Related references
Note: Only part of the references are listed.G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules
Peiguo Yang et al.
CELL (2020)
Norovirus infection results in eIF2α independent host translation shut-off and remodels the G3BP1 interactome evading stress granule formation
Michele Brocard et al.
PLOS PATHOGENS (2020)
Translational Control in Virus-Infected Cells
Noam Stern-Ginossar et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2019)
Upregulation of CHOP participates in caspase activation and virus release in human astrovirus-infected cells
Tomoyasu Isobe et al.
JOURNAL OF GENERAL VIROLOGY (2019)
Essential Role of Enterovirus 2A Protease in Counteracting Stress Granule Formation and the Induction of Type I Interferon
Linda J. Visser et al.
JOURNAL OF VIROLOGY (2019)
HIV-1 requires Staufen1 to dissociate stress granules and to produce infectious viral particles
Shringar Rao et al.
RNA (2019)
Activation of protein kinase R by hepatitis C virus RNA-dependent RNA polymerase
Ryosuke Suzuki et al.
VIROLOGY (2019)
HRI of Epinephelus coioides is a critical factor in the grouper immune response to RGNNV infection
Shaoqing Zang et al.
FISH & SHELLFISH IMMUNOLOGY (2019)
Zika Virus Subverts Stress Granules To Promote and Restrict Viral Gene Expression
Gaston Bonenfant et al.
JOURNAL OF VIROLOGY (2019)
Enhanced Replication of Mouse Adenovirus Type 1 following Virus-Induced Degradation of Protein Kinase R (PKR)
Danielle E. Goodman et al.
MBIO (2019)
Stress Granules and Processing Bodies in Translational Control
Pavel Ivanov et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2019)
Mouse Norovirus Infection Arrests Host Cell Translation Uncoupled from the Stress Granule-PKR-eIF2α Axis
Svenja Fritzlar et al.
MBIO (2019)
The mammalian host protein DAP5 facilitates the initial round of translation of Coxsackievirus B3 RNA
Pratik Dave et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Porcine Circovirus Type 2 Induces ORF3-Independent Mitochondrial Apoptosis via PERK Activation and Elevation of Cytosolic Calcium
Yikai Zhang et al.
JOURNAL OF VIROLOGY (2019)
A viral RNA motif involved in signaling the initiation of translation on non-AUG codons
Miguel Angel Sanz et al.
RNA (2019)
SG formation relies on eIF4GI-G3BP interaction which is targeted by picornavirus stress antagonists
Xiaodan Yang et al.
CELL DISCOVERY (2019)
Evaluation of the Antiviral Activity of Sephin1 Treatment and Its Consequences on eIF2α Phosphorylation in Response to Viral Infections
Maxime Fusade-Boyer et al.
FRONTIERS IN IMMUNOLOGY (2019)
HIV-1 NC-induced stress granule assembly and translation arrest are inhibited by the dsRNA binding protein Staufen1
Shringar Rao et al.
RNA (2018)
The eIF2α Kinase Heme-Regulated Inhibitor Protects the Host from Infection by Regulating Intracellular Pathogen Trafficking
Wael Bahnan et al.
INFECTION AND IMMUNITY (2018)
Curcumin mitigates axonal injury and neuronal cell apoptosis through the PERK/Nrf2 signaling pathway following diffuse axonal injury
Tingqin Huang et al.
NEUROREPORT (2018)
Newcastle disease virus induces G0/G1 cell cycle arrest in asynchronously growing cells
Yan Wang et al.
VIROLOGY (2018)
Enterovirus 71 inhibits cytoplasmic stress granule formation during the late stage of infection
Yating Zhang et al.
VIRUS RESEARCH (2018)
Dengue virus-induced ER stress is required for autophagy activation, viral replication, and pathogenesis both &ITin vitro &ITand &ITin vivo&IT
Ying-Ray Lee et al.
SCIENTIFIC REPORTS (2018)
Picornavirus 2A protease regulates stress granule formation to facilitate viral translation
Xiaodan Yang et al.
PLOS PATHOGENS (2018)
Alphavirus-induced hyperactivation of PI3K/AKT directs pro-viral metabolic changes
Michela Mazzon et al.
