Journal
CLINICAL CANCER RESEARCH
Volume 23, Issue 1, Pages 3-5Publisher
AMER ASSOC CANCER RESEARCH
DOI: 10.1158/1078-0432.CCR-16-2322
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- Italian Association for Cancer Research (AIRC) [15627]
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In this issue of Clinical Cancer Research, evidence is provided on how to avoid cardiotoxicity when targeting hERG K+ channel for cancer therapy. hERG regulates different aspects of neoplastic progression. Although its blockade has effective anticancer effects in experimental models, it may lead to fatal arrhythmias in humans. (C) 2016 AACR.
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