Journal
CLINICAL PHARMACOLOGY & THERAPEUTICS
Volume 100, Issue 1, Pages 53-62Publisher
WILEY
DOI: 10.1002/cpt.382
Keywords
-
Categories
Ask authors/readers for more resources
The pharmacokinetics of many drugs are altered by pregnancy. Drug distribution and protein binding are changed by pregnancy. While some drug metabolizing enzymes have an apparent increase in activity, others have an apparent decrease in activity. Not only is drug metabolism affected by pregnancy, but renal filtration is also increased. In addition, pregnancy alters the apparent activities of multiple drug transporters resulting in changes in the net renal secretion of drugs.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available