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Tau Structures
Jesus Avila et al.
FRONTIERS IN AGING NEUROSCIENCE (2016)
Preclinical Assessment of Young Blood Plasma for Alzheimer Disease
Jinte Middeldorp et al.
JAMA NEUROLOGY (2016)
Calcium-Sensing Receptors of Human Neural Cells Play Crucial Roles in Alzheimer's Disease
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LRP1 expression in microglia is protective during CNS autoimmunity
Tzu-Ying Chuang et al.
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Meryem Tardivel et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2016)
Validating GWAS-Identified Risk Loci for Alzheimer's Disease in Han Chinese Populations
Hui-Zhen Wang et al.
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Acetylation mimic of lysine 280 exacerbates human Tau neurotoxicity in vivo
Marianna Karina Gorsky et al.
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Antibiotic-induced perturbations in gut microbial diversity influences neuro-inflammation and amyloidosis in a murine model of Alzheimer's disease
Myles R. Minter et al.
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Christina M. Lill et al.
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Badri N. Vardarajan et al.
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Fyn inhibition rescues established memory and synapse loss in Alzheimer mice
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ANNALS OF NEUROLOGY (2015)
Inflammation in Alzheimer's Disease and Molecular Genetics: Recent Update
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Nicole Maphis et al.
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Lieve Desbonnet et al.
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Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis
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TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer's Disease Model
Yaming Wang et al.
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Downregulation of the microtubule associated protein Tau impairs process outgrowth and myelin basic protein mRNA transport in oligodendrocytes
Veronika Seiberlich et al.
GLIA (2015)
The twenty-four KDa C-terminal tau fragment increases with aging in tauopathy mice: implications of prion-like properties
Shin-Ei Matsumoto et al.
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Prion-Protein-interacting Amyloid-β Oligomers of High Molecular Weight Are Tightly Correlated with Memory Impairment in Multiple Alzheimer Mouse Models
Mikhail A. Kostylev et al.
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Tau reduction prevents Aβ-induced axonal transport deficits by blocking activation of GSK3β
Keith A. Vossel et al.
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Studies on the ATP Binding Site of Fyn Kinase for the Identification of New Inhibitors and Their Evaluation as Potential Agents against Tauopathies and Tumors
Cristina Tintori et al.
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Pre-synaptic C-terminal truncated tau is released from cortical synapses in Alzheimer's disease
Sophie Sokolow et al.
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Tau Immunotherapy Modulates Both Pathological Tau and Upstream Amyloid Pathology in an Alzheimer's Disease Mouse Model
Diana L. Castillo-Carranza et al.
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Tau Phosphorylation at Serine 396 Residue Is Required for Hippocampal LTD
Philip Regan et al.
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Porphyromonas gingivalis Periodontal Infection and Its Putative Links with Alzheimer's Disease
Sim K. Singhrao et al.
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Kaoru Yamada et al.
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Zhiqiang Xu et al.
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Manasi Malik et al.
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η-Secretase processing of APP inhibits neuronal activity in the hippocampus
Michael Willem et al.
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Antoine Louveau et al.
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Sang-Won Min et al.
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Tau post-translational modifications in wild-type and human amyloid precursor protein transgenic mice
Meaghan Morris et al.
NATURE NEUROSCIENCE (2015)
Depletion of microglia and inhibition of exosome synthesis halt tau propagation
Hirohide Asai et al.
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Clearance systems in the brain-implications for Alzheimer disease
Jenna M. Tarasoff-Conway et al.
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Michael V. Sofroniew
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Stress, the Stress System and the Role of Glucocorticoids
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Appoptosin-Mediated Caspase Cleavage of Tau Contributes to Progressive Supranuclear Palsy Pathogenesis
Yingjun Zhao et al.
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Blood-Brain Barrier Breakdown in the Aging Human Hippocampus
Axel Montagne et al.
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Eleonore Beurel et al.
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Tau stabilizes microtubules by binding at the interface between tubulin heterodimers
Harindranath Kadavath et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Conversion of psychological stress into cellular stress response: Roles of the sigma-1 receptor in the process
Teruo Hayashi
PSYCHIATRY AND CLINICAL NEUROSCIENCES (2015)
Microglial internalization and degradation of pathological tau is enhanced by an anti-tau monoclonal antibody
Wenjie Luo et al.
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Lactobacillus fermentum NS9 restores the antibiotic induced physiological and psychological abnormalities in rats
T. Wang et al.
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R47H Variant of TREM2 Associated With Alzheimer Disease in a Large Late-Onset Family Clinical, Genetic, and Neuropathological Study
Olena Korvatska et al.
JAMA NEUROLOGY (2015)
Metabolic Risk Factors of Sporadic Alzheimer's Disease: Implications in the Pathology, Pathogenesis and Treatment
Sasanka Chakrabarti et al.
AGING AND DISEASE (2015)
Cerebral Amyloid Angiopathy: Emerging Concepts
Masahito Yamada
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Distinct Chronology of Neuronal Cell Cycle Re-Entry and Tau Pathology in the 3xTg-AD Mouse Model and Alzheimer's Disease Patients
Alex C. Hradek et al.
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The Role of SORL1 in Alzheimer's Disease
Rui-Hua Yin et al.
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Axonal Transport Defects in Alzheimer's Disease
Zi-Xuan Wang et al.
MOLECULAR NEUROBIOLOGY (2015)
A Reduced Astrocyte Response to β-Amyloid Plaques in the Ageing Brain Associates with Cognitive Impairment
Ryan Mathur et al.
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Herpes Viruses Increase the Risk of Alzheimer's Disease: A Meta-Analysis
Ariah J. Steel et al.
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A Phase II Trial of Tideglusib in Alzheimer's Disease
Simon Lovestone et al.
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Transcriptomics Profiling of Alzheimer's Disease Reveal Neurovascular Defects, Altered Amyloid-beta Homeostasis, and Deregulated Expression of Long Noncoding RNAs
Marco Magistri et al.
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John F. Crary et al.
