4.1 Review

Focus on the heterogeneity of amyotrophic lateral sclerosis

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Three-dimensional modeling of human neurodegeneration: brain organoids coming of age

Karl Grenier et al.

MOLECULAR PSYCHIATRY (2020)

Article Cell Biology

Reprogramming fibroblasts and peripheral blood cells from a C9ORF72 patient: A proof-of-principle study

Donatella Bardelli et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2020)

Article Neurosciences

Diagnostic and prognostic values of PBMC proteins in amyotrophic lateral sclerosis

Silvia Luotti et al.

NEUROBIOLOGY OF DISEASE (2020)

Article Clinical Neurology

Changing epidemiology of motor neurone disease in Scotland

Danielle J. Leighton et al.

JOURNAL OF NEUROLOGY (2019)

Review Clinical Neurology

An Overview of MicroRNAs as Biomarkers of ALS

Greig Joilin et al.

FRONTIERS IN NEUROLOGY (2019)

Article Clinical Neurology

Neurofilaments in pre-symptomatic ALS and the impact of genotype

Michael Benatar et al.

AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2019)

Article Clinical Neurology

Refining eligibility criteria for amyotrophic lateral sclerosis clinical trials

Ruben P. A. van Eijk et al.

NEUROLOGY (2019)

Article Clinical Neurology

Younger age of onset in familial amyotrophic lateral sclerosis is a result of pathogenic gene variants, rather than ascertainment bias

Puja R. Mehta et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2019)

Article Multidisciplinary Sciences

Combined Tissue-Fluid Proteomics to Unravel Phenotypic Variability in Amyotrophic Lateral Sclerosis

Emanuela Leoni et al.

SCIENTIFIC REPORTS (2019)

Article Clinical Neurology

A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism

Bart Swinnen et al.

ACTA NEUROPATHOLOGICA (2018)

Article Biochemistry & Molecular Biology

Project MinE: study design and pilot analyses of a large-scale whole-genome sequencing study in amyotrophic lateral sclerosis

Wouter Van Rheenen et al.

EUROPEAN JOURNAL OF HUMAN GENETICS (2018)

Review Clinical Neurology

Neuroimaging in amyotrophic lateral sclerosis: current and emerging uses

Federica Agosta et al.

EXPERT REVIEW OF NEUROTHERAPEUTICS (2018)

Review Genetics & Heredity

ALS Genes in the Genomic Era and their Implications for FTD

Hung Phuoc Nguyen et al.

TRENDS IN GENETICS (2018)

Review Clinical Neurology

Neuroimaging in amyotrophic lateral sclerosis: current and emerging uses

Federica Agosta et al.

EXPERT REVIEW OF NEUROTHERAPEUTICS (2018)

Article Biochemistry & Molecular Biology

Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent

Koki Fujimori et al.

NATURE MEDICINE (2018)

Article Neurosciences

Role of Extracellular Vesicles in Amyotrophic Lateral Sclerosis

Deborah Ferrara et al.

FRONTIERS IN NEUROSCIENCE (2018)

Editorial Material Cell & Tissue Engineering

Taking on the Elephant in the Tissue Culture Room: iPSC Modeling for Sporadic ALS

Brian J. Wainger et al.

CELL STEM CELL (2018)

Article Clinical Neurology

The Swedish motor neuron disease quality registry

Elisa Longinetti et al.

AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2018)

Review Clinical Neurology

Gene discovery in amyotrophic lateral sclerosis: implications for clinical management

Ammar Al-Chalabi et al.

NATURE REVIEWS NEUROLOGY (2017)

Article Clinical Neurology

Military service and the risk of amyotrophic lateral sclerosis: A meta-analysis

Hongfei Tai et al.

JOURNAL OF CLINICAL NEUROSCIENCE (2017)

Article Geriatrics & Gerontology

Structural and functional brain signatures of C9orf72 in motor neuron disease

Federica Agosta et al.

NEUROBIOLOGY OF AGING (2017)

Review Medicine, General & Internal

Amyotrophic Lateral Sclerosis

Robert H. Brown et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Article Neurosciences

Decreased Levels of Foldase and Chaperone Proteins Are Associated with an Early-Onset Amyotrophic Lateral Sclerosis

Melania Filareti et al.

FRONTIERS IN MOLECULAR NEUROSCIENCE (2017)

Review Cell Biology

Modelling amyotrophic lateral sclerosis: progress and possibilities

Philip Van Damme et al.

DISEASE MODELS & MECHANISMS (2017)

Review Clinical Neurology

ALS and FTD: an epigenetic perspective

Veronique V. Belzil et al.