PLOS PATHOGENS (2018)
Endoplasmic Reticulum Stress Mediated MDRV p10.8 Protein-Induced Cell Cycle Arrest and Apoptosis Through the PERK/eIF2α Pathway
Quanxi Wang et al.
FRONTIERS IN MICROBIOLOGY (2018)
The Initiation Factors eIF2, eIF2A, eIF2D, eIF4A, and eIF4G Are Not Involved in Translation Driven by Hepatitis C Virus IRES in Human Cells
Esther Gonzalez-Almela et al.
FRONTIERS IN MICROBIOLOGY (2018)
Stress Granule Formation is One of the Early Antiviral Mechanisms for Host Cells Against Coxsackievirus B Infection
Xia Zhai et al.
VIROLOGICA SINICA (2018)
Coxsackievirus A6 Induces Cell Cycle Arrest in G0/G1 Phase for Viral Production
Zengyan Wang et al.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2018)
Porcine reproductive and respiratory syndrome virus inhibits MARC-145 proliferation via inducing apoptosis and G2/M arrest by activation of Chk/Cdc25C and p53/p21 pathway
Linlin Song et al.
VIROLOGY JOURNAL (2018)
HRI coordinates translation by eIF2αP and mTORC1 to mitigate ineffective erythropoiesis in mice during iron deficiency
Shuping Zhang et al.
BLOOD (2018)
PKR induces the expression of NLRP3 by regulating the NF-κB pathway in Porphyromonas gingivalis-infected osteoblasts
Kaya Yoshida et al.
EXPERIMENTAL CELL RESEARCH (2017)
Non-AUG translation: a new start for protein synthesis in eukaryotes
Michael G. Kearse et al.
GENES & DEVELOPMENT (2017)
Inhibition of PKR ameliorates lipopolysaccharide-induced acute lung injury by suppressing NF-κB pathway in mice
Yinjiao Li et al.
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY (2017)
Influenza A Virus Virulence Depends on Two Amino Acids in the N-Terminal Domain of Its NS1 Protein To Facilitate Inhibition of the RNA-Dependent Protein Kinase PKR
Kristina L. Schierhorn et al.
JOURNAL OF VIROLOGY (2017)
Porcine circovirus type 2 capsid protein induces unfolded protein response with subsequent activation of apoptosis
Ying-shan Zhou et al.
JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B (2017)
Decoding the selectivity of eIF2α holophosphatases and PPP1R15A inhibitors
Marta Carrara et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
Prototype foamy virus elicits complete autophagy involving the ER stress-related UPR pathway
Peipei Yuan et al.
RETROVIROLOGY (2017)
Surviving Stress: Modulation of ATF4-Mediated Stress Responses in Normal and Malignant Cells
Inge M. N. Wortel et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2017)
Foot-and-mouth disease virus induces lysosomal degradation of host protein kinase PKR by 3C proteinase to facilitate virus replication
Chuntian Li et al.
VIROLOGY (2017)
Identification of residues within the African swine fever virus DP71L protein required for dephosphorylation of translation initiation factor eIF2α and inhibiting activation of pro-apoptotic CHOP
Claire Barber et al.
VIROLOGY (2017)
Flavivirus Infection Uncouples Translation Suppression from Cellular Stress Responses
Hanna Roth et al.
MBIO (2017)
Decoding the selectivity of eIF2α holophosphatases and PPP1R15A inhibitors
Marta Carrara et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
Hepatitis B virus X protein inhibits apoptosis by modulating endoplasmic reticulum stress response
Jia Li et al.
ONCOTARGET (2017)
Cleavage of poly(A)-binding protein by duck hepatitis A virus 3C protease
Di Sun et al.
SCIENTIFIC REPORTS (2017)
dsRNA Binding Domain of PKR Is Proteolytically Released by Enterovirus A71 to Facilitate Viral Replication
Yu-Hsiu Chang et al.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2017)
Translation of Sindbis Subgenomic mRNA is Independent of eIF2, eIF2A and eIF2D
Miguel Angel Sanz et al.
SCIENTIFIC REPORTS (2017)
A protective role of Heme-regulated eIF2α kinase in cadmium-induced liver and kidney injuries
Lixin Wang et al.
