Long-term outcomes of simultaneous guided bone regeneration using native and cross-linked collagen membranes after 8years

ObjectivesTo assess the clinical outcomes of simultaneous guided bone regeneration using native (CM) and cross-linked (VN) collagen membranes at 8years. Materials and methodsA total of n=19 patients (19 implants) were available for the analysis. Each subject had received a simultaneous grafting of dehiscence-type defects using a natural bone mineral (NBM) and a random allocation to either CM and VN membranes (submerged healing of 4months). Clinical parameters (e.g., bleeding on probing - BOP, probing pocket depth - PD, mucosal recession - MR, clinical attachment level - CAL) were recorded at 8years after prosthesis installation. ResultsAt 8years, CM and VN groups revealed comparable median BOP, PD, MR and CAL values at both vestibular and oral aspects. From 4 to 8years (n=14 patients), median CAL at the vestibular aspect improved in both groups; however, these changes were significantly higher at CM-treated sites (CM: 0.7mm vs. VN: 0.5mm). ConclusionThe clinical long-term outcomes at 8years were comparable in both VN and CM groups.