Journal
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
Volume 109, Issue 6, Pages 821-828Publisher
WILEY
DOI: 10.1002/jbm.a.37069
Keywords
cytotoxicity; hydroxyapatite; precipitation; substitution
Funding
- Indian Council of Medical Research [35/14/2011-BMS]
- Department of Science and Technology
- University Grants Commission
Ask authors/readers for more resources
This study investigates the potential substitutions of lanthanum and praseodymium in hydroxyapatite, confirming their presence, phase purity, and antibacterial efficiency through analytical techniques.
Hydroxyapatite (HAP) forms the main inorganic component of natural bone and hence has been widely use in implant applications. Ionic substitutions in apatite also gains enormous interest during the recent years due to the crucial role played by these elements in the biological process. In this context, the least investigated elements namely lanthanum (La3+) and praseodymium (Pr3+) have been selected as a potential substitutions in apatite. The results from the analytical techniques confirm the phase purity of the HAP and its ability holds the substitutions at its lattice. Morphological analysis unveils the presence of agglomerated spheroids notwithstanding the ion concentration of substituents. EDX spectra affirm the presence of La and Pr alongside the determined Ca/P atomic ratio of 1.67. La(3+)and Pr(3+)presence envisaged the good antibacterial efficiency against the tested microbes and further demonstrated the biocompatibility nature from the cytotoxicity analysis.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available