Journal
POLYMERS
Volume 12, Issue 8, Pages -Publisher
MDPI
DOI: 10.3390/polym12081637
Keywords
3D printing; bioprinting; hydrogel; polyester; peripheral nerve regeneration
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Funding
- Hubei Provincial Natural Science Foundation of China [2016CFB338]
- Wuhan University of technology
- Fundamental Research Funds for the Central Universities (WUT) [WUT: 2020IB030]
- Chinese Thousand Talents Plan Program
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Fabrication of nerve conduits for perfectly repairing or replacing damaged peripheral nerve is an urgent demand worldwide, but it is also a formidable clinical challenge. In the last decade, with the rapid development of manufacture technologies, 3D printing and bioprinting have been becoming remarkable stars in the field of neural engineering. In this review, we explore that the biomaterial inks (hydrogels, thermoplastic, and thermoset polyesters and composite) and bioinks have been selected for 3D printing and bioprinting of peripheral nerve conduits. This review covers 3D manufacturing technologies, including extrusion printing, inkjet printing, stereolithography, and bioprinting with inclusion of cells, bioactive molecules, and drugs. Finally, an outlook on the future directions of 3D printing and 4D printing in customizable nerve therapies is presented.
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