ACTA NEUROPATHOLOGICA (2014)
Meta-analysis of Genome-wide Association Studies Identifies 1q22 as a Susceptibility Locus for Intracerebral Hemorrhage
Daniel Woo et al.
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Eric Karran et al.
ANNALS OF NEUROLOGY (2014)
Lysine methylation is an endogenous post-translational modification of tau protein in human brain and a modulator of aggregation propensity
Kristen E. Funk et al.
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Amyloid-β(1-42) protofibrils stimulate a quantum of secreted IL-1β despite significant intracellular IL-1β accumulation in microglia
Shana E. Terrill-Usery et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2014)
March separate, strike together - Role of phosphorylated TAU in mitochondrial dysfunction in Alzheimer's disease
Anne Eckert et al.
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Axotrophin/MARCH7 acts as an E3 ubiquitin ligase and ubiquitinates tau protein in vitro impairing microtubule binding
Katharina Flach et al.
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Russell H. Swerdlow et al.
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Xinglong Wang et al.
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Wim J. Riedel
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Jared M. Cregg et al.
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Herbert Tilg et al.
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Casey Cook et al.
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Michael C. Phillips
IUBMB LIFE (2014)
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Claire H. Michel et al.
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Neuronal activity regulates extracellular tau in vivo
Kaoru Yamada et al.
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Melissa A. Bradley-Whitman et al.
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Ye Zhang et al.
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Peripheral Administration of a Humanized Anti-PrP Antibody Blocks Alzheimer's Disease Aβ Synaptotoxicity
Igor Klyubin et al.
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Activity-Dependent Tau Protein Translocation to Excitatory Synapse Is Disrupted by Exposure to Amyloid-Beta Oligomers
Marie Lise Frandemiche et al.
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Wei Tang et al.
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M. W. Miller et al.
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Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice
Saul A. Villeda et al.
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Zhentao Zhang et al.
NATURE MEDICINE (2014)
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Philip L. De Jager et al.
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Tariq Ahmed et al.
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Sleep deprivation impairs memory, tau metabolism, and synaptic integrity of a mouse model of Alzheimer's disease with plaques and tangles
Antonio Di Meco et al.
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Riley Bove et al.
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Michael L. Alosco et al.
OBESITY (2014)
Microtubule-associated protein tau is essential for long-term depression in the hippocampus
Tetsuya Kimura et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)
SUMOylation at K340 inhibits tau degradation through deregulating its phosphorylation and ubiquitination
Hong-Bin Luo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Blockade of EphA4 signaling ameliorates hippocampal synaptic dysfunctions in mouse models of Alzheimer's disease
Amy K. Y. Fu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Sorting Nexin 27 Regulates Aβ Production through Modulating γ-Secretase Activity
Xin Wang et al.
CELL REPORTS (2014)
Herpes simplex virus type 1 and Alzheimer's disease: increasing evidence for a major role of the virus
Ruth F. Itzhaki
FRONTIERS IN AGING NEUROSCIENCE (2014)
Elevation of brain magnesium prevents synaptic loss and reverses cognitive deficits in Alzheimer's disease mouse model
Wei Li et al.
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Effect of 1 Night of Total Sleep Deprivation on Cerebrospinal Fluid β-Amyloid 42 in Healthy Middle-Aged Men A Randomized Clinical Trial
Sharon Ooms et al.
JAMA NEUROLOGY (2014)
Amyloid-β and Tau The Trigger and Bullet in Alzheimer Disease Pathogenesis
George S. Bloom
JAMA NEUROLOGY (2014)
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James P. Fuller et al.
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Kellen Voss et al.
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Miranda M. Lim et al.
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Beyond allostatic load: Rethinking the role of stress in regulating human development
Bruce J. Ellis et al.
DEVELOPMENT AND PSYCHOPATHOLOGY (2014)
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Bo-Ryoung Choi et al.
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Probing copper/tau protein interactions electrochemically
Sanela Martic et al.
ANALYTICAL BIOCHEMISTRY (2013)
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Martial Ruat et al.
BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM (2013)
Calcium-sensing receptor antagonist (calcilytic) NPS 2143 specifically blocks the increased secretion of endogenous Aβ42 prompted by exogenous fibrillary or soluble Aβ25-35 in human cortical astrocytes and neurons-Therapeutic relevance to Alzheimer's disease
Ubaldo Armato et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2013)
Chronic mild sleep restriction accentuates contextual memory impairments, and accumulations of cortical Aβ and pTau in a mouse model of Alzheimer's disease
Sarah M. Rothman et al.
BRAIN RESEARCH (2013)
Physiological release of endogenous tau is stimulated by neuronal activity
Amy M. Pooler et al.
EMBO REPORTS (2013)
Small Misfolded Tau Species Are Internalized via Bulk Endocytosis and Anterogradely and Retrogradely Transported in Neurons
Jessica W. Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
FcγRIIb mediates amyloid-β neurotoxicity and memory impairment in Alzheimer's disease
Tae-In Kam et al.
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Amyloid-β-Induced Astrocytic Phagocytosis is Mediated by CD36, CD47 and RAGE
Raasay S. Jones et al.
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Cerebrospinal Fluid Tau Cleaved by Caspase-6 Reflects Brain Levels and Cognition in Aging and Alzheimer Disease
Jasmine Ramcharitar et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2013)
Amyloid-β1-42 Slows Clearance of Synaptically Released Glutamate by Mislocalizing Astrocytic GLT-1
Annalisa Scimemi et al.
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Synthetic Tau Fibrils Mediate Transmission of Neurofibrillary Tangles in a Transgenic Mouse Model of Alzheimer's-Like Tauopathy
Michiyo Iba et al.
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Neuronal Clearance of Amyloid-β by Endocytic Receptor LRP1
Takahisa Kanekiyo et al.
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A Transgenic Alzheimer Rat with Plaques, Tau Pathology, Behavioral Impairment, Oligomeric Aβ, and Frank Neuronal Loss
Robert M. Cohen et al.
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G. Clarke et al.
