ferreira et al.
FRONTIERS IN NEUROSCIENCE (2018)
The Trojan horse - neuroinflammatory impact of T cells in neurodegenerative diseases
Annika Sommer et al.
MOLECULAR NEURODEGENERATION (2017)
mTOR inhibition improves the immunomodulatory properties of human bone marrow mesenchymal stem cells by inducing COX-2 and PGE2
Binsheng Wang et al.
STEM CELL RESEARCH & THERAPY (2017)
Purine Nucleotide Availability Regulates mTORC1 Activity through the Rheb GTPase
Natasha Emmanuel et al.
CELL REPORTS (2017)
The mTORC1 Signaling Network Senses Changes in Cellular Purine Nucleotide Levels
Gerta Hoxhaj et al.
CELL REPORTS (2017)
Divergent Metabolic Regulation of Autophagy and mTORC1-Early Events in Alzheimer's Disease?
Mai A. Shafei et al.
FRONTIERS IN AGING NEUROSCIENCE (2017)
p70 S6 Kinase and Tau in Alzheimer's Disease
Jin-Jing Pei et al.
JOURNAL OF ALZHEIMERS DISEASE (2017)
mTOR Signaling in Growth, Metabolism, and Disease
Robert A. Saxton et al.
CELL (2017)
PAT4 levels control amino-acid sensitivity of rapamycin-resistant mTORC1 from the Golgi and affect clinical outcome in colorectal cancer
S-J Fan et al.
ONCOGENE (2016)
Inverse relationship between Alzheimer's disease and cancer, and other factors contributing to Alzheimer's disease: a systematic review
Ovais Shafi
BMC NEUROLOGY (2016)
Amino Acid Sensing bymTORC1: Intracellular Transporters Mark the Spot
Deborah C. I. Goberdhan et al.
CELL METABOLISM (2016)
Rapamycin Blocks Induction of the Thermogenic Program in White Adipose Tissue
Cassie M. Tran et al.
DIABETES (2016)
The tumor suppressor FLCN mediates an alternate mTOR pathway to regulate browning of adipose tissue
Shogo Wada et al.
GENES & DEVELOPMENT (2016)
Cross-interactions between the Alzheimer Disease Amyloid-β Peptide and Other Amyloid Proteins: A Further Aspect of the Amyloid Cascade Hypothesis
Jinghui Luo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Activation of mTORC1 is essential for β-adrenergic stimulation of adipose browning
Dianxin Liu et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
An evolutionarily conserved pathway controls proteasome homeostasis
Adrien Rousseau et al.
NATURE (2016)
Alzheimer's disease-like pathology has transient effects on the brain and blood metabolome
Xiaobei Pan et al.
NEUROBIOLOGY OF AGING (2016)
TOR Complexes and the Maintenance of Cellular Homeostasis
Sandra Eltschinger et al.
TRENDS IN CELL BIOLOGY (2016)
mTORC1-mediated downregulation of COX2 restrains tumor growth caused by TSC2 deficiency
Hongwu Li et al.
ONCOTARGET (2016)
mTor mediates tau localization and secretion: Implication for Alzheimer's disease
Zhi Tang et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2015)
Prognostic impact of COX-2 in non-small cell lung cancer: A comprehensive compartment-specific evaluation of tumor and stromal cell expression
Johanna S. M. Mattsson et al.
CANCER LETTERS (2015)
Physiology of the Alzheimer's disease
Jung Y. Hahr
MEDICAL HYPOTHESES (2015)
mTOR signaling in aging and neurodegeneration: At the crossroad between metabolism dysfunction and impairment of autophagy
Marzia Perluigi et al.
NEUROBIOLOGY OF DISEASE (2015)
mTOR inhibition activates overall protein degradation by the ubiquitin proteasome system as well as by autophagy
Jinghui Zhao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Differential regulation of mTORC1 by leucine and glutamine
Jenna L. Jewell et al.
SCIENCE (2015)
Mammalian Target of Rapamycin Inhibitors and Life-Threatening Conditions in Tuberous Sclerosis Complex
Romina Moavero et al.
SEMINARS IN PEDIATRIC NEUROLOGY (2015)
Ablation of PRDM16 and Beige Adipose Causes Metabolic Dysfunction and a Subcutaneous to Visceral Fat Switch
Paul Cohen et al.
