Electrochemical sensors and biosensors on the pillar[5]arene platform

The key options for the synthesis of functionalized pillar[5]arenes and their applications in electrochemical sensors and biosensors are considered. Examples of using the macrocycle as an electron transfer mediator, a reactant for the formation of host-guest complexes, and a carrier of biochemical receptors are given. Details of behavior and ways of inclusion of pillararenes into the surface layer of electrochemical sensors are indicated. The trends of further development of pillararene chemistry are discussed as applied to the problems of advancement of electrochemical sensors.