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Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology
J. Chapuis et al.
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NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice
Michael T. Heneka et al.
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Natural RNA circles function as efficient microRNA sponges
Thomas B. Hansen et al.
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Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
Jean-Charles Lambert et al.
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Chia-Chan Liu et al.
NATURE REVIEWS NEUROLOGY (2013)
The microtubule-associated tau protein has intrinsic acetyltransferase activity
Todd J. Cohen et al.
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Blue-green algae or cyanobacteria in the intestinal micro-flora may produce neurotoxins such as Beta-N-Methylamino-L-Alanine (BMAA) which may be related to development of amyotrophic lateral sclerosis, Alzheimer's disease and Parkinson-Dementia-Complex in humans and Equine Motor Neuron Disease in Horses
Steven R. Brenner
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Pulse wave velocity is associated with β-amyloid deposition in the brains of very elderly adults
Timothy M. Hughes et al.
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Alzheimer's Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta
Ana Griciuc et al.
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SORL1 Is Genetically Associated with Late-Onset Alzheimer's Disease in Japanese, Koreans and Caucasians
Akinori Miyashita et al.
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Characterization of Novel CSF Tau and ptau Biomarkers for Alzheimer's Disease
Jere E. Meredith et al.
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α7 Nicotinic Receptor-Mediated Astrocytic Gliotransmitter Release: Aβ Effects in a Preclinical Alzheimer's Mouse Model
Tiina Maria Pirttimaki et al.
PLOS ONE (2013)
Expression of Tau40 Induces Activation of Cultured Rat Microglial Cells
Lu Wang et al.
PLOS ONE (2013)
Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss
Maria Talantova et al.
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Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds
Brandon B. Holmes et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Promiscuous Alzheimer's Amyloid: Yet Another Partner
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Sleep Drives Metabolite Clearance from the Adult Brain
Lulu Xie et al.
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Andrew S. P. Lim et al.
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Masashi Abe et al.
TRENDS IN CELL BIOLOGY (2013)
Amyloid-β nanotubes are associated with prion protein-dependent synaptotoxicity
Andrew J. Nicoll et al.
NATURE COMMUNICATIONS (2013)
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Steve Horvath
GENOME BIOLOGY (2013)
Dual modification of Alzheimer's disease PHF-tau protein by lysine methylation and ubiquitylation: a mass spectrometry approach
Stefani N. Thomas et al.
ACTA NEUROPATHOLOGICA (2012)
Lack of Tau Proteins Rescues Neuronal Cell Death and Decreases Amyloidogenic Processing of APP in APP/PS1 Mice
Karelle Leroy et al.
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Daniela Riccardi et al.
ANNUAL REVIEW OF PHYSIOLOGY, VOL 74 (2012)
Exercise Engagement as a Moderator of the Effects of APOE Genotype on Amyloid Deposition
Denise Head et al.
ARCHIVES OF NEUROLOGY (2012)
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Ilaria Lamberto et al.
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Sarah M. Ward et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2012)
Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies
David J. Irwin et al.
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Wojciech Danysz et al.
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The role of astrocytes in amyloid β-protein toxicity and clearance
Dietmar Rudolf Thal
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Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimers disease neurons: implications for mitochondrial dysfunction and neuronal damage
Maria Manczak et al.
HUMAN MOLECULAR GENETICS (2012)
Ephs and ephrins: Emerging therapeutic targets in neuropathology
Benjamin K. Attwood et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2012)
Exosome-associated Tau Is Secreted in Tauopathy Models and Is Selectively Phosphorylated in Cerebrospinal Fluid in Early Alzheimer Disease
Sudad Saman et al.
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CutA Divalent Cation Tolerance Homolog (Escherichia coli) (CUTA) Regulates β-Cleavage of β-Amyloid Precursor Protein (APP) through Interacting with β-Site APP Cleaving Protein 1 (BACE1)
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Paired Helical Filaments from Alzheimer Disease Brain Induce Intracellular Accumulation of Tau Protein in Aggresomes
Ismael Santa-Maria et al.
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CD36 is involved in astrocyte activation and astroglial scar formation
Yi Bao et al.
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TLR2 Is a Primary Receptor for Alzheimer's Amyloid β Peptide To Trigger Neuroinflammatory Activation
Shirong Liu et al.
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Glial cells in (patho)physiology
Vladimir Parpura et al.
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Chronic IL-1β-Mediated Neuroinflammation Mitigates Amyloid Pathology in a Mouse Model of Alzheimer's Disease without Inducing Overt Neurodegeneration
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Appoptosin is a Novel Pro-Apoptotic Protein and Mediates Cell Death in Neurodegeneration
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Possible neuroprotective property of nicotinic acetylcholine receptors in association with predominant upregulation of glial cell line-derived neurotrophic factor in astrocytes
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Sorting nexin 12 interacts with BACE1 and regulates BACE1-mediated APP processing
Yonghao Zhao et al.
MOLECULAR NEURODEGENERATION (2012)
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Juan D. Pita-Almenar et al.
LEARNING & MEMORY (2012)
Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development
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A mutation in APP protects against Alzheimer's disease and age-related cognitive decline
Thorlakur Jonsson et al.
NATURE (2012)
Apolipoprotein E controls cerebrovascular integrity via cyclophilin A
Robert D. Bell et al.
NATURE (2012)
An epigenetic blockade of cognitive functions in the neurodegenerating brain
Johannes Graeff et al.
NATURE (2012)
Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export
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NATURE MEDICINE (2012)
Apolipoprotein E ε4-related thickening of the cerebral cortex modulates selective attention
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OVEREXPRESSION OF CELLULAR PRION PROTEIN (PRPC) PREVENTS COGNITIVE DYSFUNCTION AND APOPTOTIC NEURONAL CELL DEATH INDUCED BY AMYLOID-β (AB1-40) ADMINISTRATION IN MICE
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Trans-Synaptic Spread of Tau Pathology In Vivo
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Amyloid Precursor Protein and Proinflammatory Changes Are Regulated in Brain and Adipose Tissue in a Murine Model of High Fat Diet-Induced Obesity
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Expression of Novel Alzheimer's Disease Risk Genes in Control and Alzheimer's Disease Brains
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COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)
Soluble forms of tau are toxic in Alzheimer's disease
Katherine J. Kopeikina et al.
