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Nanonutraceuticals: A way towards modern therapeutics in healthcare

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ELSEVIER
DOI: 10.1016/j.jddst.2020.101838

Keywords

Nanotechnology; Nanonutraceuticals; Liposomes; Polymeric nanoparticles; Biological applications; Regulatory bodies

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In the present day of modern medicine, the potential of nanotechnology expresses beneficial applications in the fields of cosmetics, food engineering and technology, pharma industries, etc. Nutraceuticals are the non-toxic food components, extracted from various food compounds for the prevention and cure of diseases. Low solubility, less bioavailability, short-term stability, high dose, poor release profile and first-pass metabolism are considered as limitations of nutraceuticals. To overcome these issues, nanonutraceuticals show advantages for active and passive delivery systems. Immense studies have been performed in the development of nano-technology and nanocarrier-based systems to exploit their potential applications and significant versatility. Hence, the objective of this review article is to study the applications of nanonutraceutical in the area of healthcare for the treatment and management of different conditions like cancer, diabetes, obesity, inflammation, Parkinsonism, Alzheimer's disease, etc. The polymeric-and lipid-based nutraceuticals act as nanocarriers that are essential imperative tools for monitoring various diseases and therapies for effective treatment. Nanonutraceuticals conveniently penetrate cellular membranes at a specific site without undergoing degradation in the gastrointestinal fluids. The overall aim of this article is to provide a straightforward approach of nano-nutraceuticals as an emerging carrier for pharmaceutical formulations.

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