Related references
Note: Only part of the references are listed.Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy
Kevin B. Einkauf et al.
JOURNAL OF CLINICAL INVESTIGATION (2019)
Cat and Mouse: HIV Transcription in Latency, Immune Evasion and Cure/Remission Strategies
Aurelie Delannoy et al.
VIRUSES-BASEL (2019)
Impact of LEDGIN treatment during virus production on residual HIV-1 transcription
Gerlinde Vansant et al.
RETROVIROLOGY (2019)
HIV shock and kill therapy: In need of revision
Erik Abner et al.
ANTIVIRAL RESEARCH (2019)
Nuclear pores in genome architecture and enhancer function
Pau Pascual-Garcia et al.
CURRENT OPINION IN CELL BIOLOGY (2019)
Toward understanding the origin and evolution of cellular organisms
Minoru Kanehisa
PROTEIN SCIENCE (2019)
New approach for understanding genome variations in KEGG
Minoru Kanehisa et al.
NUCLEIC ACIDS RESEARCH (2019)
Insight in HIV Integration Site Selection Provides a Block-and-Lock Strategy for a Functional Cure of HIV Infection
Zeger Debyser et al.
VIRUSES-BASEL (2019)
Getting the Kill into Shock and Kill: Strategies to Eliminate Latent HIV
Youry Kim et al.
CELL HOST & MICROBE (2018)
Proviruses with Long-Term Stable Expression Accumulate in Transcriptionally Active Chromatin Close to the Gene Regulatory Elements: Comparison of ASLV-, HIV- and MLV-Derived Vectors
Dalibor Miklik et al.
VIRUSES-BASEL (2018)
Distinct chromatin functional states correlate with HIV latency reactivation in infected primary CD4+ T cells
Emilie Battivelli et al.
ELIFE (2018)
Capsid-CPSF6 Interaction Licenses Nuclear HIV-1 Trafficking to Sites of Viral DNA Integration
Vasudevan Achuthan et al.
CELL HOST & MICROBE (2018)
Nuclear landscape of HIV-1 infection and integration
Marina Lusic et al.
NATURE REVIEWS MICROBIOLOGY (2017)
Position effects influence HIV latency reversal
Heng-Chang Chen et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
Position effects influence HIV latency reversal
Heng-Chang Chen et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
Metazoan Nuclear Pores Provide a Scaffold for Poised Genes and Mediate Induced Enhancer-Promoter Contacts
Pau Pascual-Garcia et al.
MOLECULAR CELL (2017)
Modulation of the functional association between the HIV-1 intasome and the nucleosome by histone amino-terminal tails
Mohamed S. Benleulmi et al.
RETROVIROLOGY (2017)
HIV Latency: Should We Shock or Lock?
Gilles Darcis et al.
TRENDS IN IMMUNOLOGY (2017)
Multiple Histone Lysine Methyltransferases Are Required for the Establishment and Maintenance of HIV-1 Latency
Kien Nguyen et al.
MBIO (2017)
In Vivo Suppression of HIV Rebound by Didehydro-Cortistatin A, a Block-and-Lock'' Strategy for HIV-1 Treatment
Cari F. Kessing et al.
CELL REPORTS (2017)
On the way to find a cure: Purging latent HIV-1 reservoirs
Christian Schwartz et al.
BIOCHEMICAL PHARMACOLOGY (2017)
In Situ Capture of Chromatin Interactions by Biotinylated dCas9
Xin Liu et al.
CELL (2017)
Zerone: a ChIP-seq discretizer for multiple replicates with built-in quality control
Pol Cusco et al.
BIOINFORMATICS (2016)
Retroviral DNA Integration
Paul Lesbats et al.
CHEMICAL REVIEWS (2016)
Nucleoporin-mediated regulation of cell identity genes
Arkaitz Ibarra et al.
GENES & DEVELOPMENT (2016)
The Cleavage and Polyadenylation Specificity Factor 6 (CPSF6) Subunit of the Capsid-recruited Pre-messenger RNA Cleavage Factor I (CFIm) Complex Mediates HIV-1 Integration into Genes
Sheeba Rasheedi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
The many faces of histone H3K79 methylation
Zeenat Farooq et al.
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2016)
Near-optimal probabilistic RNA-seq quantification
Nicolas L. Bray et al.
NATURE BIOTECHNOLOGY (2016)
International AIDS Society global scientific strategy: towards an HIV cure 2016
Steven G. Deeks et al.
NATURE MEDICINE (2016)
A critical role for alternative polyadenylation factor CPSF6 in targeting HIV-1 integration to transcriptionally active chromatin
Gregory A. Sowd et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Development of 5′ LTR DNA methylation of latent HIV-1 provirus in cell line models and in long-term-infected individuals
Katerina Trejbalova et al.
