4.7 Article

Plague as a cause for familial Mediterranean fever

Journal

NATURE IMMUNOLOGY
Volume 21, Issue 8, Pages 833-834

Publisher

NATURE PORTFOLIO
DOI: 10.1038/s41590-020-0724-3

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Funding

  1. Institut Pasteur
  2. CNRS
  3. French Government's Investissement d'Avenir program project
  4. French Government's Laboratoires d'Excellence Integrative Biology of Emerging Infectious Diseases project [ANR-10-LABX-62-IBEID]
  5. French Government's Milieu Interieur project [ANR-10-LABX-69-01]
  6. Fondation pour la Recherche Medicale [Equipe FRM DEQ20180339214]
  7. Agence Nationale de la Recherche grant 'MORTUI' [ANR-19-CE35-0005-01]
  8. Agence Nationale de la Recherche (ANR) [ANR-19-CE35-0005] Funding Source: Agence Nationale de la Recherche (ANR)

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Evolutionary genetic and experimental analyses suggest that mutations causing familial Mediterranean fever have been positively selected in the Middle East, probably because they confer heightened resistance againstYersinia pestisinfection.

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