Antimicrobial resistance: Concerns of healthcare providers and people with CF

Background: Chronic lung infections and their treatment pose risks for the development of antimicro-bial resistance (AMR) in people with cystic fibrosis (PWCF). In this study, we evaluated the attitudes of healthcare providers' (HCP) and PWCF or their parents' toward AMR within the international CF commu-nity. Methods: HCP and PWCF identified through listservs and CF-related organizations were asked to com-plete an AMR centered survey, with additional questions on antimicrobial stewardship (AMS) for HCP. Descriptive analyses are reported. Results: The responding 443 HCP and 464 PWCF/Parents were from 30 and 25 countries, respec-tively. Sixty-two percent of HCP and 56% of PWCF stated they were very concerned about AMR, with Pseudomonas spp. and Burkholderia spp. considered the most concerning organisms for both HCP and PWCF/Parents. Non-tuberculous mycobacteria were of greater concern to HCP compared to PWCF/Parents. There was a discrepancy regarding AMR education to PWCF, with 80% of HCP stating having discussed this with PWCF/Parents, but only 50% of PWCF recalling such discussions. Conclusion: These results highlight that AMR is relevant to CF HCP and PWCF internationally, indicating that educational tools and research are warranted. (c) 2020 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved.

Automated summary

The study evaluated the attitudes of healthcare providers and people with cystic fibrosis or their parents towards antimicrobial resistance (AMR) internationally. Findings showed that both groups are concerned about AMR, with Pseudomonas spp. and Burkholderia spp. being the most concerning organisms. There was a discrepancy in AMR education discussions between healthcare providers and people with cystic fibrosis.