4.5 Article

Glutamine Antagonist JHU-083 Normalizes Aberrant Hippocampal Glutaminase Activity and Improves Cognition in APOE4 Mice

Related references

Note: Only part of the references are listed.
Article Immunology

Glial activation and inflammation along the Alzheimer's disease continuum

Kaja Nordengen et al.

JOURNAL OF NEUROINFLAMMATION (2019)

Review Pharmacology & Pharmacy

Gene-environment interactions in Alzheimer's disease: A potential path to precision medicine

Aseel Eid et al.

PHARMACOLOGY & THERAPEUTICS (2019)

Article Multidisciplinary Sciences

MRI demonstrates glutamine antagonist-mediated reversal of cerebral malaria pathology in mice

Brittany A. Riggle et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Review Geriatrics & Gerontology

Clinical PET Imaging of Microglial Activation: Implications for Microglial Therapeutics in Alzheimer's Disease

Zhiwei Shen et al.

FRONTIERS IN AGING NEUROSCIENCE (2018)

Review Neurosciences

Role of Glutamate and NMDA Receptors in Alzheimer's Disease

Rui Wang et al.

JOURNAL OF ALZHEIMERS DISEASE (2017)

Article Neurosciences

Increased BACE1 activity inhibits peripheral nerve regeneration after injury

Carolyn Tallon et al.

NEUROBIOLOGY OF DISEASE (2017)

Article Neurosciences

ApoE4 Accelerates Early Seeding of Amyloid Pathology

Chia-Chen Liu et al.

NEURON (2017)

Article Multidisciplinary Sciences

Sensory and autonomic function and structure in footpads of a diabetic mouse model

Ying Liu et al.

SCIENTIFIC REPORTS (2017)

Article Neurosciences

Identification and modification of amyloid-independent phenotypes of APOE4 mice

Amanda M. DiBattista et al.

EXPERIMENTAL NEUROLOGY (2016)

Review Multidisciplinary Sciences

How neuroinflammation contributes to neurodegeneration

Richard M. Ransohoff

SCIENCE (2016)

Article Neurosciences

Cell type- and brain region-resolved mouse brain proteome

Kirti Sharma et al.

NATURE NEUROSCIENCE (2015)

Article Multidisciplinary Sciences

Targeting glutamine metabolism rescues mice from late-stage cerebral malaria

Emile B. Gordon et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Biochemistry & Molecular Biology

Small molecule glutaminase inhibitors block glutamate release from stimulated microglia

Ajit G. Thomas et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)

Article Immunology

Human APOE4 increases microglia reactivity at Aβ plaques in a mouse model of Aβ deposition

Gustavo A. Rodriguez et al.

JOURNAL OF NEUROINFLAMMATION (2014)

Article Biochemistry & Molecular Biology

APOE genotype affects the pre-synaptic compartment of glutamatergic nerve terminals

Sonya B. Dumanis et al.

JOURNAL OF NEUROCHEMISTRY (2013)

Article Multidisciplinary Sciences

Inhibition of Glutamate Carboxypeptidase II (GCPII) activity as a treatment for cognitive impairment in multiple sclerosis

Kristen A. Rahn et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Medicine, Research & Experimental

Apolipoprotein E and Apolipoprotein E Receptors: Normal Biology and Roles in Alzheimer Disease

David M. Holtzman et al.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)

Review Cell Biology

Cross-Talk between Apolipoprotein E and Cytokines

Hongliang Zhang et al.

MEDIATORS OF INFLAMMATION (2011)

Article Neurosciences

Rett Syndrome Microglia Damage Dendrites and Synapses by the Elevated Release of Glutamate

Izumi Maezawa et al.

JOURNAL OF NEUROSCIENCE (2010)

Article Medicine, General & Internal

Blockade of Glutamate Release from Microglia Attenuates Experimental Autoimmune Encephalomyelitis in Mice

Jin Shijie et al.

TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE (2009)

Article Biochemistry & Molecular Biology

Glutamate production by HIV-1 infected human macrophage is blocked by the inhibition of glutaminase

Nathan Erdmann et al.

JOURNAL OF NEUROCHEMISTRY (2007)

Article Biochemistry & Molecular Biology

Tumor necrosis factor-α induces neurotoxicity via glutamate release from hemichannels of activated microglia in an autocrine manner

Hideyuki Takeuchi et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Biochemistry & Molecular Biology

Glutamate metabolizing enzymes in prefrontal cortex of Alzheimer's disease patients

GS Burbaeva et al.

NEUROCHEMICAL RESEARCH (2005)