CLINICAL EPIGENETICS (2016)
LEDGIN-mediated Inhibition of Integrase-LEDGF/p75 Interaction Reduces Reactivation of Residual Latent HIV
Lenard S. Vranckx et al.
EBIOMEDICINE (2016)
Retroviral integration: Site matters: Mechanisms and consequences of retroviral integration site selection
Jonas Demeulemeester et al.
BIOESSAYS (2015)
Impact of Nucleoporin-Mediated Chromatin Localization and Nuclear Architecture on HIV Integration Site Selection
Richard W. Wong et al.
JOURNAL OF VIROLOGY (2015)
Nuclear architecture dictates HIV-1 integration site selection
Bruna Marini et al.
NATURE (2015)
What are super-enhancers?
Sebastian Pott et al.
NATURE GENETICS (2015)
The Tat Inhibitor Didehydro-Cortistatin A Prevents HIV-1 Reactivation from Latency
Guillaume Mousseau et al.
MBIO (2015)
Chromatin organization at the nuclear pore favours HIV replication
Mickael Lelek et al.
NATURE COMMUNICATIONS (2015)
Direct Visualization of HIV-1 Replication Intermediates Shows that Capsid and CPSF6 Modulate HIV-1 Intra-nuclear Invasion and Integration
Christopher R. Chin et al.
CELL REPORTS (2015)
HIV Tat controls RNA Polymerase II and the epigenetic landscape to transcriptionally reprogram target immune cells
Jonathan E. Reeder et al.
ELIFE (2015)
Epigenetic Heterogeneity in HIV-1 Latency Establishment
Yuka Matsuda et al.
SCIENTIFIC REPORTS (2015)
LEDGINs, non-catalytic site inhibitors of HIV-1 integrase: a patent review (2006-2014)
Jonas Demeulemeester et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2014)
New ex vivo approaches distinguish effective and ineffective single agents for reversing HIV-1 latency in vivo
C. Korin Bullen et al.
NATURE MEDICINE (2014)
Structural basis of HIV-1 capsid recognition by PF74 and CPSF6
Akash Bhattacharya et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element
Marc R. Mansour et al.
SCIENCE (2014)
Quantitative ChIP-Seq Normalization Reveals Global Modulation of the Epigenome
David A. Orlando et al.
CELL REPORTS (2014)
Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure
Ya-Chi Ho et al.
CELL (2013)
Structural basis for high-affinity binding of LEDGF PWWP to mononucleosomes
Jocelyn O. Eidahl et al.
NUCLEIC ACIDS RESEARCH (2013)
Non-Catalytic Site HIV-1 Integrase Inhibitors Disrupt Core Maturation and Induce a Reverse Transcription Block in Target Cells
Mini Balakrishnan et al.
PLOS ONE (2013)
Allosteric integrase inhibitor potency is determined through the inhibition of HIV-1 particle maturation
Kellie A. Jurado et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Nuclear import of APOBEC3F-labeled HIV-1 preintegration complexes
Ryan C. Burdick et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Single-Cell Imaging of HIV-1 Provirus (SCIP)
Cristina Di Primio et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
LEDGINs inhibit late stage HIV-1 replication by modulating integrase multimerization in the virions
Belete Ayele Desimmie et al.
RETROVIROLOGY (2013)
Dual inhibition of HIV-1 replication by integrase-LEDGF allosteric inhibitors is predominant at the post-integration stage
Erwann Le Rouzic et al.
RETROVIROLOGY (2013)
Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication
Francesca Di Nunzio et al.
VIROLOGY (2013)
Nucleosomal DNA binding drives the recognition of H3K36-methylated nucleosomes by the PSIP1-PWWP domain
Rick van Nuland et al.
EPIGENETICS & CHROMATIN (2013)
Nucleoporin NUP153 Phenylalanine-Glycine Motifs Engage a Common Binding Pocket within the HIV-1 Capsid Protein to Mediate Lentiviral Infectivity
Kenneth A. Matreyek et al.
PLOS PATHOGENS (2013)
Small-Molecule Inhibitors of the LEDGF/p75 Binding Site of Integrase Block HIV Replication and Modulate Integrase Multimerization
Frauke Christ et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2012)
New Class of HIV-1 Integrase (IN) Inhibitors with a Dual Mode of Action
Manuel Tsiang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Multimode, Cooperative Mechanism of Action of Allosteric HIV-1 Integrase Inhibitors
Jacques J. Kessl et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters
Guangchuang Yu et al.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY (2012)
HRP-2 determines HIV-1 integration site selection in LEDGF/p75 depleted cells
Rik Schrijvers et al.
RETROVIROLOGY (2012)
Psip1/Ledgf p52 Binds Methylated Histone H3K36 and Splicing Factors and Contributes to the Regulation of Alternative Splicing
Madapura M. Pradeepa et al.
