Journal
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
Volume 70, Issue 16, Pages 1130-1166Publisher
TAYLOR & FRANCIS AS
DOI: 10.1080/00914037.2020.1785455
Keywords
Biodegradable polymers; colon targeted delivery; controlled delivery; polysaccharides
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Colon targeted drug delivery systems, which deliver drugs to the colon via oral administration to protect and ensure controlled release, have gained importance in pharmacotherapy. Various drug delivery systems have been designed to quantitatively deliver drugs to the colon and trigger the release of the drug. Different types of polymers can be used in the formulation of these systems.
The colon targeted drug delivery has a number of important implications in the field of pharmacotherapy. Oral colon targeted drug delivery systems have recently gained importance for delivering a variety of therapeutic agents for both local and systemic administration. Targeting of drugs to the colon via oral administration to protect the drug from degradation or release in the stomach and small intestine. It also ensures abrupt or controlled release of the drug in the proximal colon. Various drug delivery systems have been designed that deliver the drug quantitatively to the colon and then trigger the release of the drug. This review will cover different types of polymers which can be used in the formulation of colon targeted drug delivery systems.
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