4.4 Article

Validation of the Musculoskeletal Health Questionnaire (MSK-HQ) in primary care patients with musculoskeletal pain

Journal

SEMINARS IN ARTHRITIS AND RHEUMATISM
Volume 50, Issue 5, Pages 813-820

Publisher

W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.semarthrit.2020.06.022

Keywords

Musculoskeletal; Patient reported outcome measures; Primary care; Quality of life

Categories

Funding

  1. National Institute for Health Research (NIHR) under its Programme Grants for Applied Research (PGfAR) Programme [RP-PG-1211-20010]
  2. NIHR Research Professorship [NIHR-RP-011-015]
  3. NIHR West Midlands Clinical Research Network (Clinical Trials Scholarship)
  4. Versus Arthritis [20202]
  5. Department of Health and Social Care

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Objective: To evaluate the responsiveness, and concurrent validity of the Musculoskeletal Health Questionnaire (MSK-HQ) in UK primary care patients with common musculoskeletal (MSK) pain presentations. Methods: A secondary analysis of a primary care pilot randomised trial (STarT MSK) was performed. In 524 people consulting with back, neck, shoulder, knee, or multi-site pain, the following were recorded at 0/6 months: MSK-HQ EQ-5D-5L, Roland-Morris Disability Questionnaire (RMDQ; back pain), Neck Disability Index (NDI), Shoulder Pain and Disability Index (SPADI), Knee Injury and Outcome Score (KOOS), ShortForm-12 (SF-12; multisite pain). At 6 -months, patients self-rated their global change in MSK condition, from -5 (very much worse) to +5 (completely recovered). Receiver operating characteristic curves evaluated abilities of 6-month changes in each patient reported outcome measure (PROM) to discriminate between patients improving/not improving on global change scores, with Minimal Clinically Important Differences (MCID) calculated. Results: The MSK-HQ had a good ability to discriminate between MSK pain patients reporting global improvement vs. no improvement (area under the curve [AUC] 0.81; 95% CI 0.78, 0.85). Its discriminative ability was higher than the EQ-5D-5L (AUC 0.68; 95% CI 0.62, 0.73) and similar to site -specific PROMs. The MCID for the 6-month change in MSK-HQ was 5.5. The MSK-HQ had strong correlations with all PROMs, except SF-12 scores. Conclusion: In primary care patients with common MSK pain presentations, the MSK-HQ was as good as existing pain-site specific PROMs at identifying people reporting global improvements in their MSK condition, and was better than the EQ-5D-5L. (C) 2020 Elsevier Inc. All rights reserved.

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