Journal
NEUROLOGICAL SCIENCES
Volume 41, Issue 12, Pages 3503-3515Publisher
SPRINGER-VERLAG ITALIA SRL
DOI: 10.1007/s10072-020-04527-x
Keywords
Event-related potentials; Olfactory-evoked potentials; TMS-EEG; Event-related fields; Magnetoencephalography; Limits; Reliability; Clinical application
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This review focuses on new and/or less standardized event-related potentials methods, in order to improve their knowledge for future clinical applications. The olfactory event-related potentials (OERPs) assess the olfactory functions in time domain, with potential utility in anosmia and degenerative diseases. The transcranial magnetic stimulation-electroencephalography (TMS-EEG) could support the investigation of the intracerebral connections with very high temporal discrimination. Its application in the diagnosis of disorders of consciousness has achieved recent confirmation. Magnetoencephalography (MEG) and event-related fields (ERF) could improve spatial accuracy of scalp signals, with potential large application in pre-surgical study of epileptic patients. Although these techniques have methodological limits, such as high inter- and intraindividual variability and high costs, their diffusion among researchers and clinicians is hopeful, pending their standardization.
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