Journal
MEDICINAL CHEMISTRY RESEARCH
Volume 29, Issue 9, Pages 1553-1578Publisher
SPRINGER BIRKHAUSER
DOI: 10.1007/s00044-020-02595-4
Keywords
Synthesis; Anticonvulsant activity; Epilepsy; Antiepileptic drug
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Epilepsy is one of the most common neurological disorders worldwide and it requires a long-term or life-long treatment. Current standard treatment includes the use of antiepileptic drugs. To date, many organic compounds have been synthesized by chemists as potential antiepileptic drugs and their anticonvulsant properties have been investigated. While evaluating the anticonvulsant activities of these newly synthesized molecules, known antiepileptic drugs are used as reference. Thus, many novel molecules with anticonvulsant properties have been added to the literature. It is clear that these new molecules will be effective in the treatment of epilepsy. In this review, we investigated the synthesis and properties of organic compounds with anticonvulsant properties.
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