ACTA NEUROPATHOLOGICA (2016)

Article Clinical Neurology

Amyotrophic lateral sclerosis: moving towards a new classification system

Ammar Al-Chalabi et al.

LANCET NEUROLOGY (2016)

Article Multidisciplinary Sciences

Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD

Steven Boeynaems et al.

SCIENTIFIC REPORTS (2016)

Article Clinical Neurology

Association between diabetes and amyotrophic lateral sclerosis in Sweden

D. Mariosa et al.

EUROPEAN JOURNAL OF NEUROLOGY (2015)

Review Neurosciences

Comorbidities in Neurology: Is adenosine the common link?

Detlev Boison et al.

NEUROPHARMACOLOGY (2015)

Article Multidisciplinary Sciences

Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways

Elizabeth T. Cirulli et al.

SCIENCE (2015)

Article Clinical Neurology

Extrapyramidal and cognitive signs in amyotrophic lateral sclerosis: A population based cross-sectional study

Elisabetta Pupillo et al.

AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2015)

Article Biochemistry & Molecular Biology

A novel SOD1-ALS mutation separates central and peripheral effects of mutant SOD1 toxicity

Peter I. Joyce et al.

HUMAN MOLECULAR GENETICS (2015)

Article Clinical Neurology

Plasma neurofilament heavy chain levels and disease progression in amyotrophic lateral sclerosis: insights from a longitudinal study

Ching-Hua Lu et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2015)

Editorial Material Multidisciplinary Sciences

Make mouse studies work

Steve Perrin

NATURE (2014)

Review Neurosciences

State of play in amyotrophic lateral sclerosis genetics

Alan E. Renton et al.

NATURE NEUROSCIENCE (2014)

Review Biotechnology & Applied Microbiology

Neuroimaging to Investigate Multisystem Involvement and Provide Biomarkers in Amyotrophic Lateral Sclerosis

Pierre-Francois Pradat et al.

BIOMED RESEARCH INTERNATIONAL (2014)

Article Clinical Neurology

Prevalence and prognostic impact of comorbidities in amyotrophic lateral sclerosis

S. Koerner et al.

EUROPEAN JOURNAL OF NEUROLOGY (2013)

Review Clinical Neurology

The epidemiology of ALS: a conspiracy of genes, environment and time

Ammar Al-Chalabi et al.

NATURE REVIEWS NEUROLOGY (2013)

Article Clinical Neurology

Multiparametric MRI study of ALS stratified for the C9orf72 genotype

Peter Bede et al.

NEUROLOGY (2013)

Article Multidisciplinary Sciences

Increased Neurofilament Light Chain Blood Levels in Neurodegenerative Neurological Diseases

Johanna Gaiottino et al.

PLOS ONE (2013)

Article Multidisciplinary Sciences

ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43

Eveline S. Arnold et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Review Clinical Neurology

Are professional soccer players at higher risk for ALS?

Ettore Beghi

AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2013)

Article Clinical Neurology

A proposed staging system for amyotrophic lateral sclerosis

Jose C. Roche et al.

BRAIN (2012)

Article Genetics & Heredity

Modelling the Effects of Penetrance and Family Size on Rates of Sporadic and Familial Disease

Ammar Al-Chalabi et al.

HUMAN HEREDITY (2011)

Article Biochemistry & Molecular Biology

Phenotypic Heterogeneity in a SOD1 G93D Italian ALS Family: An Example of Human Model to Study a Complex Disease

Silvana Penco et al.

JOURNAL OF MOLECULAR NEUROSCIENCE (2011)

Article Clinical Neurology

Incidence of amyotrophic lateral sclerosis in Europe

Giancarlo Logroscino et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2010)

Article Clinical Neurology

Treatment with lithium carbonate does not improve disease progression in two different strains of SOD1 mutant mice

Chiara Pizzasegola et al.

AMYOTROPHIC LATERAL SCLEROSIS (2009)

Article Clinical Neurology

Reduced frequency of ALS in an ethnically mixed population

T. Zaldivar et al.

NEUROLOGY (2009)

Article Multidisciplinary Sciences

Lithium delays progression of amyotrophic lateral sclerosis

Francesco Fornai et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Letter Clinical Neurology

Amyotrophic lateral sclerosis in an urban setting - A population based study of inner city London

Clare A. Johnston et al.

JOURNAL OF NEUROLOGY (2006)

Article Clinical Neurology

The G93C mutation in superoxide dismutase 1 -: Clinicopathologic phenotype and prognosis

L Régal et al.

ARCHIVES OF NEUROLOGY (2006)