Journal
JOURNAL OF INFECTION AND CHEMOTHERAPY
Volume 26, Issue 12, Pages 1309-1312Publisher
ELSEVIER
DOI: 10.1016/j.jiac.2020.07.010
Keywords
Syphilis; Chancre; Sexually transmitted disease; Non-specific oral ulcers; Early diagnosis
Categories
Funding
- National Natural Science Foundation of China [81771080, 81970949]
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Syphilis, a sexually transmitted disease, can be categorized as acquired syphilis and congenital syphilis, manifesting diverse lesions involving multiple sites. Oral manifestations at the primary stage of acquired syphilis are usually characterized by its short period and non-specific varied presentations. And oral ulcers as initial and the only presentation of syphilis oral lesions are infrequent and occur in less than 2% of patients. Because of its transient nature and variable manifestations which could mimic other oral ulcerative lesions, oral syphilis presenting as sole ulceration at early stage can be easily neglected and rather difficult to diagnose. Herein, we report a 35-year-old female patient manifested a sole atypical ulceration on her upper lip for approximately 1 month. We highlighted the importance of early and accurate diagnosis, focused on the characteristics of oral chancre, and gave an insight to the differential diagnoses, which would be enlightening and useful in clinical practice. (c) 2020 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
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