CELL (2014)
Grb10 Promotes Lipolysis and Thermogenesis by Phosphorylation-Dependent Feedback Inhibition of mTORC1
Meilian Liu et al.
CELL METABOLISM (2014)
Indomethacin Treatment Prevents High Fat Diet-induced Obesity and Insulin Resistance but Not Glucose Intolerance in C57BL/6J Mice
Even Fjaere et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
SOUVENAID®: A NEW APPROACH TO MANAGEMENT OF EARLY ALZHEIMER'S DISEASE
C. W. Ritchie et al.
JOURNAL OF NUTRITION HEALTH & AGING (2014)
Molecular Basis of Giant Cells in Tuberous Sclerosis Complex
David J. Kwiatkowski et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Post-translational regulation of COX2 activity by FYN in prostate cancer cells
Anna Alexanian et al.
ONCOTARGET (2014)
Rationale and clinical data supporting nutritional intervention in Alzheimer's disease
S. Engelborghs et al.
ACTA CLINICA BELGICA (2014)
Nutrient sensing via mTOR in T cells maintains a tolerogenic microenvironment
Duncan Howie et al.
FRONTIERS IN IMMUNOLOGY (2014)
Resolution of inflammation: an integrated view
Almudena Ortega-Gomez et al.
EMBO MOLECULAR MEDICINE (2013)
mTOR kinase, a key player in the regulation of glial functions: Relevance for the therapy of multiple sclerosis
Cinzia Dello Russo et al.
GLIA (2013)
Mammalian Target of Rapamycin (mTor) Mediates Tau Protein Dyshomeostasis IMPLICATION FOR ALZHEIMER DISEASE
Zhi Tang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Alzheimer's disease and insulin resistance: translating basic science into clinical applications
Fernanda G. De Felice
JOURNAL OF CLINICAL INVESTIGATION (2013)
Brown and beige fat: development, function and therapeutic potential
Matthew Harms et al.
NATURE MEDICINE (2013)
Stimulation of de Novo Pyrimidine Synthesis by Growth Signaling Through mTOR and S6K1
Issam Ben-Sahra et al.
SCIENCE (2013)
mTOR Signaling in Growth Control and Disease
Mathieu Laplante et al.
CELL (2012)
mTOR Inhibition Prevents Epithelial Stem Cell Senescence and Protects from Radiation-Induced Mucositis
Ramiro Iglesias-Bartolome et al.
CELL STEM CELL (2012)
The PI3K/AKT/mTOR Pathway as a Therapeutic Target in Endometrial Cancer
Brian M. Slomovitz et al.
CLINICAL CANCER RESEARCH (2012)
TBC1D7 Is a Third Subunit of the TSC1-TSC2 Complex Upstream of mTORC1
Christian C. Dibble et al.
MOLECULAR CELL (2012)
A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
Pontus Bostroem et al.
NATURE (2012)
Amino acids and mTORC1: from lysosomes to disease
Alejo Efeyan et al.
TRENDS IN MOLECULAR MEDICINE (2012)
Mechanisms of Resolution of Inflammation A Focus on Cardiovascular Disease
Benjamin H. Maskrey et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2011)
Tuberous sclerosis complex: tumors and tumorigenesis
Julita Borkowska et al.
INTERNATIONAL JOURNAL OF DERMATOLOGY (2011)
Inducing Autophagy by Rapamycin Before, but Not After, the Formation of Plaques and Tangles Ameliorates Cognitive Deficits
Smita Majumder et al.
PLOS ONE (2011)
Mammalian Target of Rapamycin Protein Complex 2 Regulates Differentiation of Th1 and Th2 Cell Subsets via Distinct Signaling Pathways
Keunwook Lee et al.
IMMUNITY (2010)
Phospholipases A2 and Inflammatory Responses in the Central Nervous System
Grace Y. Sun et al.
NEUROMOLECULAR MEDICINE (2010)
Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-beta Levels in a Mouse Model of Alzheimer's Disease
Patricia Spilman et al.
PLOS ONE (2010)
Hypertonic induction of COX2 expression requires TonEBP/NFAT5 in renal epithelial cells
N. O. Favale et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
The COX-2/PGE(2) pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment
Alexander Greenhough et al.
CARCINOGENESIS (2009)
A Common Biological Mechanism in Cancer and Alzheimer's Disease?
