Journal
MENDELEEV COMMUNICATIONS
Volume 30, Issue 4, Pages 494-495Publisher
ELSEVIER
DOI: 10.1016/j.mencom.2020.07.029
Keywords
carbenoids; C-H functionalization; diazo compounds; organofluorine compounds; homogeneous catalysis; nitrogen heterocycles; purines
Categories
Funding
- Russian Foundation for Basic Research [19-53-45035]
- Ministry of Science and Higher Education of the Russian Federation
Ask authors/readers for more resources
The consecutive alkylation of 9-isopropyl-6-phenyl-9H-purine with methyl 2-diazo-3,3,3-trifluoropropionate and diethyl diazomalonate proceeds at the phenyl substituent firstly via ortho-C-H activation under chelation-assistance of the purine core, followed by classical electrophilic metal carbenoid insertion to the C-H bond of a malonate moiety.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
