Journal
PLOS BIOLOGY
Volume 18, Issue 7, Pages -Publisher
PUBLIC LIBRARY SCIENCE
DOI: 10.1371/journal.pbio.3000712
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Funding
- National Institute for Health [RO1-NS113048-01]
- University of California, Santa Barbara
- National Science Foundation [NSF PHY-1748958, IOS-1523125, R25GM067110]
- Gordon and Betty Moore Foundation [2919.01]
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Tools enabling closed-loop experiments are crucial to delineate causal relationships between the activity of genetically labeled neurons and specific behaviors. We developed the Raspberry Pi Virtual Reality (PiVR) system to conduct closed-loop optogenetic stimulation of neural functions in unrestrained animals. PiVR is an experimental platform that operates at high temporal resolution (70 Hz) with low latencies (<30 milliseconds), while being affordable (
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