CHEMOSPHERE (2017)
The UPR reduces glucose metabolism via IRE1 signaling
Judith M. van der Harg et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2017)
C/EBPγ Is a Critical Regulator of Cellular Stress Response Networks through Heterodimerization with ATF4
Christopher J. Huggins et al.
MOLECULAR AND CELLULAR BIOLOGY (2016)
Tumor suppressor BTG1 promotes PRMT1-mediated ATF4 function in response to cellular stress
Laurensia Yuniati et al.
ONCOTARGET (2016)
Enterovirus 71 induces anti-viral stress granule-like structures in RD cells
Yuanmei Zhu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)
Regulation of de novo translation of host cells by manipulation of PERK/PKR and GADD34-PP1 activity during Newcastle disease virus infection
Ying Liao et al.
JOURNAL OF GENERAL VIROLOGY (2016)
Principles and Properties of Stress Granules
David S. W. Protter et al.
TRENDS IN CELL BIOLOGY (2016)
Downregulation of protein kinase PKR activation by porcine reproductive and respiratory syndrome virus at its early stage infection
Yueqiang Xiao et al.
VETERINARY MICROBIOLOGY (2016)
PKR Activation Favors Infectious Pancreatic Necrosis Virus Replication in Infected Cells
Amr A. A. Gamil et al.
VIRUSES-BASEL (2016)
Porcine Circovirus 2 Deploys PERK Pathway and GRP78 for Its Enhanced Replication in PK-15 Cells
Yingshan Zhou et al.
VIRUSES-BASEL (2016)
Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress Responses
Huib H. Rabouw et al.
PLOS PATHOGENS (2016)
Translation initiation by the hepatitis C virus IRES requires eIF1A and ribosomal complex remodeling
Zane A. Jaafar et al.
ELIFE (2016)
Endoplasmic reticulum stress-mediated autophagy contributes to bluetongue virus infection via the PERK-eIF2α pathway
Shuang Lv et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
Cap-dependent, scanning-free translation initiation mechanisms
Ora Haimov et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2015)
A Novel Dual Kinase Function of the RET Proto-oncogene Negatively Regulates Activating Transcription Factor 4-mediated Apoptosis
Rozita Bagheri-Yarmand et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Activated PKR inhibits pancreatic β-cell proliferation through sumoylation-dependent stabilization of P53
Ying Song et al.
MOLECULAR IMMUNOLOGY (2015)
An eIF2α-binding motif in protein phosphatase 1 subunit GADD34 and its viral orthologs is required to promote dephosphorylation of eIF2α
Margarito Rojas et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Picornavirus IRES elements: RNA structure and host protein interactions
Encarnacion Martinez-Salas et al.
VIRUS RESEARCH (2015)
A New Laboratory-Based Algorithm to Predict Development of Hepatocellular Carcinoma in Patients With Hepatitis C and Cirrhosis
Hashem B. El-Serag et al.
GASTROENTEROLOGY (2014)
The eIF2α kinases: their structures and functions
Neysan Donnelly et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2013)
Encephalomyocarditis Virus Disrupts Stress Granules, the Critical Platform for Triggering Antiviral Innate Immune Responses
Chen Seng Ng et al.
JOURNAL OF VIROLOGY (2013)
The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression
Wafa B'chir et al.
NUCLEIC ACIDS RESEARCH (2013)
The Host-Encoded Heme Regulated Inhibitor (HRI) Facilitates Virulence-Associated Activities of Bacterial Pathogens
Niraj Shrestha et al.
PLOS ONE (2013)
Selection of autophagy or apoptosis in cells exposed to ER-stress depends on ATF4 expression pattern with or without CHOP expression
Hiroki Matsumoto et al.
BIOLOGY OPEN (2013)
Site-Specific Cleavage of the Host Poly(A) Binding Protein by the Encephalomyocarditis Virus 3C Proteinase Stimulates Viral Replication
Mariko Kobayashi et al.
JOURNAL OF VIROLOGY (2012)
Critical Role of an Antiviral Stress Granule Containing RIG-I and PKR in Viral Detection and Innate Immunity
Koji Onomoto et al.
