Journal
NATURE CHEMICAL BIOLOGY
Volume 16, Issue 11, Pages 1157-1158Publisher
NATURE RESEARCH
DOI: 10.1038/s41589-020-0620-z
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Two recent studies identified CDK12 inhibitors that bind to CDK12-cyclin K complexes and act as molecular glues to stabilize an interaction with the ubiquitin ligase CUL4-DDB1, leading to cyclin K degradation.
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