M. I. Behrens et al.
CURRENT ALZHEIMER RESEARCH (2009)
Phospholipase A2 structure/function, mechanism, and signaling
John E. Burke et al.
JOURNAL OF LIPID RESEARCH (2009)
Prostanoids in health and disease
Emer M. Smyth et al.
JOURNAL OF LIPID RESEARCH (2009)
Cyclooxygenases: structural and functional insights
Carol A. Rouzer et al.
JOURNAL OF LIPID RESEARCH (2009)
Cyclooxygenase 2 mediates the antiangiogenic effect of rapamycin in Ewing sarcoma
Aaron M. Lipskar et al.
JOURNAL OF PEDIATRIC SURGERY (2009)
The PI3K-Akt-mTOR pathway regulates Aβ oligomer induced neuronal cell cycle events
Kiran Bhaskar et al.
MOLECULAR NEURODEGENERATION (2009)
Cyclooxygenase-2 inhibition improves amyloid-β-mediated suppression of memory and synaptic plasticity
Linda A. Kotilinek et al.
BRAIN (2008)
Adipose-Specific Knockout of raptor Results in Lean Mice with Enhanced Mitochondrial Respiration
Pazit Polak et al.
CELL METABOLISM (2008)
Cyclooxygenase-1 and-2 in the different stages of Alzheimer's disease pathology
J. J. M. Hoozemans et al.
CURRENT PHARMACEUTICAL DESIGN (2008)
The autophagy-lysosomal degradation pathway: role in neurodegenerative disease and therapy
John J. Shacka et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2008)
Molecular target therapies in endometrial cancer: From the basic research to the clinic
Angiolo Gadducci et al.
GYNECOLOGICAL ENDOCRINOLOGY (2008)
Overexpression of COX-2 gene in oral cancer is independent of stage of disease and degree of differentiation
M. Pandey et al.
INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY (2008)
mTOR-dependent signalling in Alzheimer's disease
Jin-Jing Pei et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2008)
T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR
Stephan Sauer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
cAMP-dependent signaling regulates the adipogenic effect of n-6 polyunsaturated fatty acids
Lise Madsen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Mesenchymal stem cells inhibit natural killer-cell proliferation, cytotoxicity, and cytokine production: role of indoleamine 2,3-dioxygenase and prostaglandin E2
Grazia Maria Spaggiari et al.
BLOOD (2008)
Hypertonic-induced lamin A/C synthesis and distribution to nucleoplasmic speckles is mediated by TonEBP/NFAT5 transcriptional activator
Nicolas O. Favale et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Cellular response to hyperosmotic stresses
Maurice B. Burg et al.
PHYSIOLOGICAL REVIEWS (2007)
Arachidonic acid potentiates exocytosis and allows neuronal SNARE complex to interact with Munc18a
Catherine F. Latham et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin
Thuy L. Phung et al.
CANCER CELL (2006)
Neuroinflammation and regeneration in the early stages of Alzheimer's disease pathology
JJM Hoozemans et al.
INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE (2006)
Role of osmolytes as chemical chaperones during the refolding of aminoacylase
SH Kim et al.
BIOCHEMISTRY AND CELL BIOLOGY (2006)
Macroautophagy -: a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease
WH Yu et al.
JOURNAL OF CELL BIOLOGY (2005)
Autophagy and aging -: The importance of maintaining clean cells
Ana Maria Cuervo et al.
AUTOPHAGY (2005)
PAT-related amino acid transporters regulate growth via a novel mechanism that does not require bulk transport of amino acids
DCI Goberdhan et al.
DEVELOPMENT (2005)
Cyclooxygenase 2 plays a pivotal role in the resolution of acute lung injury
K Fukunaga et al.
JOURNAL OF IMMUNOLOGY (2005)
Increased activation of the mammalian target of rapamycin pathway in liver and skeletal muscle of obese rats: Possible involvement in obesity-linked insulin resistance
L Khamzina et al.
ENDOCRINOLOGY (2005)
Neuronal COX-2 expression and phosphorylation of pRb precede p38 MAPK activation and neurofibrillary changes in AD temporal cortex
JJM Hoozemans et al.
NEUROBIOLOGY OF DISEASE (2004)
Incipient Alzheimer's disease: Microarray correlation analyses reveal major transcriptional and tumor suppressor responses
EM Blalock et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Hypertonic stress activates glycogen synthase kinase 3β-mediated apoptosis of renal medullary interstitial cells, suppressing an NFκB-driven cyclooxygenase-2-dependent survival pathway
R Rao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity
SH Um et al.
