4.8 Article

Looking backward in time to define the chronology of metastasis

Journal

NATURE COMMUNICATIONS
Volume 11, Issue 1, Pages -

Publisher

NATURE PORTFOLIO
DOI: 10.1038/s41467-020-16995-y

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Funding

  1. National Institutes of Health through the NIH Director's Pioneer Award [DP1-CA238296]

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The timing of cancer metastasis has implications for treatment and prevention. Traditional forward-time views of metastasis assume it occurs late during evolution. However, looking backward in time reveals metastasis often occurs prior to clinical detection of primary tumors.

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