Journal
SENSORS
Volume 20, Issue 14, Pages -Publisher
MDPI
DOI: 10.3390/s20144022
Keywords
breast cancer; nanobiosensors; biomarkers; electrochemistry; impedance; immobilization; nanomaterial; nanoparticles (NPs); magnetic NPs; self-assembled monolayers (SAMs); signal amplification
Funding
- Slovak Research and Development Agency [APVV 17-0300]
- Qatar University [IRCC-2020-004]
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This comprehensive review paper describes recent advances made in the field of electrochemical nanobiosensors for the detection of breast cancer (BC) biomarkers such as specific genes, microRNA, proteins, circulating tumor cells, BC cell lines, and exosomes or exosome-derived biomarkers. Besides the description of key functional characteristics of electrochemical nanobiosensors, the reader can find basic statistic information about BC incidence and mortality, breast pathology, and current clinically used BC biomarkers. The final part of the review is focused on challenges that need to be addressed in order to apply electrochemical nanobiosensors in a clinical practice.
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