4.6 Article

SpyGlass-guided laser lithotripsy versus laparoscopic common bile duct exploration for large common bile duct stones: a non-inferiority trial

Journal

Publisher

SPRINGER
DOI: 10.1007/s00464-020-07862-4

Keywords

Common bile duct stones; Laser lithotripsy; Laparoscopy; Common bile duct exploration

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Funding

  1. Jinan healthcare science and technology plan [201602174]

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The clinical efficacy and safety of SpyGlass-guided laser lithotripsy LCBDE for large CBD stones are comparable to traditional LCBDE, but with less invasiveness. Patients in Group A had shorter hospital stays and enhanced recovery compared to Group B.
Background Laparoscopic common bile duct exploration (LCBDE) is the first choice of treatment for large common bile duct (CBD) stones. Recently, single-operator cholangioscopy (SpyGlass system) has been introduced widely in referral and large medical centers. Several studies have reported favorable results for treatment of large CBD stones guided by SpyGlass. We evaluated the clinical efficacy and safety of SpyGlass-guided laser lithotripsy LCBDE for treatment of large CBD stones. Methods From August 2015 to August 2018, 157 patients with large bile duct stones who met the inclusion criteria were randomly divided into two groups: SpyGlass-guided laser lithotripsy (Group A) and LCBDE (Group B). The efficacy and complications were compared between the groups. Results Although the first-session stone removal rate in Group A was significantly lower than that in Group B, Group A was not inferior to Group B in terms of total stone removal rate. Compared with Group B, Group A had shorter hospital stay and enhanced recovery. The short-term complication rates were also similar between the two groups. Conclusions The clinical efficacy of SpyGlass-guided laser lithotripsy for the treatment of large CBD stones is not inferior to that of LCBDE, and it is less invasive. SpyGlass-guided laser lithotripsy is an important option for treatment of large CBD stones.

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