Journal
ORGANIC LETTERS
Volume 22, Issue 15, Pages 6031-6034Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.0c02125
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Funding
- National Natural Science Foundation of China [21925111, 21790333, 21672199, 21702197]
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A Bronsted acid catalyzed cyclization of aminodiazoesters with aldehydes is described. This reaction features broad substrate generality and functional group compatibility, affording a wide range of 5-7-membered 3-carboxylate-N-heterocycles containing different functional groups. The title products are able to be further elaborated through simple functional group transformations to produce synthetically useful N-heterocycles.
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