The effect of diet components on cancer with epigenetic mechanisms

Cancer is the most important cause of mortality worldwide. Nutritional style, smoking habGSits, body weight and some lifestyle factors such as modifiable risk factors are also effective in increasing of disease. It is known that dietary components that have an effect on cancer may affect the carcinogenesis process. It is believed that resveratrol, selenium, isothiocyanates such as sulforafan, curcumin, tea polyphenols, genistein, quercetin, anthocyanins, withaferin A and indole-3-carbinol may prevent and/or be effective in the treatment of various types of cancer by epigenetic mechanisms. These epigenetic mechanisms include DNA methylation, histone modification, and non-coding RNAs. It is hopeful that bioactive dietary components may prevent and/or treat cancer by epigenetic mechanisms, either alone or often in combination with several dietary components. In general, studies supporting the health benefits of epigenetics are increasing and it is thought that nutrients and food components may have an epigenetic effect on cancer with the available information. At the same time, nutrients and bioactive nutrients can slow the progression of cancer. This study was planned and conducted to investigate the effect of cancer on the epigenetic mechanisms of nutrients and their components.