PLOS ONE (2012)
New Insights into Translational Regulation in the Endoplasmic Reticulum Unfolded Protein Response
Graham D. Pavitt et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)
Autophagy: Renovation of Cells and Tissues
Noboru Mizushima et al.
CELL (2011)
The Leader Protein of Cardioviruses Inhibits Stress Granule Assembly
Fabian Borghese et al.
JOURNAL OF VIROLOGY (2011)
Selective Abrogation of BiP/GRP78 Blunts Activation of NF-κB through the ATF6 Branch of the UPR: Involvement of C/EBPβ and mTOR-Dependent Dephosphorylation of Akt
Shotaro Nakajima et al.
MOLECULAR AND CELLULAR BIOLOGY (2011)
Systematic and Quantitative Assessment of the Ubiquitin-Modified Proteome
Woong Kim et al.
MOLECULAR CELL (2011)
Endoplasmic reticulum stress is induced and modulated by enterovirus 71
Jia-Rong Jheng et al.
CELLULAR MICROBIOLOGY (2010)
Control of Activating Transcription Factor 4 (ATF4) Persistence by Multisite Phosphorylation Impacts Cell Cycle Progression and Neurogenesis
Christopher L. Frank et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
In vivo hepatic endoplasmic reticulum stress in patients with chronic hepatitis C
Tarik Asselah et al.
JOURNAL OF PATHOLOGY (2010)
The African Swine Fever Virus DP71L Protein Recruits the Protein Phosphatase 1 Catalytic Subunit To Dephosphorylate eIF2α and Inhibits CHOP Induction but Is Dispensable for These Activities during Virus Infection
Fuquan Zhang et al.
JOURNAL OF VIROLOGY (2010)
Influenza A Virus Replication Induces Cell Cycle Arrest in G0/G1 Phase
Yuan He et al.
JOURNAL OF VIROLOGY (2010)
Hepatitis C Virus Controls Interferon Production through PKR Activation
Noella Arnaud et al.
PLOS ONE (2010)
Regulation of G(1) Arrest and Apoptosis in Hypoxia by PERK and GCN2-Mediated eIF2 alpha Phosphorylation
Yan Liu et al.
NEOPLASIA (2010)
Stress granules
Paul Anderson et al.
CURRENT BIOLOGY (2009)
Amino acid limitation regulates the expression of genes involved in several specific biological processes through GCN2-dependent and GCN2-independent pathways
Christiane Deval et al.
FEBS JOURNAL (2009)
Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection
Luc English et al.
NATURE IMMUNOLOGY (2009)
HIV-1 Protease Inhibits Cap- and Poly(A)-Dependent Translation upon eIF4GI and PABP Cleavage
Alfredo Castello et al.
PLOS ONE (2009)
The eIF2α kinases inhibit vesicular stomatitis virus replication independently of eIF2α phosphorylation
Jothilatha Krishnamoorthy et al.
CELL CYCLE (2008)
Reprogramming mRNA translation during stress
Satoshi Yamasaki et al.
CURRENT OPINION IN CELL BIOLOGY (2008)
Elucidation of the heme binding site of heme-regulated eukaryotic initiation factor 2α kinase and the role of the regulatory motif in heme sensing by spectroscopic and catalytic studies of mutant proteins
Jotaro Igarashi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Eukaryotic translation initiation machinery can operate in a bacterial-like mode without eIF2
Ilya M. Terenin et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)
Rotavirus infection induces the phosphorylation of eIF2α but prevents the formation of stress granules
Hilda Montero et al.
JOURNAL OF VIROLOGY (2008)
Inhibition of cytoplasmic mRNA stress granule formation by a viral proteinase
James P. White et al.
CELL HOST & MICROBE (2007)
West Nile virus infection activates the unfolded protein response, leading to CHOP induction and apoptosis
Guruprasad R. Medigeshi et al.
JOURNAL OF VIROLOGY (2007)
Activation of PKR: an open and shut case?
James L. Cole
TRENDS IN BIOCHEMICAL SCIENCES (2007)
The PERK/elF2α/ATF4 module of the UPR in hypoxia resistance and tumor growth
Diane R. Fels et al.
