4.5 Editorial Material

Bacterial invaders drive CRC progression

Journal

SCIENCE SIGNALING
Volume 13, Issue 644, Pages -

Publisher

AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/scisignal.abc4218

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Funding

  1. National Cancer Institute (U.S.A.)
  2. Cancer Research UK Grand Challenge program
  3. Janssen
  4. Novo Ventures
  5. Ono
  6. Bayer

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The oral bacterium Fusobacterium nucleatum is often found in colorectal cancer (CRC). In the 21 July 2020 issue of Science Signaling, Casasanta et al. show that CRC cell-resident F. nucleatum promotes cytokine secretion that may potentiate tumor growth and metastatic progression in patients.

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