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Robert S. Wilson et al.
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Tau Accumulation Causes Mitochondrial Distribution Deficits in Neurons in a Mouse Model of Tauopathy and in Human Alzheimer's Disease Brain
Katherine J. Kopeikina et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
Reactive Glia not only Associates with Plaques but also Parallels Tangles in Alzheimer's Disease
Alberto Serrano-Pozo et al.
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Mapping O-GlcNAc modification sites on tau and generation of a site-specific O-GlcNAc tau antibody
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Amyloid Precursor Protein Processing and Alzheimer's Disease
Richard J. O'Brien et al.
ANNUAL REVIEW OF NEUROSCIENCE, VOL 34 (2011)
Meta-analysis of the Association Between Variants in SORL1 and Alzheimer Disease
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Synergistic Interactions between Repeats in Tau Protein and Aβ Amyloids May Be Responsible for Accelerated Aggregation via Polymorphic States
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Activation of CD47 Receptors Causes Proliferation of Human Astrocytoma but Not Normal Astrocytes via an Akt-Dependent Pathway
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Masashi Kitazawa et al.
JOURNAL OF IMMUNOLOGY (2011)
TLR4 mutation reduces microglial activation, increases Aβ deposits and exacerbates cognitive deficits in a mouse model of Alzheimer's disease
Min Song et al.
JOURNAL OF NEUROINFLAMMATION (2011)
CSF amyloid β38 as a novel diagnostic marker for dementia with Lewy bodies
Ezra Mulugeta et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2011)
Stages of the Pathologic Process in Alzheimer Disease: Age Categories From 1 to 100 Years
Heiko Braak et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2011)
In Vivo Microdialysis Reveals Age-Dependent Decrease of Brain Interstitial Fluid Tau Levels in P301S Human Tau Transgenic Mice
Kaoru Yamada et al.
JOURNAL OF NEUROSCIENCE (2011)
Apolipoprotein E in Alzheimer's disease and other neurological disorders
Philip B. Verghese et al.
LANCET NEUROLOGY (2011)
Calpain-Mediated Tau Cleavage: A Mechanism Leading to Neurodegeneration Shared by Multiple Tauopathies
Adriana Ferreira et al.
MOLECULAR MEDICINE (2011)
Microglial phagocytosis induced by fibrillar β-amyloid is attenuated by oligomeric β-amyloid: implications for Alzheimer's disease
Xiao-dong Pan et al.
MOLECULAR NEURODEGENERATION (2011)
Reversing EphB2 depletion rescues cognitive functions in Alzheimer model
Moustapha Cisse et al.
NATURE (2011)
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
Adam C. Naj et al.
NATURE GENETICS (2011)
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
Paul Hollingworth et al.
NATURE GENETICS (2011)
MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-alpha-PU.1 pathway
Eugene D. Ponomarev et al.
NATURE MEDICINE (2011)
Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
Berislav V. Zlokovic
NATURE REVIEWS NEUROSCIENCE (2011)
Oxidatively modified nucleic acids in preclinical Alzheimer's disease (PCAD) brain
Mark A. Lovell et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2011)
Cleavage of Tau by calpain in Alzheimer's disease: the quest for the toxic 17 kD fragment
Sarika Garg et al.
NEUROBIOLOGY OF AGING (2011)
Cyclophilin D deficiency improves mitochondrial function and learning/memory in aging Alzheimer disease mouse model
Heng Du et al.
NEUROBIOLOGY OF AGING (2011)
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K. M. Neufeld et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2011)
ROLE OF Aβ-RECEPTOR FOR ADVANCED GLYCATION ENDPRODUCTS INTERACTION IN OXIDATIVE STRESS AND CYTOSOLIC PHOSPHOLIPASE A2 ACTIVATION IN ASTROCYTES AND CEREBRAL ENDOTHELIAL CELLS
S. Askarova et al.
NEUROSCIENCE (2011)
Insoluble cellular prion protein and its association with prion and Alzheimer diseases
Wen-Quan Zou et al.
PRION (2011)
Serotonin signaling is associated with lower amyloid-β levels and plaques in transgenic mice and humans
John R. Cirrito et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
The acetylation of tau inhibits its function and promotes pathological tau aggregation
Todd J. Cohen et al.
NATURE COMMUNICATIONS (2011)
APP processing in Alzheimer's disease
Yun-Wu Zhang et al.
MOLECULAR BRAIN (2011)
Genetic Variation and Neuroimaging Measures in Alzheimer Disease
Alessandro Biffi et al.
ARCHIVES OF NEUROLOGY (2010)
Involvements of the lipid peroxidation product, HNE, in the pathogenesis and progression of Alzheimer's disease
D. Allan Butterfield et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2010)
Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology
Paula I. Moreira et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2010)
Rational therapeutic approaches to progressive supranuclear palsy
Maria Stamelou et al.
BRAIN (2010)
Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models
Lars M. Ittner et al.
CELL (2010)
Proteomic identification of sorting nexin 6 as a negative regulator of BACE1-mediated APP processing
Hirokazu Okada et al.
FASEB JOURNAL (2010)
RAGE-dependent signaling in microglia contributes to neuroinflammation, Aβ accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease
Fang Fang et al.
FASEB JOURNAL (2010)
Secretion of human tau fragments resembling CSF-tau in Alzheimer's disease is modulated by the presence of the exon 2 insert
WonHee Kim et al.
FEBS LETTERS (2010)
Tau Ser262 phosphorylation is critical for Aβ42-induced tau toxicity in a transgenic Drosophila model of Alzheimer's disease
Koichi Iijima et al.
