Variability of post-void residual urine volume and bladder voiding efficiency in patients with underactive bladder

Objectives Post-void residual urine volume (PVR) and bladder voiding efficiency (BVE) are widely used as clinical parameters to evaluate patients with voiding dysfunction. The present study was conducted to assess the variability of PVR and BVE determinations in patients with underactive bladder (UAB). In addition, we focused on the bladder volume prior to voiding (BVvoid) that may influence PVR and BVE, and investigated a correlation between PVR and BVvoid, and between BVE and BVvoid. Methods Ten patients with a symptom complex of UAB, who had PVR of 50 mL or greater, were admitted to hospital during a 24-hour period for the measurement of voided volume (VV) and PVR. PVR was measured by transabdominal ultrasonography. BVE was expressed by a fraction (%) of bladder volume evacuated ([VV/BVvoid] x 100). Results Ten patients, five men (mean age of 65.0 years) and five women (mean age of 70.2 years), participated in this study. Regardless of gender, there was a large variation in repeated measurements of PVR in an individual patient. PVR increased with an increase in BVvoid, and there was a significant linear relationship between PVR and BVvoid. BVE was approximately constant after every voiding in each patient, and there was no significant linear relationship between BVE and BVvoid. Conclusions Measurement of PVR was unreliable because of wide variation in the same individual. The variation of BVE was much smaller than PVR. BVE would be a reliable parameter with good reproducibility for the assessment of emptying function.

Automated summary

The study found that there was a large variation in PVR measurements within individual patients with underactive bladder, while the variation of BVE was much smaller. Additionally, the bladder volume prior to voiding (BVvoid) had an impact on PVR but did not show a significant linear relationship with BVE.