Journal
FRONTIERS IN NEUROANATOMY
Volume 14, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fnana.2020.00027
Keywords
apraxia of speech; cerebro-cerebellar loop; motor-speech planning; mutism; tractography
Categories
Funding
- National Natural Science Foundation of China [31540077]
- Science and Technology Planning Project of Guangdong Province, China [2017A030303017]
Ask authors/readers for more resources
While the proximal dentatothalamocortical tracts are considered pivotal in the occurrence of cerebellar mutism syndrome (CMS) after medulloblastoma resection, how the cerebellum participates in motor-speech networks through direct structural connectivity is still unclear.Viatractography, we provide evidence of cerebellar streamlines projecting into the left inferior frontal gyrus majorly connecting Broca's complex and the bilateral Crus lobes. The streamlines, named Crus-Broca tracts, originated from the bilateral Crus lobes, synapsed onto the dentate nucleus, ascended into the superior cerebellar peduncle (where these streamlines were closely superior to the superior border of the supratonsillar cleft and the superolateral roof of the fourth ventricle), surprisingly bypassed the left red nucleus and the left thalamus, and ended at the subregions of Broca's complex. The streamlines, named Broca-Crus tracts, originated from the subregions of Broca's complex and ended predominantly at the right Crus lobes. If verified, the existence of these connections would support the notion of the bilateral cerebellums' participation in motor-speech planning, and the anatomical relationship of Broca-Crus tracts with the supratonsillar cleft would merit consideration for further studies aimed at further elucidating CMS mechanisms.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available