HUMAN MOLECULAR GENETICS (2010)
A Mitocentric View of Alzheimer's Disease Suggests Multi-Faceted Treatments
Gary E. Gibson et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Neuron Specific Toxicity of Oligomeric Amyloid-beta: Role for JUN-Kinase and Oxidative Stress
Philip J. Ebenezer et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Interneuronal Transfer of Human Tau Between Lamprey Central Neurons in situ
WonHee Kim et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Ubiquitin Regulates GGA3-mediated Degradation of BACE1
Eugene L. Kang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Memory Impairment in Transgenic Alzheimer Mice Requires Cellular Prion Protein
David A. Gimbel et al.
JOURNAL OF NEUROSCIENCE (2010)
BACE1 Deficiency Causes Altered Neuronal Activity and Neurodegeneration
Xiangyou Hu et al.
JOURNAL OF NEUROSCIENCE (2010)
Deletion of Tau Attenuates Heat Shock-Induced Injury in Cultured Cortical Neurons
Yanying Miao et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2010)
Diverse Roles of Extracellular Calcium-Sensing Receptor in the Central Nervous System
Sanghamitra Bandyopadhyay et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2010)
Analysis of Human Tau in Cerebrospinal Fluid
Katja Hanisch et al.
JOURNAL OF PROTEOME RESEARCH (2010)
BACE1-/- mice exhibit seizure activity that does not correlate with sodium channel level or axonal localization
Brian D. Hitt et al.
MOLECULAR NEURODEGENERATION (2010)
Caspase activation precedes and leads to tangles
Alix de Calignon et al.
NATURE (2010)
Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy
Sang-Won Min et al.
NEURON (2010)
Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration
Brian R. Hoover et al.
NEURON (2010)
Sleep and episodic memory: A review of the literature in young healthy subjects and potential links between sleep changes and memory impairment observed during aging and Alzheimer's disease
G. Rauchs et al.
REVUE NEUROLOGIQUE (2010)
Altered Histone Acetylation Is Associated with Age-Dependent Memory Impairment in Mice
Shahaf Peleg et al.
SCIENCE (2010)
Tau Reduction Prevents Aβ-Induced Defects in Axonal Transport
Keith A. Vossel et al.
SCIENCE (2010)
TREM2-and DAP12-Dependent Activation of PI3K Requires DAP10 and Is Inhibited by SHIP1
Qisheng Peng et al.
SCIENCE SIGNALING (2010)
Mysterious alpha 6-containing nAChRs: function, pharmacology, and pathophysiology
Ke-chun Yang et al.
ACTA PHARMACOLOGICA SINICA (2009)
Apolipoprotein E-Dependent Accumulation of Alzheimer Disease-Related Lesions Begins in Middle Age
Eloise Kok et al.
ANNALS OF NEUROLOGY (2009)
Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease
Fei Liu et al.
BRAIN (2009)
Calcium-Sensing Receptor (CaSR) in Human Brain's Pathophysiology: Roles in Late-Onset Alzheimer's Disease (LOAD)
Anna Chiarini et al.
CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2009)
Genetic Variation in N-Methyl-D-Aspartate Receptor Subunit NR3A but Not NR3B Influences Susceptibility to Alzheimer's Disease
Hsin-Ping Liu et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2009)
Functional α7-Containing Nicotinic Receptors of NG2-Expressing Cells in the Hippocampus
Mateo Velez-Fort et al.
GLIA (2009)
Propagation of Tau Misfolding from the Outside to the Inside of a Cell
Bess Frost et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Combined CSF tau, p-tau181 and amyloid-β 38/40/42 for diagnosing Alzheimer's disease
Volker Welge et al.
JOURNAL OF NEURAL TRANSMISSION (2009)
Chronic copper exposure exacerbates both amyloid and tau pathology and selectively dysregulates cdk5 in a mouse model of AD
Masashi Kitazawa et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease
Xinglong Wang et al.
JOURNAL OF NEUROSCIENCE (2009)
HDAC2 negatively regulates memory formation and synaptic plasticity
Ji-Song Guan et al.
NATURE (2009)
Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers
Juha Lauren et al.
NATURE (2009)
APP binds DR6 to trigger axon pruning and neuron death via distinct caspases
Anatoly Nikolaev et al.
NATURE (2009)
Transmission and spreading of tauopathy in transgenic mouse brain
Florence Clavaguera et al.
NATURE CELL BIOLOGY (2009)
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
Denise Harold et al.
NATURE GENETICS (2009)
Olfactory behavior and physiology are disrupted in prion protein knockout mice
Claire E. Le Pichon et al.
NATURE NEUROSCIENCE (2009)
Advances in tau-focused drug discovery for Alzheimer's disease and related tauopathies
Kurt R. Brunden et al.
NATURE REVIEWS DRUG DISCOVERY (2009)
Developmental Regulation of TREM2 and DAP12 Expression in the Murine CNS: Implications for Nasu-Hakola Disease
J. Cameron Thrash et al.
NEUROCHEMICAL RESEARCH (2009)
Soluble Oligomers of Amyloid β Protein Facilitate Hippocampal Long-Term Depression by Disrupting Neuronal Glutamate Uptake
Shaomin Li et al.
NEURON (2009)
VASCULAR AMYLOID ALTERS ASTROCYTIC WATER AND POTASSIUM CHANNELS IN MOUSE MODELS AND HUMANS WITH ALZHEIMER'S DISEASE
D. M. Wilcock et al.
NEUROSCIENCE (2009)
Immunoreactivity to Lys63-linked polyubiquitin is a feature of neurodegeneration
Simon Paine et al.
NEUROSCIENCE LETTERS (2009)
Alzheimer's disease, metal ions and metal homeostatic therapy
Paolo Zatta et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2009)
Co-localization of amyloid beta and tau pathology in Alzheimer's disease synaptosomes
Jeffrey A. Fein et al.
AMERICAN JOURNAL OF PATHOLOGY (2008)
Brain reserve and the prevention of dementia
Michael J. Valenzuela
CURRENT OPINION IN PSYCHIATRY (2008)
Amyloid beta peptides and glutamatergic synaptic dysregulation
Kodeeswaran Parameshwaran et al.
