Journal
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
Volume 127, Issue -, Pages -Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.trac.2020.115891
Keywords
Antibiotics; Antimicrobial resistance; Susceptibility testing; Emerging technologies; Bacterial infection diagnostics
Categories
Funding
- European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant [675412]
- ERA-NET Cofund Water Works 2015 Call (this ERA-NET is an integral part of the 2016 Joint Activities developed by the Water Challenges for a Changing World Joint Programme Initiative, Water JPI)
- Ministry of Science, Innovation and Universities Spain (QS4CF) [RTI2018-096278-B-C21]
- Marato TV3 Foundation (QS-Motion) [TV32018-201825-30-31]
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The emergence and spread of bacterial resistances to antibiotics is now leading to the antibiotic crisis. This is driven by the antibiotic misuse and disabuse, rendered possible due to the absence of fast and accurate technologies for antibiotic screening and resistant bacteria identification in infectious diseases. Technologies that provide sensitive, quick and easy read-outs, conveying information about the optimal treatment are required. A multitude of these tests is readily available on the market, with many more being developed. However, current methods have their shortcomings. An in depth study overview and analysis of the field, with a deep focus on the current market, will serve as a guideline for the future emerging technologies involving susceptibility testing and antibiotic resistance evaluation. From such a dynamic and growing field, the current review provides a critical discussion on how the susceptibility-testing field is developing and where it is going. (c) 2020 Elsevier B.V. All rights reserved.
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