Journal
PATHOLOGE
Volume 41, Issue 5, Pages 471-477Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s00292-020-00802-y
Keywords
Hepatic sinusoidal obstruction syndrome; Peliosis hepatis; Hepatic endothelial neoplasias; Hepatomegaly; Hepatic vascular remodeling
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This review covers a spectrum of pathologic changes and diseases involving hepatic sinusoids. In the majority of patients, clinical findings are rather uncharacteristic such as hepatomegaly, portal hypertension, or lingering liver failure of unknown origin. In contrast to more common hepatic disorders, characteristic clinical, serological, immunoserological, and radiographical findings are lacking. In these cases, biopsy findings may be crucial to guide treatment decisions. This review covers a variety of hepatic disorders that practicing pathologists may encounter in their clinical routine.
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