Journal
CLINICS IN LIVER DISEASE
Volume 20, Issue 3, Pages 473-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.cld.2016.02.006
Keywords
Steatosis; Alcoholic steatohepatitis; Ballooning degeneration; Cholestasis; Sinusoidal fibrosis; Cirrhosis
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The term alcoholic liver disease encompasses a spectrum of pathologic conditions ranging from isolated steatosis to established cirrhosis. Within this spectrum, varying degrees of inflammation, hepatocellular ballooning degeneration, hepatocyte necrosis, cholestasis, and fibrosis may be encountered. This article reviews the characteristic histologic features of the many forms of alcoholic liver disease. Histologic scoring systems are described, and diseases with overlapping morphologic features and comorbid conditions are also discussed.
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