Related references
Note: Only part of the references are listed.Functional Screening of Candidate Causal Genes for Insulin Resistance in Human Preadipocytes and Adipocytes
Zhifen Chen et al.
CIRCULATION RESEARCH (2020)
Isothermal Analysis of ThermoFluor Data can readily provide Quantitative Binding Affinities
Nan Bai et al.
SCIENTIFIC REPORTS (2019)
Gene-by-Sex Interactions in Mitochondria! Functions and Cardio-Metabolic Traits
Frode Norheim et al.
CELL METABOLISM (2019)
Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes
Angli Xue et al.
NATURE COMMUNICATIONS (2018)
Genetics of blood lipids among ∼300,000 multi-ethnic participants of the Million Veteran Program
Derek Klarin et al.
NATURE GENETICS (2018)
CHARMM36m: an improved force field for folded and intrinsically disordered proteins
Jing Huang et al.
NATURE METHODS (2017)
Small molecules as activators in medicinal chemistry (2000-2016)
Abdul Hameed et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2017)
Genome-wide physical activity interactions in adiposity. A meta-analysis of 200,452 adults
Mariaelisa Graff et al.
PLOS GENETICS (2017)
Lyplal1 is dispensable for normal fat deposition in mice
Rachel A. Watson et al.
DISEASE MODELS & MECHANISMS (2017)
Discovery of a Selective Covalent Inhibitor of Lysophospholipase-like 1 (LYPLAL1) as a Tool to Evaluate the Role of this Serine Hydrolase in Metabolism
Kay Ahn et al.
ACS CHEMICAL BIOLOGY (2016)
Molecular Mechanism for Isoform-Selective Inhibition of Acyl Protein Thioesterases 1 and 2 (APT1 and APT2)
Sang Joon Won et al.
ACS CHEMICAL BIOLOGY (2016)
Moving Beyond Active-Site Detection: MixMD Applied to Allosteric Systems
Phani Ghanakota et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2016)
Activity-Based Protein Profiling: Recent Advances in Probe Development and Applications
Pengyu Yang et al.
CHEMBIOCHEM (2015)
Obesity associated Lyplal1 gene is regulated in diet induced obesity but not required for adipocyte differentiation
Xinnuo Lei et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2015)
New genetic loci link adipose and insulin biology to body fat distribution
Dmitry Shungin et al.
NATURE (2015)
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study
Thomas W. Winkler et al.
PLOS GENETICS (2015)
The Use of Chlorobenzene as a Probe Molecule in Molecular Dynamics Simulations
Yaw Sing Tan et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2014)
integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes
Eduardo Dominguez et al.
NATURE CHEMICAL BIOLOGY (2014)
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
Sonja I. Berndt et al.
NATURE GENETICS (2013)
Automation of the CHARMM General Force Field (CGenFF) II: Assignment of Bonded Parameters and Partial Atomic Charges
K. Vanommeslaeghe et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2012)
Automation of the CHARMM General Force Field (CGenFF) I: Bond Perception and Atom Typing
K. Vanommeslaeghe et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2012)
Extension of the CHARMM general force field to sulfonyl-containing compounds and its utility in biomolecular simulations
Wenbo Yu et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2012)
Crystal structure of the predicted phospholipase LYPLAL1 reveals unexpected functional plasticity despite close relationship to acyl protein thioesterases
Marco Buerger et al.
JOURNAL OF LIPID RESEARCH (2012)
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
Robert A. Scott et al.
NATURE GENETICS (2012)
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
Alisa K. Manning et al.
NATURE GENETICS (2012)
The pharmacological landscape and therapeutic potential of serine hydrolases
Daniel A. Bachovchin et al.
NATURE REVIEWS DRUG DISCOVERY (2012)
Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals
Zari Dastani et al.
PLOS GENETICS (2012)
The Metabolic Serine Hydrolases and Their Functions in Mammalian Physiology and Disease
Jonathan Z. Long et al.
CHEMICAL REVIEWS (2011)
Activity-based probes: discovering new biology and new drug targets
William P. Heal et al.
CHEMICAL SOCIETY REVIEWS (2011)
The NumPy Array: A Structure for Efficient Numerical Computation
Stefan van der Walt et al.
COMPUTING IN SCIENCE & ENGINEERING (2011)
Software News and Updates MDAnalysis: A Toolkit for the Analysis of Molecular Dynamics Simulations
Naveen Michaud-Agrawal et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2011)
Genome-Wide Association Analysis Identifies Variants Associated with Nonalcoholic Fatty Liver Disease That Have Distinct Effects on Metabolic Traits
Elizabeth K. Speliotes et al.
PLOS GENETICS (2011)
Activity-based Proteomics of Enzyme Superfamilies: Serine Hydrolases as a Case Study
Gabriel M. Simon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
Iris M. Heid et al.
NATURE GENETICS (2010)
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
Elizabeth K. Speliotes et al.
NATURE GENETICS (2010)
Superfamily-wide portrait of serine hydrolase inhibition achieved by library-versus-library screening
Daniel A. Bachovchin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
CHARMM: The Biomolecular Simulation Program
B. R. Brooks et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2009)
Identification of selective inhibitors of uncharacterized enzymes by high-throughput screening with fluorescent activity-based probes
Daniel A. Bachovchin et al.
NATURE BIOTECHNOLOGY (2009)
Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution
Cecilia M. Lindgren et al.
PLOS GENETICS (2009)
Activity-based protein profiling: From enzyme chemistry
Benjamin F. Cravatt et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2008)
Software news and updates - CHARNIM-GUI: A web-based grraphical user interface for CHARMM
Sunhwan Jo et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2008)
A functional proteomic strategy to discover inhibitors for uncharacterized hydrolases
Weiwei Li et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)
Tagging and detection strategies for activity-based proteomics
Amir M. Sadaghiani et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2007)
Adipose triglyceridelipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome
Achim Lass et al.
CELL METABOLISM (2006)
Discovery of potent, selective, and orally bioavailable pyridone-based dipeptidyl peptidase-4 inhibitors
JY Xu et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
Scalable molecular dynamics with NAMD
JC Phillips et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2005)
A streamlined platform for high-content functional proteomics of primary human specimens
N Jessani et al.
NATURE METHODS (2005)
The development and application of methods for activity-based protein profiling
N Jessani et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2004)
Carcinoma and stromal enzyme activity profiles associated with breast tumor growth in vivo
N Jessani et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Discovering potent and selective reversible inhibitors of enzymes in complex proteomes
D Leung et al.
NATURE BIOTECHNOLOGY (2003)
Enzyme activity profiles of the secreted and membrane proteome that depict cancer cell invasiveness
N Jessani et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Share Paper
