Journal
THORAX
Volume 75, Issue 10, Pages 908-912Publisher
BMJ PUBLISHING GROUP
DOI: 10.1136/thoraxjnl-2020-214703
Keywords
lung cancer; imaging; CT MRI etc
Categories
Funding
- National Awareness and Early Diagnosis Initiative (NAEDI) project grant - Cancer Research UK (CRUK)
- Department of Health (England)
- Economic and Social Research Council
- Health and Social Care R&D Division, Public Health Agency, Northern Ireland
- National Institute for Social Care and Health Research, Wales
- Scottish Government
- Wellcome Trust [WT107963AIA]
- Rosetrees Trust
- Roy Castle Lung Cancer Foundation
- Stoneygate Trust
- Welton Trust
- Garfield Weston Trust
- UCLH Charitable Foundation
- Department of Health's NIHR Biomedical Research Centre's funding scheme
- CRUK Postdoctoral Fellowship [C50664/A24460]
- MRC [MR/T02481X/1] Funding Source: UKRI
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The Lung Screen Uptake Trial tested a novel invitation strategy to improve uptake and reduce socioeconomic and smoking-related inequalities in lung cancer screening (LCS) participation. It provides one of the first UK-based 'real-world' LCS cohorts. Of 2012 invited, 1058 (52.6%) attended a 'lung health check'. 768/996 (77.1%) in the present analysis underwent a low-dose CT scan. 92 (11.9%) and 33 (4.3%) participants had indeterminate pulmonary nodules requiring 3-month and 12-month surveillance, respectively; 36 lung cancers (4.7%) were diagnosed (median follow-up: 1044 days). 72.2% of lung cancers were stage I/II and 79.4% of non-small cell lung cancer had curative-intent treatment.
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