EXPERIMENTAL NEUROLOGY (2008)
The ratio of monomeric to aggregated forms of Aβ40 and Aβ42 is an important determinant of amyloid-β aggregation, fibrillogenesis, and toxicity
Asad Jan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Loss of LR11/SORLA Enhances Early Pathology in a Mouse Model of Amyloidosis: Evidence for a Proximal Role in Alzheimer's Disease
Sara E. Dodson et al.
JOURNAL OF NEUROSCIENCE (2008)
Tau exon 10 alternative splicing and tauopathies
Fei Liu et al.
MOLECULAR NEURODEGENERATION (2008)
A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo
Scott A. Yuzwa et al.
NATURE CHEMICAL BIOLOGY (2008)
The NALP3 inflammasome is involved in the innate immune response to amyloid-β
Annett Halle et al.
NATURE IMMUNOLOGY (2008)
Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease
Heng Du et al.
NATURE MEDICINE (2008)
Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
Ganesh M. Shankar et al.
NATURE MEDICINE (2008)
The Mystery and Magic of Glia: A Perspective on Their Roles in Health and Disease
Ben A. Barres
NEURON (2008)
Is there a link between sleep changes and memory in Alzheimer's disease?
Geraldine Rauchs et al.
NEUROREPORT (2008)
Shorter Telomeres May Mark Early Risk of Dementia: Preliminary Analysis of 62 Participants from the Nurses' Health Study
Francine Grodstein et al.
PLOS ONE (2008)
Differential regulation of dynein and kinesin motor proteins by tau
Ram Dixit et al.
SCIENCE (2008)
Alzheimer disease models and human neuropathology: similarities and differences
Charles Duyckaerts et al.
ACTA NEUROPATHOLOGICA (2008)
Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimers disease
Mark A. Lovell et al.
NUCLEIC ACIDS RESEARCH (2007)
Single molecule profiling of tau gene expression in Alzheimer's disease
Chris Conrad et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Expression of APP pathway mRNAs and proteins in Alzheimer's disease
Toshifumi Matsui et al.
BRAIN RESEARCH (2007)
Defective DNA base excision repair in brain from individuals with Alzheimer's disease and amnestic mild cognitive impairment
Lior Weissman et al.
NUCLEIC ACIDS RESEARCH (2007)
The secreted β-amyloid precursor protein ectodomain APPsα is sufficient to rescue the anatomical, behavioral, and electrophysiological abnormalities of APP-deficient mice
Sabine Ring et al.
JOURNAL OF NEUROSCIENCE (2007)
Validation of amyloid-β peptides in CSF diagnosis of neurodegenerative dementias
M. Bibl et al.
MOLECULAR PSYCHIATRY (2007)
Depletion of GGA3 stabilizes BACE and enhances β-secretase activity
Giuseppina Tesco et al.
NEURON (2007)
Reducing endogenous tau ameliorates amyloid β-induced deficits in an Alzheimer's disease mouse model
Erik D. Roberson et al.
SCIENCE (2007)
Aβ oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine
Fernanda G. De Felice et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease
Keith D. Coon et al.
JOURNAL OF CLINICAL PSYCHIATRY (2007)
Calcium-sensing receptor stimulates secretion of an interferon-γ-induced monokine (CXCL10) and monocyte chemoattractant protein-3 in immortalized GnRH neurons
Sanghamitra Bandyopadhyay et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2007)
The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease
Ekaterina Rogaeva et al.
NATURE GENETICS (2007)
Aβ oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease
Pascale N. Lacor et al.
JOURNAL OF NEUROSCIENCE (2007)
Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database
Lars Bertram et al.
NATURE GENETICS (2007)
A beta Oligomers - a decade of discovery
Dominic M. Walsh et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Serum magnesium level and clinical deterioration in Alzheimer's disease
Asli Ece Cilliler et al.
GERONTOLOGY (2007)
Neuroprotective effect of exogenous microglia in global brain ischemia
Fumihiro Imai et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2007)
NMDA receptor function:: subunit composition versus spatial distribution
Georg Koehr
CELL AND TISSUE RESEARCH (2006)
Current knowledge of chromosome 12 susceptibility genes for late-onset Alzheimer's disease
Alessia D'Introno et al.
NEUROBIOLOGY OF AGING (2006)
Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17
Matt Baker et al.
NATURE (2006)
Apolipoprotein E structure: insights into function
Danny M. Hatters et al.
TRENDS IN BIOCHEMICAL SCIENCES (2006)
Deletion of the ubiquitin ligase CHIP leads to the accumulation, but not the aggregation, of both endogenous phospho- and caspase-3-cleaved tau species
Chad A. Dickey et al.
JOURNAL OF NEUROSCIENCE (2006)
CSF amyloid-β-peptides in Alzheimer's disease, dementia with Lewy bodies and Parkinson's disease dementia
M Bibl et al.
BRAIN (2006)
Alzheimer disease-specific conformation of hyperphosphorylated paired helical filament-tau is polyubiquitinated through Lys-48, Lys-11, and Lys-6 ubiquitin conjugation
D Cripps et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Small ubiquitin-like modifier (SUMO) modification of natively unfolded proteins tau and α-synuclein
V Dorval et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Copper binding properties of a tau peptide associated with Alzheimer's disease studied by CD, NMR, and MALDI-TOF MS
QF Ma et al.
PEPTIDES (2006)
Toll-like receptors in central nervous system glial inflammation and homeostasis
T Kielian
JOURNAL OF NEUROSCIENCE RESEARCH (2006)
Shift in the ratio of three-repeat tau and four-repeat tau mRNAs in individual cholinergic basal forebrain neurons in mild cognitive impairment and Alzheimer's disease
SD Ginsberg et al.
JOURNAL OF NEUROCHEMISTRY (2006)
Molecular dissection of the interaction between amyloid precursor protein and its neuronal trafficking receptor SorLA/LR11
OM Andersen et al.
