4.1 Article

Effects of eight weeks of moderate intensity aerobic training and training in water on DNA damage, lipid peroxidation and total antioxidant capacity in sixty years sedentary women

Journal

SCIENCE & SPORTS
Volume 36, Issue 3, Pages E81-E85

Publisher

ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.scispo.2020.04.005

Keywords

Aerobic training; DNA oxidative damage; 8-isoprostane; Elderly women

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The study aimed to investigate the effects of eight weeks of aerobic and water training on oxidative stress indices and total antioxidant capacity in elderly women. The results showed that moderate aerobic exercise can reduce oxidative stress-induced damage and increase antioxidant system capacity.
Objectives. - The aim of this study was to investigate the effect of eight weeks of aerobic training and training in water on oxidative stress indices and total antioxidant capacity in elderly women. Equipment and methods. - A total of 45 volunteered women participate as a subject for the study. Subjects were randomly divided into three groups; Aerobic (15 subjects), Training in water (15 subjects) and Control (15 subjects). Before the beginning of the training period, 8-OHdG, 8-isoprostane and total antioxidant capacity were measured. Both training groups were performed aerobic exercise on lane and water for three sessions per week with 65-75 percent of maximum heart rate. At the end of the training period, again, the blood sampling was repeated. For the statically analysis, ANOVA test was used, and for significant variables Bunferroni post hoc was used. Results. - Results showed significant difference in the level of OHdG, 8-isoprostane and total antioxidant capacity between trained groups and the control group after the training period (P < 0.004, P < 0.002, respectively). There was no significant difference between training groups in all variables (P < 0.734). In general, the results showed that moderate aerobic exercise in water and land can decrease oxidative stress induced damage and increase antioxidant system capacity. (C) 2020 Elsevier Masson SAS. All rights reserved.

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