CANCER BIOLOGY & THERAPY (2006)
Binding of the influenza A virus NS1 protein to PKR mediates the inhibition of its activation by either PACT or double-stranded RNA
Shoudong Li et al.
VIROLOGY (2006)
Antiviral effect of the mammalian translation initiation factor 2α kinase GCN2 against RNA viruses
Juan J. Berlanga et al.
EMBO JOURNAL (2006)
Hepatitis C virus core triggers apoptosis in liver cells by inducing ER stress and ER calcium depletion
NL Benali-Furet et al.
ONCOGENE (2005)
Autophagy promotes MHC class II presentation of peptides from intracellular source proteins
J Dengjel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Heme-regulated inhibitor kinase-mediated phosphorylation of eukaryotic translation initiation factor 2 inhibits translation, induces stress granule formation, and mediates survival upon arsenite exposure
E McEwen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells
KM Vattem et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival
SB Cullinan et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Delineation of a negative feedback regulatory loop that controls protein translation during endoplasmic reticulum stress
YJ Ma et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Protein synthesis and endoplasmic reticulum stress can be modulated by the hepatitis C virus envelope protein E2 through the eukaryotic initiation factor 2α kinase PERK
N Pavio et al.
JOURNAL OF VIROLOGY (2003)
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress
HP Harding et al.
MOLECULAR CELL (2003)
Growth arrest and DNA damage-inducible protein GADD34 targets protein phosphatase 1α to the endoplasmic reticulum and promotes dephosphorylation of the α subunit of eukaryotic translation initiation factor 2
MH Brush et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response
AH Lee et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Characterization of RNA determinants recognized by the arginine- and proline-rich region of Us11, a herpes simplex virus type 1-encoded double-stranded RNA binding protein that prevents PKR activation
D Khoo et al.
JOURNAL OF VIROLOGY (2002)
Stress granules: sites of mRNA triage that regulate mRNA stability and translatability
N Kedersha et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2002)
Myxoma virus immunomodulatory protein M156R is a structural mimic of eukaryotic translation initiation factor eIF2α
TA Ramelot et al.
JOURNAL OF MOLECULAR BIOLOGY (2002)
The GCN2 eIF2α kinase is required for adaptation to amino acid deprivation in mice
PC Zhang et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Activation of HTLV-1 transcription in the presence of tax is independent of the acetylation of CREB-2 (ATF-4)
F Gachon et al.
VIROLOGY (2002)
ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of golgi localization signals
JS Shen et al.
DEVELOPMENTAL CELL (2002)
The luminal domain of ATF6 senses endoplasmic reticulum (ER) stress and causes translocation of ATF6 from the ER to the Golgi
X Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Gene-specific regulation by general translation factors
TE Dever
CELL (2002)
Regulation of starvation- and virus-induced autophagy by the eIF2α kinase signaling pathway
Z Tallóczy et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2α
I Novoa et al.
JOURNAL OF CELL BIOLOGY (2001)
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs
J Ye et al.
MOLECULAR CELL (2000)
Inhibition of PKR activation by the proline-rich RNA binding domain of the herpes simplex virus type 1 Us11 protein
J Poppers et al.
JOURNAL OF VIROLOGY (2000)
Regulated translation initiation controls stress-induced gene expression in mammalian cells
HP Harding et al.
MOLECULAR CELL (2000)
Phosphorylation of serine 51 in initiation factor 2α (eIF2α) promotes complex formation between eIF2α(P) and eIF2B and causes inhibition in the guanine nucleotide exchange activity of eIF2B
A Sudhakar et al.
BIOCHEMISTRY (2000)
A multifactor complex of eukaryotic initiation factors, eIE1, eIF2, eIF3, eIF5, and initiator tRNAMet is an important translation initiation intermediate in vivo
K Asano et al.
GENES & DEVELOPMENT (2000)
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response
A Bertolotti et al.
NATURE CELL BIOLOGY (2000)
Perk is essential for translational regulation and cell survival during the unfolded protein response
HP Harding et al.
MOLECULAR CELL (2000)
Two heme-binding domains of heme-regulated eukaryotic initiation factor-2α kinase -: N terminus and kinase insertion
M Rafie-Kolpin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)