NATURE (2004)
Cyclooxygenase-2 (COX-2) in inflammatory and degenerative brain diseases
L Minghetti
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2004)
Transcriptional regulation of cyclooxygenase-2 gene in pancreatic β-cells
F Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Cyclooxygenase-2 activity contributes to neuronal expression of cyclin D1 after anoxia/ischemia in vitro and in vivo
RW Chen et al.
MOLECULAR BRAIN RESEARCH (2004)
Peroxisome proliferator-activated receptor γ induces a clearance mechanism for the amyloid-β peptide
IE Camacho et al.
JOURNAL OF NEUROSCIENCE (2004)
Promoter methylation regulates cyclooxygenase expression in breast cancer
XR Ma et al.
BREAST CANCER RESEARCH (2004)
Synaptic lipid signaling: significance of polyunsaturated fatty acids and platelet-activating factor
NG Bazan
JOURNAL OF LIPID RESEARCH (2003)
IL-1β mediated up-regulation of HIF-1α via an NFkB/COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesis
YJ Jung et al.
FASEB JOURNAL (2003)
Up-regulation of phosphorylated/activated p70 S6 kinase and its relationship to neurofibrillary pathology in Alzheimer's disease
WL An et al.
AMERICAN JOURNAL OF PATHOLOGY (2003)
NSAIDs and enantiomers of flurbiprofen target γ-secretase and lower Aβ42 in vivo
JL Eriksen et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
COX2 activity promotes organic osmolyte accumulation and adaptation of renal medullary interstitial cells to hypertonic stress
GW Moeckel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Cyclooxygenase-2 biology
J Claria
CURRENT PHARMACEUTICAL DESIGN (2003)
Selective inhibition of Aβ42 production by NSAID R-enantiomers
T Morihara et al.
JOURNAL OF NEUROCHEMISTRY (2002)
The potential of anti-inflammatory drugs for the treatment of Alzheimer's disease
PS Aisen
LANCET NEUROLOGY (2002)
Inflammation in neurodegenerative disease - A double-edged sword
T Wyss-Coray et al.
NEURON (2002)
Prostaglandins and other lipid mediators in Alzheimer's disease
NG Bazan et al.
PROSTAGLANDINS & OTHER LIPID MEDIATORS (2002)
Cyclin D1 and cyclin E are co-localized with cyclo-oxygenase 2 (COX-2) in pyramidal neurons in Alzheimer disease temporal cortex
JJM Hoozemans et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2002)
Cyclooxygenase (COX)-2 and cell cycle activity in a transgenic mouse model of Alzheimer's Disease neuropathology
ZM Xiang et al.
NEUROBIOLOGY OF AGING (2002)
Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor
M Guba et al.
NATURE MEDICINE (2002)
Aberrant methylation and histone deacetylation of cyclooxygenase 2 in gastric cancer
T Kikuchi et al.
INTERNATIONAL JOURNAL OF CANCER (2002)
A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity
S Weggen et al.
NATURE (2001)
Oxidative glutamate toxicity can be a component of the excitotoxicity cascade
D Schubert et al.
JOURNAL OF NEUROSCIENCE (2001)
Hyperphosphorylation induces self-assembly of τ into tangles of paired helical filaments/straight filaments
AD Alonso et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Neuronal cyclooxygenase 2 expression in the hippocampal formation as a function of the clinical progression of Alzheimer disease
L Ho et al.
ARCHIVES OF NEUROLOGY (2001)
Type IIA secretory phospholipase A2 up-regulates cyclooxygenase-2 and amplifies cytokine-mediated prostaglandin production in human rheumatoid synoviocytes
MJ Bidgood et al.
JOURNAL OF IMMUNOLOGY (2000)
MAPK mediation of hypertonicity-stimulated cyclooxygenase-2 expression in renal medullary collecting duct cells
TX Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2
AL Hsu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Transcriptional regulation of the gyclooxygenase-2 gene in activated mast cells
ST Reddy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Cyclooxygenase-2 is induced in microglia during chronic cerebral ischemia in humans
H Tomimoto et al.
ACTA NEUROPATHOLOGICA (2000)
Share Paper