PLOS GENETICS (2012)
LEDGF/p75-Independent HIV-1 Replication Demonstrates a Role for HRP-2 and Remains Sensitive to Inhibition by LEDGINs
Rik Schrijvers et al.
PLOS PATHOGENS (2012)
CPSF6 Defines a Conserved Capsid Interface that Modulates HIV-1 Replication
Amanda J. Price et al.
PLOS PATHOGENS (2012)
Allosteric Inhibitor Development Targeting HIV-1 Integrase
Laith Q. Al-Mawsawi et al.
CHEMMEDCHEM (2011)
Epigenetic signatures distinguish multiple classes of enhancers with distinct cellular functions
Gabriel E. Zentner et al.
GENOME RESEARCH (2011)
Influence of Host Gene Transcription Level and Orientation on HIV-1 Latency in a Primary-Cell Model
Liang Shan et al.
JOURNAL OF VIROLOGY (2011)
Chromatin Reassembly Factors Are Involved in Transcriptional Interference Promoting HIV Latency
Edurne Gallastegui et al.
JOURNAL OF VIROLOGY (2011)
Structural and Histone Binding Ability Characterizations of Human PWWP Domains
Hong Wu et al.
PLOS ONE (2011)
HIV Integration Targeting: A Pathway Involving Transportin-3 and the Nuclear Pore Protein RanBP2
Karen E. Ocwieja et al.
PLOS PATHOGENS (2011)
Flexible Use of Nuclear Import Pathways by HIV-1
KyeongEun Lee et al.
CELL HOST & MICROBE (2010)
Establishment of HIV Latency in Primary CD4+ Cells Is due to Epigenetic Transcriptional Silencing and P-TEFb Restriction
Mudit Tyagi et al.
JOURNAL OF VIROLOGY (2010)
Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication
Frauke Christ et al.
NATURE CHEMICAL BIOLOGY (2010)
Reciprocal intronic and exonic histone modification regions in humans
Jason T. Huff et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
Histone H3K27ac separates active from poised enhancers and predicts developmental state
Menno P. Creyghton et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
HIV integration site distributions in resting and activated CD4+ T cells infected in culture
Troy Brady et al.
AIDS (2009)
HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation
Nicolas Chomont et al.
NATURE MEDICINE (2009)
DNA Specificity Determinants Associate with Distinct Transcription Factor Functions
Peter C. Hollenhorst et al.
PLOS GENETICS (2009)
CpG Methylation Controls Reactivation of HIV from Latency
Jana Blazkova et al.
PLOS PATHOGENS (2009)
Orientation-dependent regulation of integrated HIV-1 expression by host gene transcriptional readthrough
Yefei Han et al.
CELL HOST & MICROBE (2008)
A glimpse into the epigenetic landscape of gene regulation
Jane Mellor et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2008)
Epigenetic Silencing of Human Immunodeficiency Virus (HIV) Transcription by Formation of Restrictive Chromatin Structures at the Viral Long Terminal Repeat Drives the Progressive Entry of HIV into Latency
Richard Pearson et al.
JOURNAL OF VIROLOGY (2008)
Combinatorial patterns of histone acetylations and methylations in the human genome
Zhibin Wang et al.
NATURE GENETICS (2008)
HIV-1 Pre-Integration Complexes Selectively Target Decondensed Chromatin in the Nuclear Periphery
Alberto Albanese et al.
PLOS ONE (2008)
HIV integration site selection: Analysis by massively parallel pyrosequencing reveals association with epigenetic modifications
Gary P. Wang et al.
GENOME RESEARCH (2007)
LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration
Ming-Chieh Shun et al.
GENES & DEVELOPMENT (2007)
Selection of target sites for mobile DNA integration in the human genome
Charles Berry et al.
PLOS COMPUTATIONAL BIOLOGY (2006)
A role for LEDGF/p75 in targeting HIV DNA integration
A Ciuffi et al.
NATURE MEDICINE (2005)
Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75
P Cherepanov et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Genome-wide analysis of chromosomal features repressing human immunodeficiency virus transcription
MK Lewinski et al.
JOURNAL OF VIROLOGY (2005)
Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75
P Cherepanov et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2005)
Spatial distribution of di- and tri-methyl lysine 36 of histone H3 at active genes
AJ Bannister et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Symmetrical base preferences surrounding HIV-1 and avian sarcoma/leukosis virus but not murine leukemia virus integration sites
AG Holman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Weak palindromic consensus sequences are a common feature found at the integration target sites of many retroviruses
XL Wu et al.
JOURNAL OF VIROLOGY (2005)
HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells
P Cherepanov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
HIV-1 integration in the human genome favors active genes and local hotspots
ARW Schröder et al.
CELL (2002)
The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation
A Jordan et al.
EMBO JOURNAL (2001)
KEGG: Kyoto Encyclopedia of Genes and Genomes
M Kanehisa et al.
NUCLEIC ACIDS RESEARCH (2000)
Share Paper
