The pollution profiles and human exposure risks of chlorinated and brominated PAHs in indoor dusts from e-waste dismantling workshops: Comparison of GC-MS, GC-MS/MS and GC x GC-MS/MS determination methods

The toxicities of some chlorinated and brominated polycyclic aromatic hydrocarbons (X-PAHs) are higher than their corresponding parent PAHs. However, the identification and quantitation of X-PAHs in environment are still changeable and limitedly reported. To develop a robust method for routine analysis of X-PAHs in environmental samples, the determination of 34 X-PAHs was performed and compared using different instruments, including gas chromatography-mass spectrometry (GC-MS), gas chromatography-tandem mass spectrometry (GC-MS/MS) in both electron ionization (EI) and negative chemical ionization (NCI) modes, and comprehensive two-dimensional gas chromatograph-tandem mass spectrometer (GC x GC-MS/MS). GC-EIMS/MS possessed the highest sensitivity with method detection limits of 2.00-40.0 and 2.00-20.0 pg/g dry weight (dw) for Cl-PAHs and Br-PAHs, respectively. This validated method was then applied to analyze X-PAHs in indoor dusts from a typical e-waste dismantling workshop, and the concentrations of Sigma Br-18-PAHs (8.80-399 ng/g dw) were higher than Sigma Cl-16-PAHs (7.91-137 ng/g dw). The toxicity equivalency quantities (TEQs) of Cl-PAHs at e-waste dismantling workshop and Br-PAHs at raw materials crushing workshop showed the highest values of 176 and 453 pg.TEQ/g, respectively. Cl-PAHs and Br-PAHs posed a potential health risk to workers through dust ingestion in workshops. Further attention should be payed to the formation mechanism of X-PAHs and the health risk.