BIOCHEMISTRY (2006)
Ecological and evolutionary forces shaping microbial diversity in the human intestine
RE Ley et al.
CELL (2006)
Aβ and tau form soluble complexes that may promote self aggregation of both into the insoluble forms observed in Alzheimer's disease
JP Guo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Role of genes and environments for explaining Alzheimer disease
M Gatz et al.
ARCHIVES OF GENERAL PSYCHIATRY (2006)
Temporal profile of amyloid-β (Aβ) oligomerization in an in vivo model of Alzheimer disease -: A link between Aβ and tau pathology
S Oddo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Education and dementia: A meta-analytic study
Francisco Caamano-Isorna et al.
NEUROEPIDEMIOLOGY (2006)
Suppression of cyclin-dependent kinase 5 activation by amyloid precursor protein: A novel excitoprotective mechanism involving modulation of tau phosphorylation
P Han et al.
JOURNAL OF NEUROSCIENCE (2005)
Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation
F Liu et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2005)
Roles of Ca2+ and the Ca2+-sensing receptor (CASR) in the expression of inducible NOS (nitric oxide synthase)-2 and its BH4 (tetrahydrobiopterin)-dependent activation in cytokine-stimulated adult human astrocytes
I Dal Pra et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2005)
Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease
M Kitazawa et al.
JOURNAL OF NEUROSCIENCE (2005)
Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein
OM Andersen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Regulation of NMDA receptor trafficking by amyloid-β
EM Snyder et al.
NATURE NEUROSCIENCE (2005)
Tau suppression in a neurodegenerative mouse model improves memory function
K SantaCruz et al.
SCIENCE (2005)
Sites of tau important for aggregation populate β-structure and bind to microtubules and polyanions
MD Mukrasch et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation
JR Babu et al.
JOURNAL OF NEUROCHEMISTRY (2005)
Quantitative analysis of tau isoform transcripts in sporadic tauopathies
JW Connell et al.
MOLECULAR BRAIN RESEARCH (2005)
The generation of a 17 kDa neurotoxic fragment:: An alternative mechanism by which tau mediates β-amyloid-induced neurodegeneration
SY Park et al.
JOURNAL OF NEUROSCIENCE (2005)
Oxidative DNA damage in peripheral leukocytes of mild cognitive impairment and AD patients
L Mighore et al.
NEUROBIOLOGY OF AGING (2005)
Transgenic mouse model of tau pathology in astrocytes leading to nervous system degeneration
MS Forman et al.
JOURNAL OF NEUROSCIENCE (2005)
Accumulation of filamentous tau in the cerebral cortex of human tau R406W transgenic mice
M Ikeda et al.
AMERICAN JOURNAL OF PATHOLOGY (2005)
Gene delivery of human apolipoprotein E alters brain Aβ burden in a mouse model of Alzheimer's disease
JC Dodart et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Transcriptional and conformational changes of the tau molecule in Alzheimer's disease
BT Hyman et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2005)
ABAD directly links Aβ to mitochondrial toxicity in Alzheimer's disease
JW Lustbader et al.
SCIENCE (2004)
Alterations in human tau transcripts correlate with those of neurofilament in sporadic tauopathies
Y Umeda et al.
NEUROSCIENCE LETTERS (2004)
Altered expression levels of the protein phosphatase 2A ABαC enzyme are associated with Alzheimer disease pathology
E Sontag et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2004)
CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation
L Petrucelli et al.
HUMAN MOLECULAR GENETICS (2004)
Tumor necrosis factor death receptor signaling cascade is required for amyloid-β protein-induced neuron death
R Li et al.
JOURNAL OF NEUROSCIENCE (2004)
Biochemical and molecular studies of NMDA receptor subunits NR1/2A/2B in hippocampal subregions throughout progression of Alzheimer's disease pathology
AJ Mishizen-Eberz et al.
NEUROBIOLOGY OF DISEASE (2004)
Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs
JK Olson et al.
JOURNAL OF IMMUNOLOGY (2004)
Early N-terminal changes and caspase-6 cleavage of tau in Alzheimer's disease
PM Horowitz et al.
JOURNAL OF NEUROSCIENCE (2004)
Active caspase-6 and caspase-6-cleaved Tau in neuropil threads, neuritic plaques, and neurofibrillary tangles of Alzheimer's disease
HS Guo et al.
AMERICAN JOURNAL OF PATHOLOGY (2004)
Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology
RA Rissman et al.
JOURNAL OF CLINICAL INVESTIGATION (2004)
Pseudophosphorylation and glycation of tau protein enhance but do not trigger fibrillization in vitro
M Necula et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
APOE ε4 allele is associated with reduced cerebrospinal fluid levels of Aβ42
JA Prince et al.
NEUROLOGY (2004)
Eph receptors in the adult brain
Y Yamaguchi et al.
CURRENT OPINION IN NEUROBIOLOGY (2004)
Altered mitogen-activated protein kinase signaling, tau hyperphosphorylation and mild spatial learning dysfunction in transgenic rats expressing the beta-amyloid peptide intracellularly in hippocampal and cortical neurons
V Echeverria et al.
NEUROSCIENCE (2004)
The LPS receptor (CD14) links innate immunity with Alzheimer's disease
K Fassbender et al.
FASEB JOURNAL (2004)
RAGE (Yin) versus LRP (Yang) balance regulates Alzheimer amyloid β-peptide clearance through transport across the blood-brain barrier
R Deane et al.
STROKE (2004)
Soluble form of amyloid precursor protein regulates proliferation of progenitors in the adult subventricular zone
I Caillé et al.
DEVELOPMENT (2004)
Diverse roles of Eph receptors and ephrins in the regulation of cell migration and tissue assembly
A Poliakov et al.
DEVELOPMENTAL CELL (2004)
Neuronal LRP1 functionally associates with postsynaptic proteins and is required for normal motor function in mice
P May et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Alzheimer's missing link?
[Anonymous]
MOLECULAR THERAPY (2003)
The NMDA receptor antagonist memantine as a symptomatological and neuroprotective treatment for Alzheimer's disease: preclinical evidence
W Danysz et al.
INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY (2003)
Caspase cleavage of tau: Linking amyloid and neurofibrillary tangles in Alzheimer's disease
TC Gamblin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Extracellular calcium sensing and signalling
AM Hofer et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)
CD36 mediates the innate host response to β-amyloid
JB El Khoury et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
A collaborative study of the emergence and clinical features of the major depressive syndrome of Alzheimer's disease
GS Zubenko et al.
AMERICAN JOURNAL OF PSYCHIATRY (2003)
Adult mouse astrocytes degrade amyloid-β in vitro and in situ
T Wyss-Coray et al.
NATURE MEDICINE (2003)
Proteasome inhibition by paired helical filament-tau in brains of patients with Alzheimer's disease
S Keck et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Amyloid β plaque-associated proteins C1q and SAP enhance the Aβ1-42 peptide-induced cytokine secretion by adult human microglia in vitro
R Veerhuis et al.
ACTA NEUROPATHOLOGICA (2003)
Control of hippocampal dendritic spine morphology through ephrin-A3/EphA4 signaling
KK Murai et al.
NATURE NEUROSCIENCE (2003)
A CD36-initiated signaling cascade mediates inflammatory effects of β-amyloid
KJ Moore et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Heterogeneous expression of the triggering receptor expressed on myeloid cells-2 on adult murine microglia
CD Schmid et al.
JOURNAL OF NEUROCHEMISTRY (2002)
A survey of Cdk5 activator p35 and p25 levels in Alzheimer's disease brains
HC Tseng et al.
FEBS LETTERS (2002)
Mechanisms and functions of EPH and ephrin signalling
K Kullander et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)
Tau is essential to β-amyloid-induced neurotoxicity
M Rapoport et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Role of glycosylation in hyperphosphorylation of tau in Alzheimer's disease
F Liu et al.
FEBS LETTERS (2002)
Process outgrowth of oligodendrocytes is promoted by interaction of Fyn kinase with the cytoskeletal protein Tau
C Klein et al.
JOURNAL OF NEUROSCIENCE (2002)
Neurofibrillary pathology leads to synaptic loss and not the other way around in Alzheimer disease
Khalid Iqbal et al.
JOURNAL OF ALZHEIMERS DISEASE (2002)
Regulation and differential expression of tau mRNA isoforms as oligodendrocytes mature in vivo: Implications for myelination
P Lopresti
GLIA (2002)
Relationship between the increased cell surface α7 nicotinic receptor expression and neuroprotection induced by several nicotinic receptor agonists
RR Jonnala et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2001)
Involvement of microglial receptor for advanced glycation endproducts (RAGE) in Alzheimer's disease: Identification of a cellular activation mechanism
LF Lue et al.
EXPERIMENTAL NEUROLOGY (2001)
Pathogenic APP mutations near the γ-secretase cleavage site differentially affect Aβ secretion and APP C-terminal fragment stability
C De Jonghe et al.
HUMAN MOLECULAR GENETICS (2001)
Timing and location of nicotinic activity enhances or depresses hippocampal synaptic plasticity
D Ji et al.
NEURON (2001)
GlutamateNMDA receptor NR1 subunit mRNA expression in Alzheimer's disease
MR Hynd et al.
JOURNAL OF NEUROCHEMISTRY (2001)
Amyloid angiopathy and variability in amyloid β deposition is determined by mutation position in presenilin-1-linked Alzheimer's disease
DMA Mann et al.
AMERICAN JOURNAL OF PATHOLOGY (2001)
Tau-66:: evidence for a novel tau conformation in Alzheimer's disease
N Ghoshal et al.
JOURNAL OF NEUROCHEMISTRY (2001)
NMDA receptor subunits: diversity, development and disease
S Cull-Candy et al.
CURRENT OPINION IN NEUROBIOLOGY (2001)
PP2A mRNA expression is quantitatively decreased in Alzheimer's disease hippocampus
V Vogelsberg-Ragaglia et al.
EXPERIMENTAL NEUROLOGY (2001)
Matrix metalloproteinase (MMP) system in brain: identification and characterization of brain-specific MMP highly expressed in cerebellum
Y Sekine-Aizawa et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2001)
Glutamate transporters in neurologic disease
NJ Maragakis et al.
ARCHIVES OF NEUROLOGY (2001)
Scavenger receptor class B type I (SR-BI) mediates adhesion of neonatal murine microglia to fibrillar β-amyloid
J Husemann et al.
JOURNAL OF NEUROIMMUNOLOGY (2001)
Extracellular calcium sensing and extracellular calcium signaling
EM Brown et al.
PHYSIOLOGICAL REVIEWS (2001)
Treatment of sleep disturbance in Alzheimer's disease
SM McCurry et al.
SLEEP MEDICINE REVIEWS (2000)
Modulation of amyloid β-protein clearance and Alzheimer's disease susceptibility by the LDL receptor-related protein pathway
DE Kang et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)
Regulation of secretion of PTHrP by Ca2+-sensing receptor in human astrocytes, astrocytomas, and meningiomas
N Chattopadhyay et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2000)
Allelic association between the D10S1423 marker and Alzheimer's disease in a German population
M Majores et al.
NEUROSCIENCE LETTERS (2000)
Loss-of-function mutations in TYROBP (DAP12) result in a presenile dementia with bone cysts
J Paloneva et al.
NATURE GENETICS (2000)
Assembly of τ protein into Alzheimer paired helical filaments depends on a local sequence motif (306VQIVYK311) forming β structure
M von Bergen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Progressive supranuclear palsy pathology caused by a novel silent mutation in exon 10 of the tau gene -: Expansion of the disease phenotype caused by tau gene mutations
PM Stanford et al.
BRAIN (2000)
Induction of COX-2 and PGE(2) biosynthesis by LL-1 beta is mediated by PKC and mitogen-activated protein kinases in murine astrocytes
E Molina-Holgado et al.
BRITISH JOURNAL OF PHARMACOLOGY (2000)