4.7 Article

Circulation of a novel human respiratory syncytial virus Group B genotype during the 2014-2015 season in Catalonia (Spain)

Journal

CLINICAL MICROBIOLOGY AND INFECTION
Volume 22, Issue 1, Pages -

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.cmi.2015.09.013

Keywords

Genotypes; molecular epidemiology; respiratory infection; respiratory syncytial virus; surveillance

Funding

  1. Plan Nacional de I + D + I
  2. Instituto de Salud Carlos III, Sub-direccionGeneral de Redes y Centros de Investigacion Cooperativa, Ministerio Espanol de Economia y Competitividad, Spanish Network for Research in Infectious Diseases [REIPI RD12/0015]
  3. Fondo de Investigacion Sanitaria, Ministerio Espanol de Economia y Competitividad [FIS PI14/01838]
  4. European Regional Development Fund (ERDF)

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Human respiratory syncytial virus (HRSV) is one of the most common viral aetiological agents in the youngest population. In the present study a novel HRSV-B BA genotype is first described based on the phylogenetic analysis of the coding hypervariable region 2 sequences of G protein from strains detected during the 2014-2015 season. Among all strains detected in the last season, 44% belonged to this new genotype. Therefore, it highlights the importance of a continuous HRSV surveillance to monitor the emergence and spread of new genotypes or variants with genetic changes that may affect antigenic and tropism features. (C) 2015 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

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