Journal
CLINICAL PHARMACOLOGY & THERAPEUTICS
Volume 101, Issue 1, Pages 24-27Publisher
WILEY
DOI: 10.1002/cpt.528
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Funding
- International Society of Pharmacometrics QSP Special Interest Group
- ASCPT Systems Pharmacology Community
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Quantitative systems pharmacology (QSP) has emerged as an innovative approach in model-informed drug discovery and development, supporting program decisions from exploratory research through late-stage clinical trials. In this commentary, we discuss the unique value of disease-scale platform QSP models that are amenable to reuse and repurposing to support diverse clinical decisions in ways distinct from other pharmacometrics strategies.
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