Journal
MICROBIOLOGY-SGM
Volume 166, Issue 8, Pages 683-694Publisher
MICROBIOLOGY SOC
DOI: 10.1099/mic.0.000944
Keywords
ActinoBase; Actinobacteria; antibiotics; development; methodology; microbial ecology; regulation; specialized metabolites; Streptomyces; symbiosis
Categories
Funding
- Norwich Research Park BBSRC Postdoctoral Training Program Studentships [BB/M011216/1]
- Edge Hill University
- Natural Environment Research Council (NERC) [NE/L002582/1]
- Engineering and Physical Sciences Research Council (EPSRC)
- University of Strathclyde Research Excellence Award (REA) Studentships
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The actinomycetes are Gram-positive bacteria belonging to the order Actinomycetales within the phylum Actinobacteria. They include members with significant economic and medical importance, for example filamentous actinomycetes such as Streptomyces species, which have a propensity to produce a plethora of bioactive secondary metabolites and form symbioses with higher organisms, such as plants and insects. Studying these bacteria is challenging, but also fascinating and very rewarding. As a Microbiology Society initiative, members of the actinomycete research community have been developing a Wikipedia-style resource, called ActinoBase, the purpose of which is to aid in the study of these filamentous bacteria. This review will highlight 10 publications from 2019 that have been of special interest to the ActinoBase community, covering 4 major components of actinomycete research: (i) development and regulation; (ii) specialized metabolites; (iii) ecology and host interactions; and (iv) technology and methodology.
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