Promoting endothelialization of flow-diverting stents: a review

Intracranial flow-diverting (FD) stents have revolutionized the treatment of intracranial aneurysms in recent years, but complications resulting from failed endothelialization can still occur. Approaches to promote endothelialization are understudied, but hold promise in mitigating both short- and long-term complications associated with FD stent insertion. The aim of this review is to highlight the various features of and modifications that have been made to FD stents in order to expedite endothelialization. More specifically, we focus on how endothelialization can be influenced by the stent design, wall apposition, surface modifications, and the inclusion of biological agents.

Automated summary

This review focuses on discussing how to expedite the formation of endothelial cells in the treatment of intracranial aneurysms through stent design, wall apposition, surface modifications, and the use of biological agents, in order to mitigate postoperative complications.